Search Results - "Hergert, Tamás"
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Click Reactions Meet Flow Chemistry: An Overview of the Applications of Click Chemistry under Continuous Flow Conditions
Published in Organic process research & development (17-05-2024)“…Click reactions are versatile tools in the hands of synthetic chemists and materials scientists around the world. Coupling click chemistry with the advantages…”
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2
Access to Fluorazones by Intramolecular Dehydrative Cyclization of Aromatic Tertiary Amides: A Synthetic and Mechanistic Study
Published in Journal of organic chemistry (16-02-2018)“…An efficient synthesis has been developed for the preparation of 9H-pyrrolo[1,2-a]indol-9-ones (fluorazones) from readily available anthranilic acid…”
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3
Copper-facilitated Suzuki-Miyaura coupling for the preparation of 1,3-dioxolane-protected 5-arylthiophene-2-carboxaldehydes
Published in Tetrahedron (19-04-2018)“…5-Formyl-2-thiopheneboronic acid is a widely used building block for the synthesis of diverse structures, however, due to a significant instability its…”
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4
Multistep batch-flow hybrid synthesis of a terbinafine precursor
Published in Journal of flow chemistry (01-03-2022)“…A three-step batch-flow hybrid process has been developed for an expeditious synthesis of the enynol key intermediate of antifungal terbinafine. This procedure…”
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5
Synthesis and Investigation of Solar‐Cell Photosensitizers Having a Fluorazone Backbone
Published in European journal of organic chemistry (10-04-2017)“…A synthetic sequence for the preparation of fully conjugated 2,7‐disubstituted fluorazone (9H‐pyrrolo[1,2‐‐a]indol‐9‐one) derivatives has been developed…”
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6
Effect of Binding Linkers on the Efficiency and Metabolite Profile of Biomimetic Reactions Catalyzed by Immobilized Metalloporphyrin
Published in Metabolites (01-12-2022)“…The investigation of liver-related metabolic stability of a drug candidate is a widely used key strategy in early-stage drug discovery. Metalloporphyrin-based…”
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7
New P2X3 receptor antagonists. Part 2: Identification and SAR of quinazolinones
Published in Bioorganic & medicinal chemistry letters (15-08-2016)“…[Display omitted] Numerous potent P2X3 antagonists have been discovered and the therapeutic potential of P2X3 antagonism already comprises proof-of-concept…”
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8
A novel and convenient method for the preparation of 5-(diphenylmethylene)-1H-pyrrol-2(5H)-ones; synthesis and mechanistic study
Published in Tetrahedron (01-09-2016)“…An efficient, regioselective synthesis has been developed for the preparation of 5-(diphenylmethylene)-1H-pyrrol-2(5H)-ones from readily available 1H-pyrroles…”
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9
A novel and convenient method for the preparation of 5-(diphenylmethylene)-1 H -pyrrol-2(5 H )-ones; synthesis and mechanistic study
Published in Tetrahedron (01-09-2016)Get full text
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10
Pirroloindolonok szintézise és felhasználási lehetőségei
Published 01-01-2018“…Tf2O-vzise és hasznosíthatósági lehetőségeik körében végeztem. Célom egyrészt a vegyületcsalád képviselőinek szintézisére hatékony és általánosan alkalmazható…”
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Dissertation