Search Results - "Heredia, Jeremiah D"

Mapping Interaction Sites on Human Chemokine Receptors by Deep Mutational Scanning by Heredia, Jeremiah D, Park, Jihye, Brubaker, Riley J, Szymanski, Steven K, Gill, Kevin S, Procko, Erik

“…Chemokine receptors CXCR4 and CCR5 regulate WBC trafficking and are engaged by the HIV-1 envelope glycoprotein gp120 during infection. We combine a selection…”
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Conformational Engineering of HIV-1 Env Based on Mutational Tolerance in the CD4 and PG16 Bound States by Heredia, Jeremiah D, Park, Jihye, Choi, Hannah, Gill, Kevin S, Procko, Erik

“…HIV-1 infection is initiated by viral Env engaging the host receptor CD4, triggering Env to transition from a "closed" to "open" conformation during the early…”
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Multiple mechanisms of self-association of chemokine receptors CXCR4 and CCR5 demonstrated by deep mutagenesis by Gill, Kevin S., Mehta, Kritika, Heredia, Jeremiah D., Krishnamurthy, Vishnu V., Zhang, Kai, Procko, Erik

“…Chemokine receptors are members of the rhodopsin-like class A GPCRs whose signaling through G proteins drives the directional movement of cells in response to…”
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