Search Results - "Herman, Dorota"

Low concentration cell painting images enable the identification of highly potent compounds by Ha, Son V., Jaensch, Steffen, Freitas, Lorena G. A., Herman, Dorota, Czodrowski, Paul, Ceulemans, Hugo

“…Image-based models that use features extracted from cell microscopy images can estimate the activity of small molecules in various biological assays…”
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Leaf Growth Response to Mild Drought: Natural Variation in Arabidopsis Sheds Light on Trait Architecture by Clauw, Pieter, Coppens, Frederik, Korte, Arthur, Herman, Dorota, Slabbinck, Bram, Dhondt, Stijn, Van Daele, Twiggy, De Milde, Liesbeth, Vermeersch, Mattias, Maleux, Katrien, Maere, Steven, Gonzalez, Nathalie, Inzé, Dirk

“…Plant growth and crop yield are negatively affected by a reduction in water availability. However, a clear understanding of how growth is regulated under…”
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Using single‐plant‐omics in the field to link maize genes to functions and phenotypes by Cruz, Daniel Felipe, De Meyer, Sam, Ampe, Joke, Sprenger, Heike, Herman, Dorota, Van Hautegem, Tom, De Block, Jolien, Inzé, Dirk, Nelissen, Hilde, Maere, Steven

“…Most of our current knowledge on plant molecular biology is based on experiments in controlled laboratory environments. However, translating this knowledge…”
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Combined Large-Scale Phenotyping and Transcriptomics in Maize Reveals a Robust Growth Regulatory Network by Baute, Joke, Herman, Dorota, Coppens, Frederik, De Block, Jolien, Slabbinck, Bram, Dell'Acqua, Matteo, Pè, Mario Enrico, Maere, Steven, Nelissen, Hilde, Inzé, Dirk

“…Leaves are vital organs for biomass and seed production because of their role in the generation of metabolic energy and organic compounds. A better…”
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Natural Variation of Molecular and Morphological Gibberellin Responses by Nam, Youn-Jeong, Herman, Dorota, Blomme, Jonas, Chae, Eunyoung, Kojima, Mikiko, Coppens, Frederik, Storme, Veronique, Van Daele, Twiggy, Dhondt, Stijn, Sakakibara, Hitoshi, Weigel, Detlef, Inzé, Dirk, Gonzalez, Nathalie

“…Although phytohormones such as gibberellins are essential for many conserved aspects of plant physiology and development, plants vary greatly in their…”
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Selection of organisms for the co-evolution-based study of protein interactions by Herman, Dorota, Ochoa, David, Juan, David, Lopez, Daniel, Valencia, Alfonso, Pazos, Florencio

“…The prediction and study of protein interactions and functional relationships based on similarity of phylogenetic trees, exemplified by the mirrortree and…”
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Adaptation for protein synthesis efficiency in a naturally occurring self-regulating operon by Herman, Dorota, Thomas, Christopher M, Stekel, Dov J

“…The korAB operon in RK2 plasmids is a beautiful natural example of a negatively and cooperatively self-regulating operon. It has been particularly well…”
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Global transcription regulation of RK2 plasmids: a case study in the combined use of dynamical mathematical models and statistical inference for integration of experimental data and hypothesis exploration by Herman, Dorota, Thomas, Christopher M, Stekel, Dov J

“…IncP-1 plasmids are broad host range plasmids that have been found in clinical and environmental bacteria. They often carry genes for antibiotic resistance or…”
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Chemistry-Based Modeling on Phenotype-Based Drug-Induced Liver Injury Annotation: From Public to Proprietary Data by Moein, Mohammad, Heinonen, Markus, Mesens, Natalie, Chamanza, Ronnie, Amuzie, Chidozie, Will, Yvonne, Ceulemans, Hugo, Kaski, Samuel, Herman, Dorota

“…Drug-induced liver injury (DILI) is an important safety concern and a major reason to remove a drug from the market. Advancements in recent machine learning…”
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The reduction in maize leaf growth under mild drought affects the transition between cell division and cell expansion and cannot be restored by elevated gibberellic acid levels by Nelissen, Hilde, Sun, Xiao‐Huan, Rymen, Bart, Jikumaru, Yusuke, Kojima, Mikko, Takebayashi, Yumiko, Abbeloos, Rafael, Demuynck, Kirin, Storme, Veronique, Vuylsteke, Marnik, De Block, Jolien, Herman, Dorota, Coppens, Frederik, Maere, Steven, Kamiya, Yuji, Sakakibara, Hitoshi, Beemster, Gerrit T.S., Inzé, Dirk

“…Summary Growth is characterized by the interplay between cell division and cell expansion, two processes that occur separated along the growth zone at the…”
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Leveraging Cell Painting Images to Expand the Applicability Domain and Actively Improve Deep Learning Quantitative Structure–Activity Relationship Models by Herman, Dorota, Kańduła, Maciej M., Freitas, Lorena G. A., van Dongen, Caressa, Le Van, Thanh, Mesens, Natalie, Jaensch, Steffen, Gustin, Emmanuel, Micholt, Liesbeth, Lardeau, Charles-Hugues, Varsakelis, Christos, Reumers, Joke, Zoffmann, Sannah, Will, Yvonne, Peeters, Pieter J., Ceulemans, Hugo

“…The search for chemical hit material is a lengthy and increasingly expensive drug discovery process. To improve it, ligand-based quantitative…”
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Correlation analysis of the transcriptome of growing leaves with mature leaf parameters in a maize RIL population by Baute, Joke, Herman, Dorota, Coppens, Frederik, De Block, Jolien, Slabbinck, Bram, Dell'Acqua, Matteo, Pè, Mario Enrico, Maere, Steven, Nelissen, Hilde, Inzé, Dirk

“…To sustain the global requirements for food and renewable resources, unraveling the molecular networks underlying plant growth is becoming pivotal. Although…”
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Natural Variation of Molecular and Morphological Gibberellin Responses1[OPEN] by Nam, Youn-Jeong, Herman, Dorota, Blomme, Jonas, Chae, Eunyoung, Kojima, Mikiko, Coppens, Frederik, Storme, Veronique, Van Daele, Twiggy, Dhondt, Stijn, Sakakibara, Hitoshi, Weigel, Detlef, Inzé, Dirk, Gonzalez, Nathalie

“…Genetic perturbation of endogenous gibberellin levels shows unexpected flexibility in the wiring of regulatory networks underlying hormone metabolism and…”
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Combined Large-Scale Phenotyping and Transcriptomics in Maize Reveals a Robust Growth Regulatory Network1[OPEN] by Baute, Joke, Herman, Dorota, Coppens, Frederik, De Block, Jolien, Slabbinck, Bram, Dell’Acqua, Matteo, Pè, Mario Enrico, Maere, Steven, Nelissen, Hilde, Inzé, Dirk

“…Combining in-depth phenotyping with transcript profiling in maize recombinant inbred lines untangles the genetic control of complex traits. Leaves are vital…”
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Deterministic and stochastic modelling of transcriptional regulation of plasmid rk2 by Herman, Dorota

“…Plasmids RK2 are broad host range plasmids and they carry genes for antibioticresistance. Their central control operon, encoding two global regulators KorA and…”
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