Search Results - "Heraud, Audrey"
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Human peripheral blood mononuclear cells display a temporal evolving inflammatory profile after myocardial infarction and modify myocardial fibroblasts phenotype
Published in Scientific reports (05-10-2023)“…Pathophysiological response after acute myocardial infarction (AMI) is described as a three-stage model involving temporal phenotypic modifications of both…”
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2
P2x4 receptor promotes mammary cancer progression by sustaining autophagy and associated mesenchymal transition
Published in Oncogene (20-05-2022)“…Metastatic progression is a major burden for breast cancer patients and is associated with the ability of cancer cells to overcome stressful conditions, such…”
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3
Tocilizumab Contributes to the Inflammatory Status of Mature Dendritic Cells through Interleukin-6 Receptor Subunits Modulation
Published in Frontiers in immunology (16-08-2017)“…Tocilizumab, a humanized anti-IL-6 receptor α (IL-6Rα) is widely used in the treatment of a panel of pathologies such as adult and juvenile rheumatoid…”
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4
IL-2 phosphorylates STAT5 to drive IFN-γ production and activation of human dendritic cells
Published in The Journal of immunology (1950) (15-06-2014)“…Human dendritic cells (hDCs) produce IL-2 and express IL-2R α-chain (CD25), but the role of IL-2 in DC functions is not well defined. A recent study suggested…”
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5
PROM2 overexpression induces metastatic potential through epithelial‐to‐mesenchymal transition and ferroptosis resistance in human cancers
Published in Clinical and translational medicine (01-03-2024)“…Introduction Despite considerable therapeutic advances in the last 20 years, metastatic cancers remain a major cause of death. We previously identified…”
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The Voltage-Gated Sodium Channel Beta4 Subunit Maintains Epithelial Phenotype in Mammary Cells
Published in Cells (Basel, Switzerland) (29-06-2021)“…The gene, coding for the Na β4 subunit of voltage-gated sodium channels, was recently found to be expressed in normal epithelial cells and down-regulated in…”
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Stimulation of P2Y11 receptor modulates cardiac fibroblasts secretome toward immunomodulatory and protective roles after Hypoxia/Reoxygenation injury
Published in Journal of molecular and cellular cardiology (01-08-2018)“…Cardiac fibroblasts are important regulators of myocardial structure and function. Their implications in pathological processes such as Ischemia/Reperfusion…”
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Stimulation of P2Y11 receptor protects human cardiomyocytes against Hypoxia/Reoxygenation injury and involves PKCε signaling pathway
Published in Scientific reports (12-08-2019)“…Sterile inflammation is a key determinant of myocardial reperfusion injuries. It participates in infarct size determination in acute myocardial infarction and…”
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High extracellular sodium chloride concentrations induce resistance to LPS signal in human dendritic cells
Published in Cellular immunology (01-02-2023)“…•Human monocytes-derived dendritic cells submitted to extracellular Na + concentrations up to 200 mM remain viable and maintain the expression of specific DC…”
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