Search Results - "Hermes, J. D"

Anthrax Lethal Factor Inhibition by Shoop, W. L., Xiong, Y., Wiltsie, J., Woods, A., Guo, J., Pivnichny, J. V., Felcetto, T., Michael, B. F., Bansal, A., Cummings, R. T., Cunningham, B. R., Friedlander, A. M., Douglas, C. M., Patel, S. B., Wisniewski, D., Scapin, G., Salowe, S. P., Zaller, D. M., Chapman, K. T., Scolnick, E. M., Schmatz, D. M., Bartizal, K., MacCoss, M., Hermes, J. D., Campbell, William C.

“…The primary virulence factor of Bacillus anthracis is a secreted zinc-dependent metalloprotease toxin known as lethal factor (LF) that is lethal to the host…”
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Measurement of pitch by subharmonic summation by HERMES, D. J

“…In order to account for the phenomenon of virtual pitch, various theories assume implicitly or explicitly that each spectral component introduces a series of…”
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Searching Sequence Space by Definably Random Mutagenesis: Improving the Catalytic Potency of an Enzyme by Hermes, Jeffrey D., Blacklow, Stephen C., Knowles, Jeremy R.

“…How easy is it to improve the catalytic power of an enzyme? To address this question, the gene encoding a sluggish mutant triose-phosphate isomerase…”
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The frequency scale of speech intonation by HERMES, D. J, VAN GESTEL, J. C

“…In intonation research, prominence-lending pitch movements have either been described on a linear or on a logarithmic frequency scale. An experiment has been…”
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Vowel-onset detection by HERMES, D. J

“…An algorithm is presented that correctly detects the large majority of vowel onsets in fluent speech. The algorithm is based on the simple assumption that…”
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FK-506-binding protein: three-dimensional structure of the complex with the antagonist L-685,818 by Becker, J.W., Rotonda, J., McKeever, B.M., Chan, H.K., Marcy, A.I., Wiederrecht, G., Hermes, J.D., Springer, J.P.

“…L-685,818 differs only slightly in structure from the immunosuppressive drug FK-506, and both compounds bind with comparable affinity to the 12-kDa…”
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Presentation of endogenous peptides to MHC class I-restricted cytotoxic T lymphocytes in transport deletion mutant T2 cells by Zweerink, HJ, Gammon, MC, Utz, U, Sauma, SY, Harrer, T, Hawkins, JC, Johnson, RP, Sirotina, A, Hermes, JD, Walker, BD

“…The ability of minigene-encoded viral peptide epitopes to be presented by class I molecules in the absence of MHC-encoded transporters has been evaluated in…”
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Nuclear Receptors Have Distinct Affinities for Coactivators: Characterization by Fluorescence Resonance Energy Transfer by Zhou, Gaochao, Cummings, Richard, Li, Ying, Mitra, Sudha, Wilkinson, Hilary A, Elbrecht, Alex, Hermes, Jeffrey D, Schaeffer, James M, Smith, Roy G, Moller, David E

“…Ligand-dependent interactions between nuclear receptors and members of a family of nuclear receptor coactivators are associated with transcriptional…”
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A reliable method for random mutagenesis: the generation of mutant libraries using spiked oligodeoxyribonucleotide primers by Hermes, J D, Parekh, S M, Blacklow, S C, Köster, H, Knowles, J R

“…A new procedure for the production of a defined library of random mutants is described. Long spiked oligodeoxyribonucleotides (oligos), in which a…”
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Stromelysin‐1: Three‐dimensional structure of the inhibited catalytic domain and of the C‐truncated proenzyme by Becker, Joseph W., Marcy, Alice I., Rokosz, Laura L., Axel, Melinda G., Burbaum, Jonathan J., Fitzgerald, Paula M.D., Cameron, Patricia M., Esser, Craig K., Hagmann, William K., Hermes, Jeffrey D., Springer, James P.

“…The proteolytic enzyme stromelysin‐1 is a member of the family of matrix metalloproteinases and is believed to play a role in pathological conditions such as…”
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Human fibroblast stromelysin catalytic domain: expression, purification, and characterization of a C-terminally truncated form by Marcy, Alice I, Eiberger, Laura L, Harrison, Richard, Chan, H. Karen, Hutchinson, Nancy I, Hagmann, William K, Cameron, Patricia M, Boulton, David A, Hermes, Jeffrey D

“…Stromelysin-1 is a member of a tissue metalloproteinase family whose members are all capable of degrading extracellular matrix components. A truncated form of…”
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Characterization of zinc-binding sites in human stromelysin-1: stoichiometry of the catalytic domain and identification of a cysteine ligand in the proenzyme by Salowe, Scott P, Marcy, Alice I, Cuca, Gregory C, Smith, Catherine K, Kopka, Ihor E, Hagmann, William K, Hermes, Jeffrey D

“…A determination of the zinc stoichiometry of the catalytic domain of the human matrix metalloproteinase stromelysin-1 has been carried out using enzyme…”
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Evidence from nitrogen-15 and solvent deuterium isotope effects on the chemical mechanism of adenosine deaminase by Weiss, Paul M, Cook, P. F, Hermes, J. D, Cleland, W. W

“…We have determined 15N isotope effects and solvent deuterium isotope effects for adenosine deaminase using both adenosine and the slow alternate substrate…”
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A Peptide-Based Fluorescence Resonance Energy Transfer Assay for Bacillus anthracis Lethal Factor Protease by Cummings, Richard T., Salowe, Scott P., Cunningham, Barry R., Wiltsie, Judyann, Park, Young Whan, Sonatore, Lisa M., Wisniewski, Douglas, Douglas, Cameron M., Hermes, Jeffrey D., Scolnick, Edward M.

“…A fluorescence resonance energy transfer assay has been developed for monitoring Bacillus anthracis lethal factor (LF) protease activity. A fluorogenic 16-mer…”
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Tetrapeptide derived inhibitors of complexation of a class II MHC: fully unnatural ligands by Brian Jones, A., Acton, John J., Adams, Alan D., Yuen, Winston, Nichols, Elizabeth A., Schwartz, Cheryl D., Wicker, Linda S., Hermes, Jeffrey D.

“…Tetrapeptide derived major histocompatability (MHC) II ligands have been developed that contain no unadulterated peptide bonds. These are the ‘least peptidic’…”
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Tetrapeptide derived inhibitors of complexation of a class II MHC: the peptide backbone is not inviolate by Jones, A.Brian, Acton, John J., Rivetna, Meheryar N., Cummings, Richard T., Cubbon, Rose M., Nichols, Elizabeth A., Schwartz, Cheryl D., Wicker, Linda S., Hermes, Jeffrey D.

“…Major histocompatabilty (MHC) proteins rely heavily on peptide backbone recognition for ligation. Nonetheless, modifications to the polyamide backbone of a…”
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Teaching intonation to young deaf children with the intonation meter by Spaai, G W, Derksen, E S, Hermes, D J, Kaufholz, P A

“…Incorrect production of intonation contours is a common phonatory problem in prelingually, profoundly deaf speakers. To help deaf speakers improve this, a…”
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Kinetic Mechanism for p38 MAP Kinase by LoGrasso, Philip V, Frantz, Betsy, Rolando, Anna M, O'Keefe, Stephen J, Hermes, Jeffery D, O'Neill, Edward A

“…p38 has been shown to be a critical enzyme in the pro-inflammatory cytokine pathway and is a member of the mitogen-activated protein (MAP) kinase family. While…”
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Chloroform-soluble nucleotides in Escherichia coli. Role of CDP-diglyceride in the enzymatic cytidylylation of phosphomonoester acceptors by Bulawa, C E, Hermes, J D, Raetz, C R

“…CDP-diglyceride, the precursor of all the phospholipids in Escherichia coli, is cleaved in vitro to phosphatidic acid and CMP by a membrane-bound hydrolase…”
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Measuring the Perceptual Similarity of Pitch Contours by Hermes, Dik J

“…This study investigated the effectiveness of four different methods for measuring the similarity of pitch contours. The correlation coefficient between two…”
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