Search Results - "Herington, AC"

Expression and action of the growth hormone releasing peptide ghrelin and its receptor in prostate cancer cell lines by Jeffery, PL, Herington, AC, Chopin, LK

“…This study has examined the expression of two new facets of the growth hormone axis, the growth hormone secretagogue receptor (GHS-R) and its recently…”
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Ghrelin and a Novel Preproghrelin Isoform Are Highly Expressed in Prostate Cancer and Ghrelin Activates Mitogen-Activated Protein Kinase in Prostate Cancer by YEH, Anthony H, JEFFERY, Penelope L, DUNCAN, Russell P, HERINGTON, Adrian C, CHOPIN, Lisa K

“…Purpose: There is evidence that the hormone ghrelin stimulates proliferation in the PC3 prostate cancer cell line although the underlying mechanism(s) remain…”
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Immunolocalization of Ghrelin and Its Functional Receptor, the Type 1a Growth Hormone Secretagogue Receptor, in the Cyclic Human Ovary by Gaytan, F., Barreiro, M. L., Chopin, L. K., Herington, A. C., Morales, C., Pinilla, L., Casanueva, F. F., Aguilar, E., Diéguez, C., Tena-Sempere, M.

“…Ghrelin is a novel 28-amino acid peptide identified as the endogenous ligand for the GH secretagogue receptor (GHS-R). Besides its hallmark central…”
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Expression of Ghrelin and Its Functional Receptor, the Type 1a Growth Hormone Secretagogue Receptor, in Normal Human Testis and Testicular Tumors by Gaytan, F., Barreiro, M. L., Caminos, J. E., Chopin, L. K., Herington, A. C., Morales, C., Pinilla, L., Paniagua, R., Nistal, M., Casanueva, F. F., Aguilar, E., Diéguez, C., Tena-Sempere, M.

“…Ghrelin, the endogenous ligand for the GH secretagogue receptor (GHS-R), has been primarily linked to the central neuroendocrine regulation of GH secretion and…”
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Kallikrein 4 (hK4) and prostate-specific antigen (PSA) are associated with the loss of E-cadherin and an epithelial-mesenchymal transition (EMT)-like effect in prostate cancer cells by Veveris-Lowe, T L, Lawrence, M G, Collard, R L, Bui, L, Herington, A C, Nicol, D L, Clements, J A

“…Prostate-specific antigen (PSA) and the related kallikrein family of serine proteases are current or emerging biomarkers for prostate cancer detection and…”
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The potential autocrine/paracrine roles of ghrelin and its receptor in hormone-dependent cancer by Jeffery, Penny L., Herington, Adrian C., Chopin, Lisa K.

“…Ghrelin is a recently identified 28 amino acid peptide capable of stimulating pituitary growth hormone release in humans. The actions of ghrelin are mediated…”
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Expression of the Disintegrin Metalloprotease, ADAM-10, in Prostate Cancer and Its Regulation by Dihydrotestosterone, Insulin-Like Growth Factor I, and Epidermal Growth Factor in the Prostate Cancer Cell Model LNCaP by MCCULLOCH, Daniel R, AKL, Pascal, SAMARATUNGA, Hemamali, HERINGTON, Adrian C, ODORICO, Dimitri M

“…Purpose: The disintegrin metalloprotease ADAM-10 is a multidomain metalloprotease that is potentially significant in tumor progression due to its extracellular…”
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Expression of Growth Hormone Secretagogue Receptor Type 1a, the Functional Ghrelin Receptor, in Human Ovarian Surface Epithelium, Mullerian Duct Derivatives, and Ovarian Tumors by Gaytan, F., Morales, C., Barreiro, M. L., Jeffery, P., Chopin, L. K., Herington, A. C., Casanueva, F. F., Aguilar, E., Dieguez, C., Tena-Sempere, M.

“…Ghrelin, the endogenous ligand of the GH secretagogue receptor (GHS-R), is a newly identified, ubiquitously expressed molecule that has been involved in a wide…”
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Expression and function of the ghrelin axis, including a novel preproghrelin isoform, in human breast cancer tissues and cell lines by Jeffery, P L, Murray, R E, Yeh, A H, McNamara, J F, Duncan, R P, Francis, G D, Herington, A C, Chopin, L K

“…While oestrogen, progesterone and growth factors, including growth hormone (GH), are clearly implicated in the pathogenesis of breast cancer, there is now…”
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Structural and Functional Evidence for the Interaction of Insulin-Like Growth Factors (IGFs) and IGF Binding Proteins with Vitronectin by Kricker, Jennifer A, Towne, Chris L, Firth, Sue M, Herington, Adrian C, Upton, Zee

“…Previous studies demonstrated that IGF-II binds directly to vitronectin (VN), whereas IGF-I binds poorly. However, binding of VN to integrins has been…”
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Human adipose tissue endothelial cells promote preadipocyte proliferation by Hutley, L J, Herington, A C, Shurety, W, Cheung, C, Vesey, D A, Cameron, D P, Prins, J B

“…Adipogenesis is preceded by development of a microvascular network, and optimal functioning of adipose tissue as an energy store and endocrine organ is…”
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Expression of the Ghrelin Axis in the Mouse: An Exon 4-Deleted Mouse Proghrelin Variant Encodes a Novel C Terminal Peptide by Jeffery, P. L, Duncan, R. P, Yeh, A. H, Jaskolski, R. A, Hammond, D. S, Herington, A. C, Chopin, L. K

“…Ghrelin, an n-octanoylated 28-amino-acid peptide capable of inducing GH secretion and food intake in humans and rats, is the endogenous ligand for the GH…”
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A potential autocrine pathway for growth hormone releasing hormone (GHRH) and its receptor in human prostate cancer cell lines by Chopin, Lisa K., Herington, Adrian C.

“…Background Recent studies have shown that GHRH antagonists inhibit prostate tumour growth and IGF‐II production both in vivo and in vitro. The mechanism…”
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The expression of the ADAMs proteases in prostate cancer cell lines and their regulation by dihydrotestosterone by McCulloch, Daniel R, Harvey, Mark, Herington, Adrian C

“…The ADAMs are a multi-functional gene family, some of which have been shown to play a role in diverse biological processes such as fertilization, myogenesis,…”
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Modeling of enzyme-substrate complexes for the metalloproteases MMP-3, ADAM-9 and ADAM-10 by Manzetti, Sergio, McCulloch, Daniel R, Herington, Adrian C, van der Spoel, David

“…The matrix metalloproteases (MMPs) and the ADAMs (A Disintegrin And Metalloprotease domain) are proteolytic enzyme families containing a catalytic zinc ion,…”
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Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-3 Are Key Regulators of Extracellular Matrix Degradation by Mouse Embryos by WHITESIDE, Eliza J, JACKSON, Michael M, HERINGTON, Adrian C, EDWARDS, Dylan R, HARVEY, Mark B

“…Embryo implantation in humans and rodents is a highly invasive yet tightly controlled process involving extracellular matrix (ECM) degradation. Matrix…”
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The outcome in Australian children with hyperinsulinism of infancy: early extensive surgery in severe cases lowers risk of diabetes by Jack, Michelle M., Greer, Ristan M., Thomsett, Michael J., Walker, Rosslyn M., Bell, John R., Choong, Catherine, Cowley, David M., Herington, Adrian C., Cotterill, Andrew M.

“…Summary aims Hyperinsulinism of infancy (HI) is characterized by unregulated insulin secretion in the presence of hypoglycaemia, often resulting in brain…”
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Effects of rosiglitazone and linoleic acid on human preadipocyte differentiation by Hutley, L. J., Newell, F. M., Joyner, J. M., Suchting, S. J., Herington, A. C., Cameron, D. P., Prins, J. B.

“…Background Peroxisome proliferator activated receptor gamma (PPARγ) is a ligand‐activated transcription factor known to be central to both adipose tissue…”
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Identification of growth hormone receptors on human growth plate chondrocytes by Werther, G A, Haynes, K, Edmonson, S, Oakes, S, Buchanan, C J, Herington, A C, Waters, M J

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Effect of protein kinase C modulation on gonadotrophin-induced granulosa cell steroidogenesis by He, H, Herington, A C, Roupas, P

“…The effect of protein kinase C (PKC) modulation on gonadotrophin-induced ovarian granulosa cell differentiation was investigated by using an activator of PKC,…”
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