Search Results - "Herman, Nancy S"

Allergen uptake, activation, and IL-23 production by pulmonary myeloid DCs drives airway hyperresponsiveness in asthma-susceptible mice by Lewkowich, Ian P, Lajoie, Stephane, Clark, Jennifer R, Herman, Nancy S, Sproles, Alyssa A, Wills-Karp, Marsha

“…Maladaptive, Th2-polarized inflammatory responses are integral to the pathogenesis of allergic asthma. As regulators of T cell activation, dendritic cells…”
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CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function by Lewkowich, Ian P, Herman, Nancy S, Schleifer, Kathleen W, Dance, Matthew P, Chen, Brian L, Dienger, Krista M, Sproles, Alyssa A, Shah, Jaimin S, Köhl, Jörg, Belkaid, Yasmine, Wills-Karp, Marsha

“…The role of natural CD4+CD25+ regulatory T (T reg) cells in the control of allergic asthma remains poorly understood. We explore the impact of T reg cell…”
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A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma by Köhl, Jörg, Baelder, Ralf, Lewkowich, Ian P, Pandey, Manoj K, Hawlisch, Heiko, Wang, Lihua, Best, Jennifer, Herman, Nancy S, Sproles, Alyssa A, Zwirner, Jörg, Whitsett, Jeffrey A, Gerard, Craig, Sfyroera, Georgia, Lambris, John D, Wills-Karp, Marsha

“…Complement component 5 (C5) has been described as either promoting or protecting against airway hyperresponsiveness (AHR) in experimental allergic asthma,…”
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IL-21 receptor signalling partially mediates Th2-mediated allergic airway responses by Lajoie, S., Lewkowich, I., Herman, N. S., Sproles, A., Pesce, J. T., Wynn, T. A., Grusby, M. J., Hamid, Q., Wills-Karp, M.

“…Summary Background Interleukin‐21 (IL‐21) has been implicated in the development of Th2‐mediated immune responses; however, the exact role it plays in allergic…”
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CD4 super(+)CD25 super(+) T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function by Lewkowich, Ian P, Herman, Nancy S, Schleifer, Kathleen W, Dance, Matthew P, Chen, Brian L, Dienger, Krista M, Sproles, Alyssa A, Shah, Jaimin S, Koehl, Joerg, Belkaid, Yasmine, Wills-Karp, Marsha

“…The role of natural CD4 super(+)CD25 super(+) regulatory T (T reg) cells in the control of allergic asthma remains poorly understood. We explore the impact of…”
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Unique and overlapping gene expression patterns driven by IL-4 and IL-13 in the mouse lung by Lewis, Christina C., PhD, Aronow, Bruce, PhD, Hutton, John, MD, Santeliz, Joanna, PhD, Dienger, Krista, BS, Herman, Nancy, BS, Finkelman, Fred D., MD, Wills-Karp, Marsha, PhD

“…Background Allergic asthma results from inappropriate TH 2-mediated inflammation. Both IL-4 and IL-13 contribute to asthma pathogenesis, but IL-4 predominantly…”
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