Search Results - "Hernández, Eloy D."

p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer by Duran, Angeles, Hernandez, Eloy D., Reina-Campos, Miguel, Castilla, Elias A., Subramaniam, Shankar, Raghunandan, Sindhu, Roberts, Lewis R., Kisseleva, Tatiana, Karin, Michael, Diaz-Meco, Maria T., Moscat, Jorge

“…Hepatic stellate cells (HSCs) play critical roles in liver fibrosis and hepatocellular carcinoma (HCC). Vitamin D receptor (VDR) activation in HSCs inhibits…”
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A Macrophage NBR1-MEKK3 Complex Triggers JNK-Mediated Adipose Tissue Inflammation in Obesity by Hernandez, Eloy D., Lee, Sang Jun, Kim, Ji Young, Duran, Angeles, Linares, Juan F., Yajima, Tomoko, Müller, Timo D., Tschöp, Matthias H., Smith, Steven R., Diaz-Meco, Maria T., Moscat, Jorge

“…The c-Jun NH(2)-terminal kinase (JNK) is a critical determinant of obesity-associated inflammation and glucose intolerance. The upstream mechanisms controlling…”
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Tropifexor‐Mediated Abrogation of Steatohepatitis and Fibrosis Is Associated With the Antioxidative Gene Expression Profile in Rodents by Hernandez, Eloy D., Zheng, Lianxing, Kim, Young, Fang, Bin, Liu, Bo, Valdez, Reginald A., Dietrich, William F., Rucker, Paul V., Chianelli, Donatella, Schmeits, James, Bao, Dingjiu, Zoll, Jocelyn, Dubois, Claire, Federe, Glenn C., Chen, Lihao, Joseph, Sean B., Klickstein, Lloyd B., Walker, John, Molteni, Valentina, McNamara, Peter, Meeusen, Shelly, Tully, David C., Badman, Michael K., Xu, Jie, Laffitte, Bryan

“…Farnesoid X receptor (FXR) agonism is emerging as an important potential therapeutic mechanism of action for multiple chronic liver diseases. The bile…”
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Distinct functional roles of the two terminal halves of eukaryotic phosphofructokinase by Martínez-Costa, Oscar H, Sánchez, Valentina, Lázaro, Antonio, Hernández, Eloy D, Tornheim, Keith, Aragón, Juan J

“…Eukaryotic PFK (phosphofructokinase), a key regulatory enzyme in glycolysis, has homologous N- and C-terminal domains thought to result from duplication,…”
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Nidufexor (LMB763), a Novel FXR Modulator for the Treatment of Nonalcoholic Steatohepatitis by Chianelli, Donatella, Rucker, Paul V, Roland, Jason, Tully, David C, Nelson, John, Liu, Xiaodong, Bursulaya, Badry, Hernandez, Eloy D, Wu, Jane, Prashad, Mahavir, Schlama, Thierry, Liu, Yugang, Chu, Alan, Schmeits, James, Huang, David J, Hill, Robert, Bao, Dingjiu, Zoll, Jocelyn, Kim, Young, Groessl, Todd, McNamara, Peter, Liu, Bo, Richmond, Wendy, Sancho-Martinez, Ignacio, Phimister, Andrew, Seidel, H. Martin, Badman, Michael K, Joseph, Sean B, Laffitte, Bryan, Molteni, Valentina

“…Farnesoid X receptor (FXR) agonists are emerging as important potential therapeutics for the treatment of nonalcoholic steatohepatitis (NASH) patients, as they…”
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Subunit Interactions and Composition of the Fructose 6-Phosphate Catalytic Site and the Fructose 2,6-Bisphosphate Allosteric Site of Mammalian Phosphofructokinase by Ferreras, Cristina, Hernández, Eloy D., Martínez-Costa, Oscar H., Aragón, Juan J.

“…Mammalian phosphofructokinase originated by duplication, fusion, and divergence of a primitive prokaryotic gene, with the duplicated fructose 6-phosphate…”
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Subunit Interactions and Composition of the Fructose 6-Phosphate Catalytic Site and the Fructose 2,6-Bisphosphate Allosteric Site of Mammalian PhosphofructokinaseS by Ferreras, Cristina, Hernández, Eloy D., Martínez-Costa, Oscar H., Aragón, Juan J.

“…Mammalian phosphofructokinase originated by duplication, fusion, and divergence of a primitive prokaryotic gene, with the duplicated fructose 6-phosphate…”
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Organization and Structural Features of Phosphofructokinase and other Glycolytic Enzymes to Meet their Role in Energy Metabolism by Aragón, Juan J., Ferreras, Cristina, Sánchez, Cristina, Sánchez, Valentina, Hernández, Eloy D., Hermida, Carmen, Adan, Cristina, Garesse, Rafael, Martínez-Costa, Oscar H.

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