Search Results - "Herault, Olivier"

Hypoxia and Hypoxia-Inducible Factors in Leukemias by Deynoux, Margaux, Sunter, Nicola, Hérault, Olivier, Mazurier, Frédéric

“…Despite huge improvements in the treatment of leukemia, the percentage of patients suffering relapse still remains significant. Relapse most often results from…”
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A comparative study of the capacity of mesenchymal stromal cell lines to form spheroids by Deynoux, Margaux, Sunter, Nicola, Ducrocq, Elfi, Dakik, Hassan, Guibon, Roseline, Burlaud-Gaillard, Julien, Brisson, Lucie, Rouleux-Bonnin, Florence, le Nail, Louis-Romée, Hérault, Olivier, Domenech, Jorge, Roingeard, Philippe, Fromont, Gaëlle, Mazurier, Frédéric, Asakura, Atsushi

“…Mesenchymal stem cells (MSC)-spheroid models favor maintenance of stemness, ex vivo expansion and transplantation efficacy. Spheroids may also be considered as…”
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Disruption of gap junctions attenuates acute myeloid leukemia chemoresistance induced by bone marrow mesenchymal stromal cells by Kouzi, Farah, Zibara, Kazem, Bourgeais, Jerome, Picou, Frederic, Gallay, Nathalie, Brossaud, Julie, Dakik, Hassan, Roux, Benjamin, Hamard, Sophie, Le Nail, Louis-Romee, Hleihel, Rita, Foucault, Amelie, Ravalet, Noemie, Rouleux-Bonnin, Florence, Gouilleux, Fabrice, Mazurier, Frederic, Bene, Marie C., Akl, Haidar, Gyan, Emmanuel, Domenech, Jorge, El-Sabban, Marwan, Herault, Olivier

“…The bone marrow (BM) niche impacts the progression of acute myeloid leukemia (AML) by favoring the chemoresistance of AML cells. Intimate interactions between…”
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The hepatokine FGF21 stopped lipogenesis and reduced testosterone production in mLTC-1 Leydig Cell Line by Bourdon, Guillaume, Chevaleyre, Claire, Estienne, Anthony, Péchoux, Christine, Bourgeais, Jérôme, Hérault, Olivier, Ba, Mouhamadou, Ramé, Christelle, Dupont, Joëlle, Ducluzeau, Pierre-Henri, Froment, Pascal

“…Beyond their link to metabolic issues like type 2 diabetes, factors like lifestyle, environment, and excess weight may also influence fertility. Fibroblast…”
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Occupational pesticide exposure increases risk of acute myeloid leukemia: a meta-analysis of case–control studies including 3,955 cases and 9,948 controls by Foucault, Amelie, Vallet, Nicolas, Ravalet, Noemie, Picou, Frederic, Bene, Marie C., Gyan, Emmanuel, Herault, Olivier

“…The impact of pesticides on health is a major public health concern. A higher risk to develop chronic lymphoid malignancies has been demonstrated to be…”
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Letter to the editor with regard to the article entitled “Automated leukocyte parameters are useful in the assessment of myelodysplastic syndromes” by Eveillard, Marion, Béné, Marie C., Hérault, Olivier

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Flow cytometric quantification of all phases of the cell cycle and apoptosis in a two-color fluorescence plot by Vignon, Christine, Debeissat, Christelle, Georget, Marie-Thérèse, Bouscary, Didier, Gyan, Emmanuel, Rosset, Philippe, Herault, Olivier

“…An optimal technology for cell cycle analysis would allow the concomitant measurement of apoptosis, G0, G1, S, G2 and M phases in combination with cell surface…”
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CXCR4/CXCL12 axis counteracts hematopoietic stem cell exhaustion through selective protection against oxidative stress by Zhang, Yanyan, Dépond, Mallorie, He, Liang, Foudi, Adlen, Kwarteng, Edward Owusu, Lauret, Evelyne, Plo, Isabelle, Desterke, Christophe, Dessen, Philippe, Fujii, Nobutaka, Opolon, Paule, Herault, Olivier, Solary, Eric, Vainchenker, William, Joulin, Virginie, Louache, Fawzia, Wittner, Monika

“…Hematopoietic stem cells (HSCs) undergo self-renewal to maintain hematopoietic homeostasis for lifetime, which is regulated by the bone marrow (BM)…”
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n-3 Polyunsaturated fatty acids induce acute myeloid leukemia cell death associated with mitochondrial glycolytic switch and Nrf2 pathway activation by Picou, Frédéric, Debeissat, Christelle, Bourgeais, Jérôme, Gallay, Nathalie, Ferrié, Elise, Foucault, Amélie, Ravalet, Noémie, Maciejewski, Aurore, Vallet, Nicolas, Ducrocq, Elfi, Haddaoui, Lamya, Domenech, Jorge, Hérault, Olivier, Gyan, Emmanuel

“…[Display omitted] Acute Myeloid Leukemia (AML) remains a therapeutic challenge and improvements in chemotherapy are needed. n-3 polyunsaturated fatty acids…”
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Chronic IL-15 Stimulation and Impaired mTOR Signaling and Metabolism in Natural Killer Cells During Acute Myeloid Leukemia by Bou-Tayeh, Berna, Laletin, Vladimir, Salem, Nassim, Just-Landi, Sylvaine, Fares, Joanna, Leblanc, Raphael, Balzano, Marielle, Kerdiles, Yann M, Bidaut, Ghislain, Hérault, Olivier, Olive, Daniel, Aurrand-Lions, Michel, Walzer, Thierry, Nunès, Jacques A, Fauriat, Cyril

“…Natural Killer (NK) cells are potent anti-leukemic immune effectors. However, they display multiple defects in acute myeloid leukemia (AML) patients leading to…”
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Comparison of Tumor- and Bone Marrow-Derived Mesenchymal Stromal/Stem Cells from Patients with High-Grade Osteosarcoma by Le Nail, Louis-Romée, Brennan, Meadhbh, Rosset, Philippe, Deschaseaux, Frédéric, Piloquet, Philippe, Pichon, Olivier, Le Caignec, Cédric, Crenn, Vincent, Layrolle, Pierre, Hérault, Olivier, De Pinieux, Gonzague, Trichet, Valérie

“…Osteosarcoma (OS) is suspected to originate from dysfunctional mesenchymal stromal/stem cells (MSC). We sought to identify OS-derived cells (OSDC) with…”
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No survival improvement in patients with high‐risk multiple myeloma harbouring del(17p) and/or t(4;14) over the two past decades by Chalopin, Thomas, Vallet, Nicolas, Theisen, Olivier, Ochmann, Marlène, Tiab, Mourad, Godmer, Pascal, Barin, Carole, Hérault, Olivier, Gyan, Emmanuel, Le Gouill, Steven, Avet‐Loiseau, Hervé, Benboubker, Lotfi, Moreau, Philippe, Touzeau, Cyrille

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Curcumin and NCLX inhibitors share anti-tumoral mechanisms in microsatellite-instability-driven colorectal cancer by Guéguinou, Maxime, Ibrahim, Sajida, Bourgeais, Jérôme, Robert, Alison, Pathak, Trayambak, Zhang, Xuexin, Crottès, David, Dupuy, Jacques, Ternant, David, Monbet, Valérie, Guibon, Roseline, Flores-Romero, Hector, Lefèvre, Antoine, Lerondel, Stéphanie, Le Pape, Alain, Dumas, Jean-François, Frank, Philippe G., Girault, Alban, Chautard, Romain, Guéraud, Françoise, García-Sáez, Ana J., Ouaissi, Mehdi, Emond, Patrick, Sire, Olivier, Hérault, Olivier, Fromont-Hankard, Gaëlle, Vandier, Christophe, Tougeron, David, Trebak, Mohamed, Raoul, William, Lecomte, Thierry

“…Background and aims Recent evidences highlight a role of the mitochondria calcium homeostasis in the development of colorectal cancer (CRC). To overcome…”
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Multipotential Mesenchymal Stem Cells Are Mobilized into Peripheral Blood by Hypoxia by Rochefort, Gaël Y., Delorme, Bruno, Lopez, Adriana, Hérault, Olivier, Bonnet, Pierre, Charbord, Pierre, Eder, Véronique, Domenech, Jorge

“…MSCs constitute a population of multipotential cells giving rise to adipocytes, osteoblasts, chondrocytes, and vascular‐smooth muscle‐like hematopoietic…”
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Specific changes of erythroid regulators and hepcidin in patients infected by SARS-COV-2 by Delaye, Jean-Baptiste, Alarcan, Hugo, Vallet, Nicolas, Veyrat-Durebex, Charlotte, Bernard, Louis, Hérault, Olivier, Ropert, Martine, Marlet, Julien, Gyan, Emmanuel, Andres, Christian, Blasco, Hélène, Piver, Eric

“…Iron metabolism is tightly linked to infectious and inflammatory signals through hepcidin synthesis. To date, iron homeostasis during SARS-CoV-2 infection has…”
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Dual Inhibition of PI3K and mTORC1/2 Signaling by NVP-BEZ235 as a New Therapeutic Strategy for Acute Myeloid Leukemia by CHAPUIS, Nicolas, TAMBURINI, Jerome, MAIRA, Sauveur-Michel, IFRAH, Norbert, DREYFUS, François, HERAULT, Olivier, LACOMBE, Catherine, MAYEUX, Patrick, BOUSCARY, Didier, GREEN, Alexa S, VIGNON, Christine, BARDET, Valerie, NEYRET, Aymeric, PANNETIER, Melanie, WILLEMS, Lise, PARK, Sophie, MACONE, Alexandre

“…The growth and survival of acute myeloid leukemia (AML) cells are enhanced by the deregulation of signaling pathways such as phosphoinositide 3-kinase…”
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Alteration Analysis of Bone Marrow Mesenchymal Stromal Cells from De Novo Acute Myeloid Leukemia Patients at Diagnosis by Desbourdes, Laura, Javary, Joaquim, Charbonnier, Thomas, Ishac, Nicole, Bourgeais, Jerome, Iltis, Aurore, Chomel, Jean-Claude, Turhan, Ali, Guilloton, Fabien, Tarte, Karin, Demattei, Marie-Veronique, Ducrocq, Elfi, Rouleux-Bonnin, Florence, Gyan, Emmanuel, Hérault, Olivier, Domenech, Jorge

“…Bone marrow (BM)-derived mesenchymal stromal cells (MSCs) frequently display alterations in several hematologic disorders, such as acute lymphoid leukemia,…”
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The Antioxidant TEMPOL Protects Human Hematopoietic Stem Cells From Culture-Mediated Loss of Functions by Henry, Elia, Picou, Frédéric, Barroca, Vilma, Dechamps, Nathalie, Sobrino, Steicy, Six, Emmanuelle, Gobeaux, Camille, Auberger, Patrick, Hérault, Olivier, Pflumio, Françoise, Arcangeli, Marie-Laure

“…Abstract In a steady state, hematopoietic stem cells (HSC) exhibit very low levels of reactive oxygen species (ROS). Upon stress, HSC get activated and enter…”
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Cyclin D1 unbalances the redox status controlling cell adhesion, migration, and drug resistance in myeloma cells by Bustany, Sophie, Bourgeais, Jérôme, Tchakarska, Guergana, Body, Simon, Hérault, Olivier, Gouilleux, Fabrice, Sola, Brigitte

“…The interactions of multiple myeloma (MM) cells with their microenvironment are crucial for pathogenesis. MM cells could interact differentially with their…”
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Deep Learning-Based Blood Abnormalities Detection as a Tool for VEXAS Syndrome Screening by De Almeida Braga, Cédric, Bauvais, Maxence, Sujobert, Pierre, Heiblig, Maël, Jullien, Maxime, Le Calvez, Baptiste, Richard, Camille, Le Roc'h, Valentin, Rault, Emmanuelle, Hérault, Olivier, Peterlin, Pierre, Garnier, Alice, Chevallier, Patrice, Bouzy, Simon, Le Bris, Yannick, Néel, Antoine, Graveleau, Julie, Kosmider, Olivier, Paul-Gilloteaux, Perrine, Normand, Nicolas, Eveillard, Marion

“…VEXAS is a syndrome described in 2020, caused by mutations of the UBA1 gene, and displaying a large pleomorphic array of clinical and hematological features…”
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