Search Results - "Henson, Sonal"

Access to ultra-long IgG CDRH3 bovine antibody sequences using short read sequencing technology by Oyola, Samuel O., Henson, Sonal P., Nzau, Benjamin, Kibwana, Elizabeth, Nene, Vishvanath

“…•Antibody discovery in African bovine breeds using a nested PCR strategy.•A methodology for sequencing of bovine ultra-long Ig VH transcripts using low error…”
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Deletion of the CD2v Gene from the Genome of ASFV-Kenya-IX-1033 Partially Reduces Virulence and Induces Protection in Pigs by Hemmink, Johanneke D, Khazalwa, Emmanuel M, Abkallo, Hussein M, Oduor, Bernard, Khayumbi, Jeremiah, Svitek, Nicholas, Henson, Sonal P, Blome, Sandra, Keil, Günther, Bishop, Richard P, Steinaa, Lucilla

“…Infection of pigs with the African swine fever virus (ASFV) leads to a devastating hemorrhagic disease with a high mortality of up to 100%. In this study, a…”
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A single-cell atlas of pig gastrulation as a resource for comparative embryology by Simpson, Luke, Strange, Andrew, Klisch, Doris, Kraunsoe, Sophie, Azami, Takuya, Goszczynski, Daniel, Le Minh, Triet, Planells, Benjamin, Holmes, Nadine, Sang, Fei, Henson, Sonal, Loose, Matthew, Nichols, Jennifer, Alberio, Ramiro

“…Cell-fate decisions during mammalian gastrulation are poorly understood outside of rodent embryos. The embryonic disc of pig embryos mirrors humans, making…”
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Development of a 3-transcript host expression assay to differentiate between viral and bacterial infections in pigs by Hjertner, Bernt, Lützelschwab, Claudia, Schieck, Elise, Nzau, Benjamin, Henson, Sonal, Sjölund, Marie, Fossum, Caroline, Magnusson, Ulf

“…Indiscriminate use of antibiotics to treat infections that are of viral origin contributes to unnecessary use which potentially may induce resistance in…”
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Contrasting patterns of longitudinal population dynamics and antimicrobial resistance mechanisms in two priority bacterial pathogens over 7 years in a single center by Ellington, Matthew J, Heinz, Eva, Wailan, Alexander M, Dorman, Matthew J, de Goffau, Marcus, Cain, Amy K, Henson, Sonal P, Gleadall, Nicholas, Boinett, Christine J, Dougan, Gordon, Brown, Nicholas M, Woodford, Neil, Parkhill, Julian, Török, M Estée, Peacock, Sharon J, Thomson, Nicholas R

“…Two of the most important pathogens contributing to the global rise in antimicrobial resistance (AMR) are Klebsiella pneumoniae and Enterobacter cloacae…”
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Molecular epidemiology of Klebsiella pneumoniae invasive infections over a decade at Kilifi County Hospital in Kenya by Henson, Sonal P., Boinett, Christine J., Ellington, Matthew J., Kagia, Ngure, Mwarumba, Salim, Nyongesa, Sammy, Mturi, Neema, Kariuki, Samuel, Scott, J. Anthony G., Thomson, Nicholas R., Morpeth, Susan C.

“…Multidrug resistant (MDR) Klebsiella pneumoniae is a common cause of nosocomial infections worldwide. Recent years have seen an explosion of resistance to…”
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The African Swine Fever Isolate ASFV-Kenya-IX-1033 Is Highly Virulent and Stable after Propagation in the Wild Boar Cell Line WSL by Hemmink, Johanneke D, Abkallo, Hussein M, Henson, Sonal P, Khazalwa, Emmanuel M, Oduor, Bernard, Lacasta, Anna, Okoth, Edward, Riitho, Victor, Fuchs, Walter, Bishop, Richard P, Steinaa, Lucilla

“…We describe the characterization of an African swine fever genotype IX virus (ASFV-Kenya-IX-1033), which was isolated from a domestic pig in western Kenya…”
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Rapid CRISPR/Cas9 Editing of Genotype IX African Swine Fever Virus Circulating in Eastern and Central Africa by Abkallo, Hussein M., Svitek, Nicholas, Oduor, Bernard, Awino, Elias, Henson, Sonal P., Oyola, Samuel O., Mwalimu, Stephen, Assad-Garcia, Nacrya, Fuchs, Walter, Vashee, Sanjay, Steinaa, Lucilla

“…African swine fever virus (ASFV) is the etiological agent of a contagious and fatal disease of domestic pigs that has significant economic consequences for the…”
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Complete Genome Sequencing and Comparative Phylogenomics of Nine African Swine Fever Virus (ASFV) Isolates of the Virulent East African p72 Genotype IX without Viral Sequence Enrichment by Domelevo Entfellner, Jean-Baka, Okoth, Edward Abworo, Onzere, Cynthia Kavulani, Upton, Chris, Njau, Emma Peter, Höper, Dirk, Henson, Sonal P, Oyola, Samuel O, Bochere, Edwina, Machuka, Eunice M, Bishop, Richard P

“…African swine fever virus (ASFV) is endemic to African wild pigs ( and ), in which viral infection is asymptomatic, and soft ticks. However, ASFV causes a…”
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Paternal undernutrition and overnutrition modify semen composition and preimplantation embryo developmental kinetics in mice by Morgan, Hannah L, Eid, Nader, Holmes, Nadine, Henson, Sonal, Wright, Victoria, Coveney, Clare, Winder, Catherine, O'Neil, Donna M, Dunn, Warwick B, Boocock, David J, Watkins, Adam J

“…The importance of parental diet in relation to eventual offspring health is increasing in prominence due to the increased frequency of parents of reproductive…”
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Sub-Optimal Paternal Diet at the Time of Mating Disrupts Maternal Adaptations to Pregnancy in the Late Gestation Mouse by Khoshkerdar, Afsaneh, Eid, Nader, Batra, Vipul, Baker, Nichola, Holmes, Nadine, Henson, Sonal, Sang, Fei, Wright, Victoria, McLaren, Jane, Shakesheff, Kevin, Woad, Kathryn J, Morgan, Hannah L, Watkins, Adam J

“…Pregnancy represents a stage during which maternal physiology and homeostatic regulation undergo dramatic change and adaptation. The fundamental purpose of…”
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High-resolution genotyping and mapping of recombination and gene conversion in the protozoan Theileria parva using whole genome sequencing by Henson, Sonal, Bishop, Richard P, Morzaria, Subhash, Spooner, Paul R, Pelle, Roger, Poveda, Lucy, Ebeling, Martin, Küng, Erich, Certa, Ulrich, Daubenberger, Claudia A, Qi, Weihong

“…Theileria parva is a tick-borne protozoan parasite, which causes East Coast Fever, a disease of cattle in sub-Saharan Africa. Like Plasmodium falciparum, the…”
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The genomes of three stocks comprising the most widely utilized live sporozoite Theileria parva vaccine exhibit very different degrees and patterns of sequence divergence by Norling, Martin, Bishop, Richard P, Pelle, Roger, Qi, Weihong, Henson, Sonal, Drábek, Elliott F, Tretina, Kyle, Odongo, David, Mwaura, Stephen, Njoroge, Thomas, Bongcam-Rudloff, Erik, Daubenberger, Claudia A, Silva, Joana C

“…There are no commercially available vaccines against human protozoan parasitic diseases, despite the success of vaccination-induced long-term protection…”
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Similar levels of diversity in the gene encoding the p67 sporozoite surface protein of Theileria parva are observed in blood samples from buffalo and cattle naturally infected from buffalo by Sitt, Tatjana, Henson, Sonal, Morrison, W. Ivan, Toye, Philip

“…•p67 sequence analysis was used to compare diversity in Theileria parva populations from cattle and buffalo.•T. parva isolated from cattle show similar levels…”
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Antibodies to in silico selected GPI-anchored Theileria parva proteins neutralize sporozoite infection in vitro by Nyagwange, James, Nene, Vishvanath, Mwalimu, Stephen, Henson, Sonal, Steinaa, Lucilla, Nzau, Benjamin, Tijhaar, Edwin, Pelle, Roger

“…•Six in silico selected GPI anchored proteins expressed in E. coli.•Murine antisera against four of expressed proteins neutralizes sporozoite infection.•Four…”
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High Resolution Analysis of Genes Transcribed In Ixodid Tick Tissues With Special Reference to Salivary Glands of the Brown Ear Tick, Rhipicephalus Appendiculatus by Henson, Sonal Prabhulal

“…R. appendiculatus, also known as the brown-ear tick, is the primary vector for T. parva, a protozoan parasite that causes East Coast Fever, a fatal…”
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