Cowpox with severe generalized eruption, Finland

Cowpox with severe generalized eruption, Finland

Cowpox with a severe, generalized eruption was diagnosed in an atopic 4-year-old girl by electron microscopy, virus isolation, polymerase chain reaction, and immunoglobulin (Ig) M and low-avidity IgG antibodies. The hemagglutinin gene of the isolate clustered with a Russian cowpox virus strain, and...

Full description

Saved in:
Bibliographic Details
Published in:Emerging infectious diseases Vol. 9; no. 11; pp. 1458 - 1461
Main Authors: Pelkonen, Paula M, Tarvainen, Kyllikki, Hynninen, Arja, Kallio, Eva R K, Henttonen, Keikki, Palva, Airi, Vaheri, Antti, Vapalahti, Olli
Format: Journal Article
Language:English
Published: United States U.S. National Center for Infectious Diseases 01-11-2003
Centers for Disease Control and Prevention
Subjects:
Animals
Antibodies, Viral - isolation & purification
Case studies
Child, Preschool
Cowpox
Cowpox - diagnosis
Cowpox - physiopathology
Cowpox virus
Cowpox virus - immunology
Cowpox virus - isolation & purification
diagnosis
Dispatch
DNA virus infections
epidemiology
Female
Finland
Health aspects
Humans
Orthopoxvirus
phylogeny
Vaccinia virus
Finland
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Cowpox with a severe, generalized eruption was diagnosed in an atopic 4-year-old girl by electron microscopy, virus isolation, polymerase chain reaction, and immunoglobulin (Ig) M and low-avidity IgG antibodies. The hemagglutinin gene of the isolate clustered with a Russian cowpox virus strain, and more distantly, with other cowpox and vaccinia virus strains. The patient's dog had orthopoxvirus-specific antibodies, indicating a possible transmission route. In Finnish wild rodents, orthopoxvirus seroprevalences were 0%-92%, in humans the seroprevalence was 100% in the age group >50, decreasing towards younger age groups.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ObjectType-Case Study-2
ObjectType-Feature-4
ObjectType-Report-1
ObjectType-Article-3
ISSN:1080-6040
1080-6059
DOI:10.3201/eid0911.020814