Search Results - "Herbreteau, Cécile H"

Description and characterization of a novel live-attenuated tri-segmented Machupo virus in Guinea pigs by Zaza, Amélie D, Herbreteau, Cécile H, Peyrefitte, Christophe N

“…Machupo virus (MACV) is a member of the Mammarenavirus genus, Arenaviridae family and is the etiologic agent of Bolivian hemorrhagic fever, which causes small…”
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Mammarenaviruses deleted from their Z gene are replicative and produce an infectious progeny in BHK-21 cells by Zaza, Amélie D., Herbreteau, Cécile H., Peyrefitte, Christophe N., Emonet, Sébastien F.

“…Mammarenaviruses bud out of infected cells via the recruitment of the endosomal sorting complex required for transport through late domain motifs localized…”
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Lentiviral RNAs can use different mechanisms for translation initiation by Ricci, Emiliano P, Soto Rifo, Ricardo, Herbreteau, Cécile H, Decimo, Didier, Ohlmann, Théophile

“…The full-length genomic RNA of lentiviruses can be translated to produce proteins and incorporated as genomic RNA in the viral particle. Interestingly, both…”
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In Vitro Characterization and In Vivo Effectiveness of Ebola Virus Specific Equine Polyclonal F(ab′)2 by Racine, Trina, Denizot, Mélanie, Pannetier, Delphine, Nguyen, Ludovic, Pasquier, Anaïs, Raoul, Hervé, Saluzzo, Jean-François, Kobinger, Gary, Veas, Francisco, Herbreteau, Cécile H

“…Abstract There is no vaccine or approved therapy against lethal Ebola virus (EBOV). We investigated a proven technology platform to produce polyclonal IgG…”
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Safety, potential efficacy, and pharmacokinetics of specific polyclonal immunoglobulin F(ab')2 fragments against avian influenza A (H5N1) in healthy volunteers: a single-centre, randomised, double-blind, placebo-controlled, phase 1 study by Bal, Céline, PharmD, Herbreteau, Cécile H, Dr, Buchy, Philippe, MD, Rith, Sareth, PharmD, Zaid, Masliza, MMed, Kristanto, William, MMed, Han, Velda, MMed, Reynaud, Charlotte, PharmD, Granjard, Patrick, MD, Lépine, Bertrand, MD, Durand, Caroline, PharmD, Tambyah, Paul A, Prof

“…Summary Background Human infection with the avian influenza A H5N1 virus results in disease with a high fatality rate, against which antiviral treatments have…”
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HIV-2 genomic RNA contains a novel type of IRES located downstream of its initiation codon by Sargueil, Bruno, Ohlmann, Théophile, Herbreteau, Cécile H, Weill, Laure, Décimo, Didier, Prévôt, Déborah, Darlix, Jean-Luc

“…Eukaryotic translation initiation begins with assembly of a 48S ribosomal complex at the 5' cap structure or at an internal ribosomal entry segment (IRES). In…”
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Efficacy of a specific polyclonal equine F(ab')2 against avian influenza (H5N1) in ferrets: synergy with oseltamivir by Herbreteau, Cécile H, Denizot, Mélanie, Lowther, Suzanne, Riddell, Sarah, Frazer, Leah, Haining, Jessica, Arkinstall, Rachel, Payne, Jean, Harper, Jenni, Johnson, Dayna, Pasquier, Anaïs, Middleton, Deborah, Saluzzo, Jean-François

“…Current therapies against avian influenza (H5N1) provide limited clinical benefit. FBF-001 is a highly purified equine polyclonal immunoglobulin fragment…”
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In vitro expression of the HIV-2 genomic RNA is controlled by three distinct internal ribosome entry segments that are regulated by the HIV protease and the Gag polyprotein by Ricci, Emiliano P, Herbreteau, Cécile H, Decimo, Didier, Schaupp, Andreas, Datta, Siddhartha A K, Rein, Alan, Darlix, Jean-Luc, Ohlmann, Théophile

“…The HIV-2 genomic RNA serves both as a messenger for protein synthesis and as a genome for viral assembly and particle production. Our previous work has shown…”
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Characterization of a novel RNA-binding region of eIF4GI critical for ribosomal scanning by Prévôt, Déborah, Décimo, Didier, Herbreteau, Cécile H., Roux, Florence, Garin, Jérôme, Darlix, Jean-Luc, Ohlmann, Théophile

“…The eukaryotic translation initiation factor eIF4GI binds several proteins and acts as a scaffold to promote preinitiation complex formation on the mRNA…”
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A new type of IRES within gag coding region recruits three initiation complexes on HIV-2 genomic RNA by Weill, Laure, James, Laurie, Ulryck, Nathalie, Chamond, Nathalie, Herbreteau, Cecile H, Ohlmann, Theophile, Sargueil, Bruno

“…Genomic RNA of primate lentiviruses serves both as an mRNA that encodes Gag and Gag-Pol polyproteins and as a propagated genome. Translation of this RNA is…”
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Past, present and future therapeutic and prophylactic strategies against arenaviruses responsible of human hemorrhagic fever by Zaza, Amélie D, Herbreteau, Cécile H, Peyrefitte, Christophe N, Emonet, Sébastien F

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Safety, potential efficacy, and pharmacokinetics of specific polyclonal immunoglobulin F(ab')2fragments against avian influenza A (H5N1) in healthy volunteers: a single-centre, randomised, double-blind, placebo-controlled, phase 1 study by Bal, Céline, Herbreteau, Cécile H, Buchy, Philippe, Rith, Sareth, Zaid, Masliza, Kristanto, William, Han, Velda, Reynaud, Charlotte, Granjard, Patrick, Lépine, Bertrand, Durand, Caroline, Tambyah, Paul A

“…Human infection with the avian influenza A H5N1 virus results in disease with a high fatality rate, against which antiviral treatments have limited efficacy…”
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Efficacy of a specific polyclonal equine F(ab') by Herbreteau, Cécile H, Denizot, Mélanie, Lowther, Suzanne, Riddell, Sarah, Frazer, Leah, Haining, Jessica, Arkinstall, Rachel, Payne, Jean, Harper, Jenni, Johnson, Dayna, Pasquier, Anaïs, Middleton, Deborah, Saluzzo, Jean-François

“…Current therapies against avian influenza (H5N1) provide limited clinical benefit. FBF-001 is a highly purified equine polyclonal immunoglobulin fragment…”
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Efficacy of a specific polyclonal equine F(ab') sub( 2) against avian influenza (H5N1) in ferrets: synergy with oseltamivir by Herbreteau, Cecile H, Denizot, Melanie, Lowther, Suzanne, Riddell, Sarah, Frazer, Leah, Haining, Jessica, Arkinstall, Rachel, Payne, Jean, Harper, Jenni, Johnson, Dayna, Pasquier, Anais, Middleton, Deborah, Saluzzo, Jean-Francois

“…Current therapies against avian influenza (H5N1) provide limited clinical benefit. FBF-001 is a highly purified equine polyclonal immunoglobulin fragment…”
Get full text