Search Results - "Herlin, Maria"

Exploring telomere length in mother-newborn pairs in relation to exposure to multiple toxic metals and potential modifying effects by nutritional factors by Herlin, Maria, Broberg, Karin, Igra, Annachiara Malin, Li, Huiqi, Harari, Florencia, Vahter, Marie

“…The uterine environment may influence telomere length at birth, which is essential for cellular function, aging, and disease susceptibility over the lifespan…”
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Differential expression of the inflammatory ciita gene may be accompanied by altered bone properties in intact sex steroid-deficient female rats by Jensen, Vivi Fh, Swanberg, Maria, Herlin, Maria, McGuigan, Fiona E, Jørgensen, Niklas R, Akesson, Kristina E

“…The class II transactivator (CIITA), encoded by the CIITA gene, controls expression of immune response regulators, which affect bone homeostasis. Previously,…”
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Skeletal and dental effects on rats following in utero/lactational exposure to the non-dioxin-like polychlorinated biphenyl PCB 180 by Romero, Ashly N, Herlin, Maria, Finnilä, Mikko, Korkalainen, Merja, Håkansson, Helen, Viluksela, Matti, Sholts, Sabrina B

“…Polychlorinated biphenyls (PCBs) are a large class of persistent organic pollutants that are potentially harmful to human and wildlife health. Although a small…”
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A 28-Day Oral Dose Toxicity Study Enhanced to Detect Endocrine Effects of Hexabromocyclododecane in Wistar Rats by van der Ven, Leo T. M., Verhoef, Aart, van de Kuil, Ton, Slob, Wout, Leonards, Pim E. G., Visser, Theo J., Hamers, Timo, Herlin, Maria, Håkansson, Helen, Olausson, Hanna, Piersma, Aldert H., Vos, Josephus G.

“…A 28-day repeated dose study in rats (OECD407) enhanced for endocrine and immune parameters was performed with hexabromocyclododecane (HBCD). Rats were exposed…”
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Craniofacial form is altered by chronic adult exposure to 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD) in Han/Wistar and Long-Evans rats with different aryl hydrocarbon receptor (AhR) structures by Sholts, Sabrina B, Esteban, Javier, Herlin, Maria, Viluksela, Matti, Håkansson, Helen

“…Mammalian bone has shown a variety of responses to 2,3,7,8-tetrachlorodibenzo- -dioxin (TCDD) exposure in experimental and wildlife studies. Although many…”
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Polymorphisms in inflammation associated genes ALOX15 and IL-6 are associated with bone properties in young women and fracture in elderly by Herlin, Maria, McGuigan, Fiona E, Luthman, Holger, Åkesson, Kristina

“…Abstract Purpose ALOX12 and ALOX15 encode arachidonate lipoxygenases which produce lipid metabolites involved in inflammatory processes. Metabolites generated…”
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Bone toxicity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and the retinoid system: A causality analysis anchored in osteoblast gene expression and mouse data by Herlin, Maria, Sánchez-Pérez, Ismael, Esteban, Javier, Korkalainen, Merja, Barber, Xavier, Finnilä, Mikko A.J., Hamscher, Gerd, Joseph, Bertrand, Viluksela, Matti, Håkansson, Helen

“…•TCDD-induced effects on mouse bone are associated with increased circulating REOH.•TCDD represses Crabp2 expression indicating reduced nuclear translocation…”
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Bone properties in a rat model of differential expression of the inflammatory Ciita gene by Jensen, Vivi, McGuigan, Fiona E., Swanberg, Maria, Herlin, Maria, Jørgensen, Niklas, Akesson, Kristina

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Analysis of RAMP3 gene polymorphism with body composition and bone density in young and elderly women by Prakash, Jai, Herlin, Maria, Kumar, Jitender, Garg, Gaurav, Akesson, Kristina E., Grabowski, Peter S., Skerry, Tim M., Richards, Gareth O., McGuigan, Fiona E.A.

“…The Receptor Activity Modifying Proteins (RAMPs) are a group of accessory proteins, of which there are three in humans, that interact with a number of…”
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Endocrine, metabolic and apical effects of in utero and lactational exposure to non-dioxin-like 2,2′,3,4,4′,5,5′-heptachlorobiphenyl (PCB 180): A postnatal follow-up study in rats by Alarcón, Sonia, Esteban, Javier, Roos, Robert, Heikkinen, Päivi, Sánchez-Pérez, Ismael, Adamsson, Annika, Toppari, Jorma, Koskela, Antti, Finnilä, Mikko A.J., Tuukkanen, Juha, Herlin, Maria, Hamscher, Gerd, Leslie, Heather A., Korkalainen, Merja, Halldin, Krister, Schrenk, Dieter, Håkansson, Helen, Viluksela, Matti

“…•PCB 180 reduced progressively serum testosterone and fT3 levels in offspring.•PCB 180 IUL exposure altered the retinoid system in offspring.•Enzyme induction…”
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New insights to the role of aryl hydrocarbon receptor in bone phenotype and in dioxin-induced modulation of bone microarchitecture and material properties by Herlin, Maria, Finnilä, Mikko A.J., Zioupos, Peter, Aula, Antti, Risteli, Juha, Miettinen, Hanna M., Jämsä, Timo, Tuukkanen, Juha, Korkalainen, Merja, Håkansson, Helen, Viluksela, Matti

“…Bone is a target for high affinity aryl hydrocarbon receptor (AHR) ligands, such as dioxins. Although bone morphology, mineral density and strength are…”
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Exposure to endocrine disruptors is associated with alterations of the retinoid system in both experimental animal and human studies by Esteban, Javier, Galbán-Velázquez, Suylen, Sánchez-Pérez, Ismael, Serrano-Maciá, Marina, Pehlivanli, Ayça Çakmak, Barber, Xavier, Rylander, Lars, Trnovec, Tomáš, Wimmerová, Soňa, Murínová, L'ubica Palkovičová, Čonka, Kamil, Jurečková, Dana, Hamscher, Gerd, Herlin, Maria, Arrebola, Juan P, Çakmak, Gonca, Pellín, Ma de la Cruz, Barril, José, Pohjanvirta, Raimo, Viluksela, Matti, Håkansson, Helen

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Toxicological profile of ultrapure 2,2',3,4,4',5,5'-heptachlorbiphenyl (PCB 180) in adult rats by Viluksela, Matti, Heikkinen, Päivi, van der Ven, Leo T M, Rendel, Filip, Roos, Robert, Esteban, Javier, Korkalainen, Merja, Lensu, Sanna, Miettinen, Hanna M, Savolainen, Kari, Sankari, Satu, Lilienthal, Hellmuth, Adamsson, Annika, Toppari, Jorma, Herlin, Maria, Finnilä, Mikko, Tuukkanen, Juha, Leslie, Heather A, Hamers, Timo, Hamscher, Gerd, Al-Anati, Lauy, Stenius, Ulla, Dervola, Kine-Susann, Bogen, Inger-Lise, Fonnum, Frode, Andersson, Patrik L, Schrenk, Dieter, Halldin, Krister, Håkansson, Helen

“…PCB 180 is a persistent non-dioxin-like polychlorinated biphenyl (NDL-PCB) abundantly present in food and the environment. Risk characterization of NDL-PCBs is…”
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Endocrine effects of hexabromocyclododecane (HBCD) in a one-generation reproduction study in Wistar rats by van der Ven, Leo T.M., van de Kuil, Ton, Leonards, Pim E.G., Slob, Wout, Lilienthal, Hellmuth, Litens, Sabina, Herlin, Maria, Håkansson, Helen, Cantón, Rocío F., van den Berg, Martin, Visser, Theo J., van Loveren, Henk, Vos, Josephus G., Piersma, Aldert H.

“…The brominated flame retardant (BFR) hexabromocyclododecane was tested in a one-generation reproduction assay in Wistar rats, enhanced for endocrine…”
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Inhibitory effects on osteoblast differentiation in vitro by the polychlorinated biphenyl mixture Aroclor 1254 are mainly associated with the dioxin-like constituents by Herlin, Maria, Öberg, Mattias, Ringblom, Joakim, Joseph, Bertrand, Korkalainen, Merja, Viluksela, Matti, Heimeier, Rachel A., Håkansson, Helen

“…•We compared effects of Aroclor 1254 and TCDD on osteoblast differentiation markers.•Relative potency (REP) values were derived from concentration-effect…”
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Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on bone material properties by Finnilä, Mikko A.J, Zioupos, Peter, Herlin, Maria, Miettinen, Hanna M, Simanainen, Ulla, Håkansson, Helen, Tuukkanen, Juha, Viluksela, Matti, Jämsä, Timo

“…Abstract Dioxins are known to decrease bone strength, architecture and density. However, their detailed effects on bone material properties are unknown. Here…”
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Gestational and lactational exposure to the polychlorinated biphenyl mixture Aroclor 1254 modulates retinoid homeostasis in rat offspring by Esteban, Javier, Elabbas, Lubna E., Borg, Daniel, Herlin, Maria, Åkesson, Agneta, Barber, Xavier, Hamscher, Gerd, Nau, Heinz, Bowers, Wayne J., Nakai, Jamie S., Viluksela, Matti, Håkansson, Helen

“…•Gestational and lactational exposure to A1254 altered retinoid levels in liver, kidney and serum in rat dams and offspring.•Hepatic retinoids were associated…”
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Characterization of Dioxin-Induced Bone Tissue Modulations : Investigating the Role of AhR and the Retinoid System by Herlin, Maria

“…All individuals are exposed to a large number of chemicals from multiple sources, and concern is growing that many everyday chemicals, alone or in combination,…”
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In Utero and Lactational Exposure to a Mixture of Environmental Contaminants Detected in Canadian Arctic Human Populations Alters Retinoid Levels in Rat Offspring with Low Margins of Exposure by Elabbas, Lubna E., Esteban, Javier, Barber, Xavier, Hamscher, Gerd, Nau, Heinz, Bowers, Wayne J., Nakai, Jamie S., Herlin, Maria, Åkesson, Agneta, Viluksela, Matti, Borg, Daniel, Håkansson, Helen

“…Arctic inhabitants are highly exposed to persistent organic pollutants (POP), which may produce adverse health effects. This study characterized alterations in…”
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Quantitative characterization of changes in bone geometry, mineral density and biomechanical properties in two rat strains with different Ah-receptor structures after long-term exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin by Herlin, Maria, Kalantari, Fereshteh, Stern, Natalia, Sand, Salomon, Larsson, Sune, Viluksela, Matti, Tuomisto, Jouni T, Tuomisto, Jouko, Tuukkanen, Juha, Jämsä, Timo, Lind, P. Monica, Håkansson, Helen

“…Abstract Background Both industrial chemicals and environmental pollutants can interfere with bone modeling and remodeling. Recently, detailed toxicological…”
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