Recommendations for cerebrospinal fluid analysis

Diseases of the central nervous system (CNS) mean for the human organism a potentially dangerous situation. An investigation of cerebrospinal fluid (CSF) provides important information about a character of CNS impairment in the decision-making diagnostic and therapeutic algorithm. The authors presen...

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Bibliographic Details
Published in:	Folia microbiologica Vol. 64; no. 3; pp. 443 - 452
Main Authors:	Hepnar, D., Adam, P., Žáková, H., Krušina, M., Kalvach, P., Kasík, J., Karpowicz, I., Nasler, J., Bechyně, K., Fiala, T., Mamiňák, M., Malíková, I., Mareš, J., Šigut, V., Tokár, Z., Vránová, J.
Format:	Journal Article
Language:	English
Published:	Dordrecht Springer Netherlands 01-05-2019 Springer Nature B.V
Subjects:	Algorithms Applied Microbiology Biomedical and Life Sciences Central nervous system Cerebrospinal fluid Decision making Diagnostic systems Environmental Engineering/Biotechnology Immunology Laboratories Life Sciences Microbiology Review
Online Access:	Get full text
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Summary:	Diseases of the central nervous system (CNS) mean for the human organism a potentially dangerous situation. An investigation of cerebrospinal fluid (CSF) provides important information about a character of CNS impairment in the decision-making diagnostic and therapeutic algorithm. The authors present a brief overview of available cerebrospinal fluid assays, shortened indication criteria, a recommended algorithm of CSF assessment in different suspected diseases, and a view of the external quality system. The whole portfolio of obtainable CSF methodology is further subdivided according to the adequate choice into the first and inevitable basic routine panel, and following complicated analyses of highly specialized character. The basic panel is considered for standard laboratories, the complete specialized assessment should be provided by a super-consulting laboratory.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	0015-5632 1874-9356
DOI:	10.1007/s12223-018-0663-7