Search Results - "Herbert P. Schweizer"

The BpeAB-OprB Efflux Pump of Burkholderia pseudomallei 1026b Does Not Play a Role in Quorum Sensing, Virulence Factor Production, or Extrusion of Aminoglycosides but Is a Broad-Spectrum Drug Efflux System by MIMA, Takehiko, SCHWEIZER, Herbert P

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A 10-min method for preparation of highly electrocompetent Pseudomonas aeruginosa cells: Application for DNA fragment transfer between chromosomes and plasmid transformation by Choi, Kyoung-Hee, Kumar, Ayush, Schweizer, Herbert P.

“…A rapid microcentrifuge-based method is described for preparation of Pseudomonas aeruginosa electrocompetent cells with up to 10,000-fold increased…”
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Structural diversity of Burkholderia pseudomallei lipopolysaccharides affects innate immune signaling by Norris, Michael H, Schweizer, Herbert P, Tuanyok, Apichai

“…Burkholderia pseudomallei (Bp) causes the disease melioidosis. The main cause of mortality in this disease is septic shock triggered by the host responding to…”
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PBAD-Based Shuttle Vectors for Functional Analysis of Toxic and Highly Regulated Genes in Pseudomonas and Burkholderia spp. and Other Bacteria by Qiu, Dongru, Damron, F. Heath, Mima, Takehiko, Schweizer, Herbert P, Yu, Hongwei D

“…We report the construction of a series of Escherichia-Pseudomonas broad-host-range expression vectors utilizing the PBAD promoter and the araC regulator for…”
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Efflux pump-mediated drug resistance in Burkholderia by Podnecky, Nicole L, Rhodes, Katherine A, Schweizer, Herbert P

“…Several members of the genus Burkholderia are prominent pathogens. Infections caused by these bacteria are difficult to treat because of significant antibiotic…”
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Exploring Cefiderocol Resistance Mechanisms in Burkholderia pseudomallei by Hall, Carina M, Somprasong, Nawarat, Hagen, Johannah P, Nottingham, Roxanne, Sahl, Jason W, Webb, Jessica R, Mayo, Mark, Currie, Bart J, Podin, Yuwana, Wagner, David M, Keim, Paul, Schweizer, Herbert P

“…Cefiderocol is a siderophore cephalosporin designed mainly for treatment of infections caused by β-lactam and multidrug-resistant Gram-negative bacteria…”
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Workshop on treatment of and postexposure prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010 by Lipsitz, Rebecca, Garges, Susan, Aurigemma, Rosemarie, Baccam, Prasith, Blaney, David D, Cheng, Allen C, Currie, Bart J, Dance, David, Gee, Jay E, Larsen, Joseph, Limmathurotsakul, Direk, Morrow, Meredith G, Norton, Robert, O'Mara, Elizabeth, Peacock, Sharon J, Pesik, Nicki, Rogers, L Paige, Schweizer, Herbert P, Steinmetz, Ivo, Tan, Gladys, Tan, Patrick, Wiersinga, W Joost, Wuthiekanun, Vanaporn, Smith, Theresa L

“…The US Public Health Emergency Medical Countermeasures Enterprise convened subject matter experts at the 2010 HHS Burkholderia Workshop to develop consensus…”
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Antibiotic Resistance Markers in Burkholderia pseudomallei Strain Bp1651 Identified by Genome Sequence Analysis by Bugrysheva, Julia V, Sue, David, Gee, Jay E, Elrod, Mindy G, Hoffmaster, Alex R, Randall, Linnell B, Chirakul, Sunisa, Tuanyok, Apichai, Schweizer, Herbert P, Weigel, Linda M

“…Bp1651 is resistant to several classes of antibiotics that are usually effective for treatment of melioidosis, including tetracyclines, sulfonamides, and…”
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An improved method for rapid generation of unmarked Pseudomonas aeruginosa deletion mutants by Choi, Kyoung-Hee, Schweizer, Herbert P

“…Traditional gene replacement procedures are still time-consuming. They usually necessitate cloning of the gene to be mutated, insertional inactivation of the…”
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The Burkholderia pseudomallei intracellular ‘TRANSITome’ by Heacock-Kang, Yun, McMillan, Ian A., Norris, Michael H., Sun, Zhenxin, Zarzycki-Siek, Jan, Bluhm, Andrew P., Cabanas, Darlene, Norton, Robert E., Ketheesan, Natkunam, Miller, Jeff F., Schweizer, Herbert P., Hoang, Tung T.

“…Prokaryotic cell transcriptomics has been limited to mixed or sub-population dynamics and individual cells within heterogeneous populations, which has hampered…”
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The BpeEF-OprC Efflux Pump Is Responsible for Widespread Trimethoprim Resistance in Clinical and Environmental Burkholderia pseudomallei Isolates by PODNECKY, Nicole L, WUTHIEKANUN, Vanaporn, PEACOCK, Sharon J, SCHWEIZER, Herbert P

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Identification and Characterization of TriABC-OpmH, a Triclosan Efflux Pump of Pseudomonas aeruginosa Requiring Two Membrane Fusion Proteins by Mima, Takehiko, Joshi, Swati, Gomez-Escalada, Margarita, Schweizer, Herbert P.

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Versatile Dual-Technology System for Markerless Allele Replacement in Burkholderia pseudomallei by López, Carolina M, Rholl, Drew A, Trunck, Lily A, Schweizer, Herbert P

“…Burkholderia pseudomallei is the etiologic agent of melioidosis, a rare but serious tropical disease. In the United States, genetic research with this select…”
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Genetic Tools for Select-Agent-Compliant Manipulation of Burkholderia pseudomallei by Choi, Kyoung-Hee, Mima, Takehiko, Casart, Yveth, Rholl, Drew, Kumar, Ayush, Beacham, Ifor R, Schweizer, Herbert P

“…Because of Burkholderia pseudomallei's classification as a select agent in the United States, genetic manipulation of this bacterium is strictly regulated…”
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Burkholderia pseudomallei ΔpurM Mutant Is Avirulent in Immunocompetent and Immunodeficient Animals: Candidate Strain for Exclusion from Select-Agent Lists by Propst, Katie L, Mima, Takehiko, Choi, Kyoung-Hee, Dow, Steven W, Schweizer, Herbert P

“…Burkholderia pseudomallei causes the disease melioidosis in humans and is classified as a category B select agent. Research utilizing this pathogen is highly…”
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Evaluation of Delafloxacin against a Burkholderia pseudomallei Efflux Mutant Panel by McCurdy, Sandra P, Somprasong, Nawarat, Schweizer, Herbert P

“…activities of delafloxacin and ciprofloxacin were evaluated against Burkholderia pseudomallei mutants expressing or lacking defined resistance-nodulation-cell…”
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Molecular determinants of Burkholderia pseudomallei BpeEF-OprC efflux pump expression by Rhodes, Katherine A, Somprasong, Nawarat, Podnecky, Nicole L, Mima, Takehiko, Chirakul, Sunisa, Schweizer, Herbert P

“…Burkholderia pseudomallei, the cause of melioidosis, is intrinsically resistant to many antibiotics. Acquired multidrug resistance, including resistance to…”
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Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholderia pseudomallei by Chantratita, Narisara, Rholl, Drew A, Sim, Bernice, Wuthiekanun, Vanaporn, Limmathurotsakul, Direk, Amornchai, Premjit, Thanwisai, Aunchalee, Chua, Hui Hoon, Ooi, Wen Fong, Holden, Matthew T. G, Day, Nicholas P, Tan, Patrick, Schweizer, Herbert P, Peacock, Sharon J

“…Known mechanisms of resistance to β-lactam antibiotics include β-lactamase expression, altered drug target, decreased bacterial permeability, and increased…”
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Construction of Mobilizable Mini-Tn7 Vectors for Bioluminescent Detection of Gram-Negative Bacteria and Single-Copy Promoter lux Reporter Analysis by HEATH DAMRON, F, MCKENNEY, Elizabeth S, BARBIER, Mariette, LIECHTI, George W, SCHWEIZER, Herbert P, GOLDBERG, Joanna B

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Pseudomonas aeruginosa Thiol Peroxidase Protects against Hydrogen Peroxide Toxicity and Displays Atypical Patterns of Gene Regulation by Somprasong, Nawarat, Jittawuttipoka, Thichakorn, Duang-nkern, Jintana, Romsang, Adisak, Chaiyen, Pimchai, Schweizer, Herbert P, Vattanaviboon, Paiboon, Mongkolsuk, Skorn

“…The Pseudomonas aeruginosa PAO1 thiol peroxidase homolog (Tpx) belongs to a family of enzymes implicated in the removal of toxic peroxides. We have shown the…”
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