Search Results - "Herbert, J"
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1
Mussel adhesion - essential footwork
Published in Journal of experimental biology (15-02-2017)“…Robust adhesion to wet, salt-encrusted, corroded and slimy surfaces has been an essential adaptation in the life histories of sessile marine organisms for…”
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2
Cortisol and depression: three questions for psychiatry
Published in Psychological medicine (01-03-2013)“…Cortisol plays a multifaceted role in major depression disorder (MDD). Diurnal rhythms are disturbed, there is increased resistance to the feedback action of…”
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3
PDK4 dictates metabolic resistance to ferroptosis by suppressing pyruvate oxidation and fatty acid synthesis
Published in Cell reports (Cambridge) (23-02-2021)“…Although induction of ferroptosis, an iron-dependent form of non-apoptotic cell death, has emerged as an anticancer strategy, the metabolic basis of…”
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4
The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity
Published in Cell reports (Cambridge) (15-08-2017)“…Ferroptosis is a form of regulated cell death that may facilitate the selective elimination of tumor cells. The tumor suppressor p53 (TP53) has been…”
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5
Autophagy promotes ferroptosis by degradation of ferritin
Published in Autophagy (02-08-2016)“…Macroautophagy/autophagy is an evolutionarily conserved degradation pathway that maintains homeostasis. Ferroptosis, a novel form of regulated cell death, is…”
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6
How Plant Root Exudates Shape the Nitrogen Cycle
Published in Trends in plant science (01-08-2017)“…Although the global nitrogen (N) cycle is largely driven by soil microbes, plant root exudates can profoundly modify soil microbial communities and influence…”
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HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells
Published in Cancer research (Chicago, Ill.) (15-04-2017)“…Ferroptosis is a form of regulated cell death driven by oxidative injury promoting lipid peroxidation, although detailed molecular regulators are largely…”
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High-mobility group box 1, oxidative stress, and disease
Published in Antioxidants & redox signaling (01-04-2011)“…Oxidative stress and associated reactive oxygen species can modify lipids, proteins, carbohydrates, and nucleic acids, and induce the mitochondrial…”
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9
Racialization and racialization research
Published in Ethnic and racial studies (19-02-2017)“…This paper advocates a greater emphasis on racialization research, and consists of observations and research questions that could add to our understanding of…”
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10
Toughening elastomers using mussel-inspired iron-catechol complexes
Published in Science (American Association for the Advancement of Science) (27-10-2017)“…Materials often exhibit a trade-off between stiffness and extensibility; for example, strengthening elastomers by increasing their cross-link density leads to…”
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11
High mobility group protein B1 controls liver cancer initiation through yes‐associated protein ‐dependent aerobic glycolysis
Published in Hepatology (Baltimore, Md.) (01-05-2018)“…Emerging studies have suggested that the Hippo pathway is involved in the tumorigenesis of hepatocellular carcinoma (HCC). However, the key regulator of the…”
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12
The multifunctional protein HMGB1: 50 years of discovery
Published in Nature reviews. Immunology (01-12-2023)“…Fifty years since the initial discovery of HMGB1 in 1973 as a structural protein of chromatin, HMGB1 is now known to regulate diverse biological processes…”
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13
HMGB1 in Cancer: Good, Bad, or Both?
Published in Clinical cancer research (01-08-2013)“…Forty years ago, high mobility group box 1 (HMGB1) was discovered in calf thymus and named according to its electrophoretic mobility in polyacrylamide gels…”
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14
The Role of Silicon in Higher Plants under Salinity and Drought Stress
Published in Frontiers in plant science (18-07-2016)“…Although deemed a "non-essential" mineral nutrient, silicon (Si) is clearly beneficial to plant growth and development, particularly under stress conditions,…”
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15
Endogenous HMGB1 regulates autophagy
Published in The Journal of cell biology (06-09-2010)“…Autophagy clears long-lived proteins and dysfunctional organelles and generates substrates for adenosine triphosphate production during periods of starvation…”
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16
Surface chemistry Mussel power
Published in Nature materials (01-01-2008)“…Despite the development of numerous pre-adhesive treatments in an attempt to put a more reactive face on uncooperative surfaces, no general strategy has been…”
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Cell death in pancreatic cancer: from pathogenesis to therapy
Published in Nature reviews. Gastroenterology & hepatology (01-11-2021)“…Pancreatic cancer is a devastating gastrointestinal cancer characterized by late diagnosis, limited treatment success and dismal prognosis. Exocrine tumours…”
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500 Minimally Invasive Robotic Pancreatoduodenectomies: One Decade of Optimizing Performance
Published in Annals of surgery (01-05-2021)“…OBJECTIVES:This study aims to present the outcomes of our decade-long experience of robotic pancreatoduodenectomy and provide insights into successful program…”
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Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma
Published in Gastroenterology (New York, N.Y. 1943) (01-11-2017)“…Induction of nonapoptotic cell death could be an approach to eliminate apoptosis-resistant tumors. We investigated necroptosis-based therapies in mouse models…”
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Ferroptotic damage promotes pancreatic tumorigenesis through a TMEM173/STING-dependent DNA sensor pathway
Published in Nature communications (11-12-2020)“…Ferroptosis is a more recently recognized form of cell death that relies on iron-mediated oxidative damage. Here, we evaluate the impact of high-iron diets or…”
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