Search Results - "Herder, Christian"
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Impact of early psychosocial factors (childhood socioeconomic factors and adversities) on future risk of type 2 diabetes, metabolic disturbances and obesity: a systematic review
Published in BMC public health (01-09-2010)“…Psychological factors and socioeconomic status (SES) have a notable impact on health disparities, including type 2 diabetes risk. However, the link between…”
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Relationship between Adipocyte Size and Adipokine Expression and Secretion
Published in The journal of clinical endocrinology and metabolism (01-03-2007)“…Context: Adipocytes are known to release a variety of factors that may contribute to the proinflammatory state characteristic for obesity. This secretory…”
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The IL-1 Pathway in Type 2 Diabetes and Cardiovascular Complications
Published in Trends in endocrinology and metabolism (01-10-2015)“…Patients with type 2 diabetes (T2D) exhibit chronic activation of the innate immune system in pancreatic islets, in insulin-sensitive tissues, and at sites of…”
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Specific Hepatic Sphingolipids Relate to Insulin Resistance, Oxidative Stress, and Inflammation in Nonalcoholic Steatohepatitis
Published in Diabetes care (01-06-2018)“…Insulin resistance and nonalcoholic fatty liver (NAFL) disease have been linked to several lipid metabolites in animals, but their role in humans remains…”
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Prediabetes: a high-risk state for diabetes development
Published in The Lancet (British edition) (16-06-2012)“…Summary Prediabetes (intermediate hyperglycaemia) is a high-risk state for diabetes that is defined by glycaemic variables that are higher than normal, but…”
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Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans
Published in Proceedings of the National Academy of Sciences - PNAS (01-07-2014)“…Muscle insulin resistance is a key feature of obesity and type 2 diabetes and is strongly associated with increased intramyocellular lipid content and…”
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Empagliflozin Effectively Lowers Liver Fat Content in Well-Controlled Type 2 Diabetes: A Randomized, Double-Blind, Phase 4, Placebo-Controlled Trial
Published in Diabetes care (01-02-2020)“…To evaluate whether the sodium-glucose cotransporter 2 inhibitor empagliflozin (EMPA) reduces liver fat content (LFC) in recent-onset and metabolically…”
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Traffic-Related Air Pollution and Incident Type 2 Diabetes: Results from the SALIA Cohort Study
Published in Environmental health perspectives (01-09-2010)“…Background: Cross-sectional and ecological studies indicate that air pollution may be a risk factor for type 2 diabetes, but prospective data are lacking…”
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Acute dietary fat intake initiates alterations in energy metabolism and insulin resistance
Published in The Journal of clinical investigation (01-02-2017)“…Dietary intake of saturated fat is a likely contributor to nonalcoholic fatty liver disease (NAFLD) and insulin resistance, but the mechanisms that initiate…”
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All-source and source-specific air pollution and 10-year diabetes Incidence: Total effect and mediation analyses in the Heinz Nixdorf recall study
Published in Environment international (01-03-2020)“…•All-source AP exposure associated with DM incidence.•Traffic-specific AP exposure shows strongest association with DM.•Possible mediation through decreased…”
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Effects of coffee consumption on subclinical inflammation and other risk factors for type 2 diabetes: a clinical trial
Published in The American journal of clinical nutrition (01-04-2010)“…BACKGROUND: Coffee consumption is associated with a decreased risk of type 2 diabetes. Suggested mechanisms underlying the association have included…”
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The association between dairy intake in adolescents on inflammation and risk markers of type 2 diabetes during young adulthood: results of the DONALD study
Published in Public health nutrition (13-03-2024)“…The aim of this analysis was to investigate whether habitual intake of total dairy (TD) or different dairy types (liquid, solid, fermented, non-fermented,…”
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Dietary palmitate and oleate differently modulate insulin sensitivity in human skeletal muscle
Published in Diabetologia (01-02-2022)“…Aims/hypothesis Energy-dense nutrition generally induces insulin resistance, but dietary composition may differently affect glucose metabolism. This study…”
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Perceived risk of diabetes seriously underestimates actual diabetes risk: The KORA FF4 study
Published in PloS one (31-01-2017)“…Early detection of diabetes and prediabetic states is beneficial for patients, but may be delayed by patients´ being overly optimistic about their own health…”
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Developmental trajectories of body mass index from childhood into late adolescence and subsequent late adolescence-young adulthood cardiometabolic risk markers
Published in Cardiovascular diabetology (19-01-2019)“…Reports on body mass index (BMI) trajectories from childhood into late adolescence, their determinants, and subsequent cardiometabolic risk markers,…”
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Type 2 diabetes across populations of different ancestry: deconstructing the genomic landscape
Published in Signal transduction and targeted therapy (09-09-2024)Get full text
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Dynamic changes of muscle insulin sensitivity after metabolic surgery
Published in Nature communications (13-09-2019)“…The mechanisms underlying improved insulin sensitivity after surgically-induced weight loss are still unclear. We monitored skeletal muscle metabolism in obese…”
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Chronic air pollution-induced subclinical airway inflammation and polygenic susceptibility
Published in Respiratory research (23-09-2022)“…Abstract Background Air pollutants can activate low-grade subclinical inflammation which further impairs respiratory health. We aimed to investigate the role…”
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Air pollution and diabetes-related biomarkers in non-diabetic adults: A pathway to impaired glucose metabolism?
Published in Environment international (01-03-2019)“…While prior studies have linked air pollution (AP) to diabetes prevalence and incidence, few have investigated whether AP exposure is also associated with…”
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Association between DNA Methylation in Whole Blood and Measures of Glucose Metabolism: KORA F4 Study
Published in PloS one (28-03-2016)“…Epigenetic regulation has been postulated to affect glucose metabolism, insulin sensitivity and the risk of type 2 diabetes. Therefore, we performed an…”
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