Search Results - "Herman, Terence"

Significance of hematopoietic surface antigen CD34 in neuroblastoma prognosis and the genetic landscape of CD34-expressing neuroblastoma CSCs by Aravindan, Natarajan, Somasundaram, Dinesh Babu, Herman, Terence S., Aravindan, Sheeja

“…High-risk neuroblastoma (HR-NB) is branded with hematogenous metastasis, relapses, and dismal long-term survival. Intensification of consolidation therapy with…”
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Anti-pancreatic cancer deliverables from sea: first-hand evidence on the efficacy, molecular targets and mode of action for multifarious polyphenols from five different brown-algae by Aravindan, Sheeja, Delma, Caroline R, Thirugnanasambandan, Somasundaram S, Herman, Terence S, Aravindan, Natarajan

“…Pancreatic cancer (PC) remains the fourth leading cause of cancer death with an unacceptable survival that has remained relatively unchanged over the past 25…”
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Novel synthetic monoketone transmute radiation-triggered NFκB-dependent TNFα cross-signaling feedback maintained NFκB and favors neuroblastoma regression by Aravindan, Sheeja, Natarajan, Mohan, Awasthi, Vibhudutta, Herman, Terence S, Aravindan, Natarajan

“…Recently, we demonstrated that radiation (IR) instigates the occurrence of a NFκB-TNFα feedback cycle which sustains persistent NFκB activation in…”
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Acquired genetic alterations in tumor cells dictate the development of high-risk neuroblastoma and clinical outcomes by Khan, Faizan H, Pandian, Vijayabaskar, Ramraj, Satishkumar, Natarajan, Mohan, Aravindan, Sheeja, Herman, Terence S, Aravindan, Natarajan

“…Determining the driving factors and molecular flow-through that define the switch from favorable to aggressive high-risk disease is critical to the betterment…”
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Targeting acquired oncogenic burden in resilient pancreatic cancer: a novel benefit from marine polyphenols by Aravindan, Sheeja, Somasundaram, Dinesh Babu, Somasundaram, Somasundaram T., Natarajan, Mohan, Herman, Terence S., Aravindan, Natarajan

“…The upsurge of marine-derived therapeutics for cancer treatment is evident, with many drugs in clinical use and in clinical trials. Seaweeds harbor large…”
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Impact of curcumin, raspberry extract, and neem leaf extract on rel protein-regulated cell death/radiosensitization in pancreatic cancer cells by Veeraraghavan, Jamunarani, Natarajan, Mohan, Lagisetty, Pallavi, Awasthi, Vibhudutta, Herman, Terence S, Aravindan, Natarajan

“…Nuclear factor κB (NF-κB) plays an intrinsic role in promoting growth, angiogenesis, and metastasis in pancreatic cancer (PC) and serves as a mechanism…”
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Cancer stem cells in neuroblastoma therapy resistance by Aravindan, Natarajan, Jain, Drishti, Somasundaram, Dinesh Babu, Herman, Terence S, Aravindan, Sheeja

“…Neuroblastoma (NB) is the most common cancer of infancy and accounts for nearly one tenth of pediatric cancer deaths. This mortality rate has been attributed…”
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Reorganization of metastamiRs in the evolution of metastatic aggressive neuroblastoma cells by Khan, Faizan H, Pandian, Vijayabaskar, Ramraj, Satishkumar, Aravindan, Sheeja, Herman, Terence S, Aravindan, Natarajan

“…MetastamiRs have momentous clinical relevance and have been correlated with disease progression in many tumors. In this study, we identified neuroblastoma…”
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Serum-circulating miRNAs predict neuroblastoma progression in mouse model of high-risk metastatic disease by Ramraj, Satish Kumar, Aravindan, Sheeja, Somasundaram, Dinesh Babu, Herman, Terence S, Natarajan, Mohan, Aravindan, Natarajan

“…Circulating miRNAs have momentous clinical relevance as prognostic biomarkers and in the progression of solid tumors. Recognizing novel candidates of…”
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Droplet digital PCR as an alternative to FISH for MYCN amplification detection in human neuroblastoma FFPE samples by Somasundaram, Dinesh Babu, Aravindan, Sheeja, Yu, Zhongxin, Jayaraman, Muralidharan, Tran, Ngoc T B, Li, Shibo, Herman, Terence S, Aravindan, Natarajan

“…MYCN amplification directly correlates with the clinical course of neuroblastoma and poor patient survival, and serves as the most critical negative prognostic…”
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MicroRNAs in neuroblastoma tumorigenesis, therapy resistance, and disease evolution by Aravindan, Natarajan, Subramanian, Karthikeyan, Somasundaram, Dinesh Babu, Herman, Terence S, Aravindan, Sheeja

“…Neuroblastoma (NB) deriving from neural crest cells is the most common extra-cranial solid cancer at infancy. NB originates within the peripheral sympathetic…”
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Abstract 2401: RD3-loss orchestrates GC-signaling independent evolution of progressive neuroblastoma by Meghna, Singh, Rachel, Wolansky, Herman, Terence S., Aravindan, Natarajan

“…Abstract Recently we recognized the transcriptional/translational loss of Retinal degeneration Protein 3 (RD3) in high-risk progressive neuroblastoma (HR-NB)…”
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Curcumin Regulates Low-Linear Energy Transfer γ-Radiation-Induced NFκB-Dependent Telomerase Activity in Human Neuroblastoma Cells by Aravindan, Natarajan, Ph.D, Veeraraghavan, Jamunarani, M.V.Sc, Madhusoodhanan, Rakhesh, Ph.D, Herman, Terence S., M.D, Natarajan, Mohan, Ph.D

“…Purpose We recently reported that curcumin attenuates ionizing radiation (IR)-induced survival signaling and proliferation in human neuroblastoma cells. Also,…”
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De novo regulation of RD3 synthesis in residual neuroblastoma cells after intensive multi-modal clinical therapy harmonizes disease evolution by Somasundaram, Dinesh Babu, Subramanian, Karthikeyan, Aravindan, Sheeja, Yu, Zhongxin, Natarajan, Mohan, Herman, Terence, Aravindan, Natarajan

“…Most high-risk neuroblastomas that initially respond to therapy will ultimately relapse. Currently, no curative treatment is available. Acquired…”
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Molecular basis of 'hypoxic' breast cancer cell radio-sensitization: phytochemicals converge on radiation induced Rel signaling by Aravindan, Sheeja, Natarajan, Mohan, Herman, Terence S, Awasthi, Vibhudutta, Aravindan, Natarajan

“…Heterogeneously distributed hypoxic areas are a characteristic property of locally advanced breast cancers (BCa) and generally associated with therapeutic…”
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Ocular malignancies treated with iodine-125 low dose rate (LDR) brachytherapy at a single high-volume institution: A retrospective review by Richards, Zachary, Nguyen, My-Lien, Kutteh, Michael, Ahmad, Salahuddin, Henson, Christina, Firestone, Brian, Herman, Terence S., Herman, Tania De La Fuente

“…The aim of our study is to document our cases of choroidal melanoma treated with low dose rate (LDR) brachytherapy and to correlate the dosimetry and…”
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Silencing BMI1 radiosensitizes human breast cancer cells by inducing DNA damage and autophagy by Griffith, James, Andrade, Daniel, Mehta, Meghna, Berry, William, Benbrook, Doris M, Aravindan, Natarajan, Herman, Terence S, Ramesh, Rajagopal, Munshi, Anupama

“…Overexpression of BMI1 in human cancer cells, a member of the polycomb group of repressive complexes, correlates with advanced stage of disease, aggressive…”
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Dosimetric considerations when utilizing Venezia, Capri, Rotte double tandem, and tandem and ring with interstitial needles for the treatment of gynecological cancers with high dose rate brachytherapy by Schnell, Erich, Thompson, Spencer, Ahmad, Salahuddin, Herman, Terence S., De La Fuente Herman, Tania

“…This work evaluated the difference in dosimetry of high dose rate (HDR) brachytherapy treatments between plans using advanced multichannel applicators and…”
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The Efficacy of Radiation Therapy in the Treatment of Graves’ Orbitopathy by Matthiesen, Chance, M.D, Thompson, J. Spencer, M.D, Thompson, David, Ph.D, Farris, Bradley, M.D, Wilkes, Byron, M.D, Ahmad, Salahuddin, Ph.D, Herman, Terence, M.D, Bogardus, Carl, M.D

“…Purpose To review our institutional outcomes of patients treated with radiation therapy (RT) for Graves’ orbitopathy (GO), assess the role of orbital…”
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Melatonin as a radioprotective agent: a review by Vijayalaxmi, Reiter, Russel J, Tan, Dun-Xian, Herman, Terence S, Thomas, Jr, Charles R

“…Melatonin (N-acetyl-5-methoxytryptamine), the chief secretory product of the pineal gland in the brain, is well known for its functional versatility. In…”
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