Search Results - "Henry, Stanley C"
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IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteins
Published in PLoS pathogens (01-06-2013)“…Interferon-inducible GTPases of the Immunity Related GTPase (IRG) and Guanylate Binding Protein (GBP) families provide resistance to intracellular pathogenic…”
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Irgm1-deficient mice exhibit Paneth cell abnormalities and increased susceptibility to acute intestinal inflammation
Published in American journal of physiology: Gastrointestinal and liver physiology (15-10-2013)“…Crohn's disease (CD) is a chronic, immune-mediated, inflammatory disorder of the intestine that has been linked to numerous susceptibility genes, including the…”
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Palmitoylation of the immunity related GTPase, Irgm1: impact on membrane localization and ability to promote mitochondrial fission
Published in PloS one (21-04-2014)“…The Immunity-Related GTPases (IRG) are a family of large GTPases that mediate innate immune responses. Irgm1 is particularly critical for immunity to bacteria…”
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Immunity-related GTPase M (IRGM) Proteins Influence the Localization of Guanylate-binding Protein 2 (GBP2) by Modulating Macroautophagy
Published in The Journal of biological chemistry (02-09-2011)“…The immunity-related GTPases (IRGs) are a family of proteins induced by interferon-γ that play a crucial role in innate resistance to intracellular pathogens…”
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Balance of Irgm protein activities determines IFN-γ-induced host defense
Published in Journal of leukocyte biology (01-05-2009)“…The immunity‐related GTPases (IRG), also known as p47 GTPases, are a family of proteins that are tightly regulated by IFNs at the transcriptional level and…”
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Impaired Macrophage Function Underscores Susceptibility to Salmonella in Mice Lacking Irgm1 (LRG-47)
Published in The Journal of immunology (1950) (15-11-2007)“…IRG proteins, or immunity-related GTPases (also known as p47 GTPases), are a group of IFN-regulated proteins that are highly expressed in response to…”
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Regulation of macrophage motility by Irgm1
Published in Journal of leukocyte biology (01-02-2010)“…Irgm1 controls macrophage motility by regulating the positioning of specific GKS IRG proteins to the plasma membrane, leading to altered Rac activity and actin…”
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p47 GTPases Regulate Toxoplasma gondii Survival in Activated Macrophages
Published in Infection and Immunity (01-06-2005)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Metabolic Alterations Contribute to Enhanced Inflammatory Cytokine Production in Irgm1-deficient Macrophages
Published in The Journal of biological chemistry (17-03-2017)“…The immunity-related GTPases (IRGs) are a family of proteins that are induced by interferon (IFN)-γ and play pivotal roles in immune and inflammatory…”
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Dendritic cell responses to early murine cytomegalovirus infection: subset functional specialization and differential regulation by interferon alpha/beta
Published in The Journal of experimental medicine (07-04-2003)“…Differentiation of dendritic cells (DCs) into particular subsets may act to shape innate and adaptive immune responses, but little is known about how this…”
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Nasal Peptide Vaccination Elicits CD8 Responses and Reduces Viral Burden after Challenge with Virulent Murine Cytomegalovirus
Published in Microbiology and immunology (01-01-2005)“…Infection of BALB/c mice with murine cytomegalovirus (MCMV) leads to CD8 cell responses to an immunodominant epitope YPHFMPTNL. We presented this epitope as a…”
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A lymphotoxin-IFN-beta axis essential for lymphocyte survival revealed during cytomegalovirus infection
Published in The Journal of immunology (1950) (01-06-2005)“…The importance of lymphotoxin (LT) betaR (LTbetaR) as a regulator of lymphoid organogenesis is well established, but its role in host defense has yet to be…”
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Behavioral characterization of P311 knockout mice
Published in Genes, brain and behavior (01-10-2008)“…P311 is an 8‐kDa protein that is expressed in many brain regions, particularly the hippocampus, cerebellum and olfactory lobes, and is under stringent…”
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Enhanced green fluorescent protein as a marker for localizing murine cytomegalovirus in acute and latent infection
Published in Journal of virological methods (01-09-2000)“…A recombinant murine cytomegalovirus (mCMV) that expresses enhanced green fluorescent protein (EGFP) under control of the native immediate-early 1/3 promoter…”
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Dendritic Cell Responses to Early Murine Cytomegalovirus Infection
Published in The Journal of experimental medicine (07-04-2003)“…Differentiation of dendritic cells (DCs) into particular subsets may act to shape innate and adaptive immune responses, but little is known about how this…”
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In vivo protein expression and immune responses generated by DNA vaccines expressing mycobacterial antigens fused with a reporter protein
Published in Vaccine (19-08-2002)“…We cloned six mycobacterial antigens into a mammalian expression vector as fusion proteins with the enhanced green fluorescent protein (EGFP). Plasmid DNA was…”
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Palmitoylation of the immunity related GTPase, Irgm 1: impact on membrane localization and ability to promote mitochondrial fission
Published in PloS one (01-04-2014)“…The Immunity-Related GTPases (IRG) are a family of large GTPases that mediate innate immune responses. Irgm1 is particularly critical for immunity to bacteria…”
Get full text
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IRG and GBP Host Resistance Factors Target Aberrant, "Non-self" Vacuoles Characterized by the Missing of "Self" IRGM Proteins: e1003414
Published in PLoS pathogens (01-06-2013)“…Interferon-inducible GTPases of the Immunity Related GTPase (IRG) and Guanylate Binding Protein (GBP) families provide resistance to intracellular pathogenic…”
Get full text
Journal Article -
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Palmitoylation of the Immunity Related GTPase, Irgm1: Impact on Membrane Localization and Ability to Promote Mitochondrial Fission: e95021
Published in PloS one (01-04-2014)“…The Immunity-Related GTPases (IRG) are a family of large GTPases that mediate innate immune responses. Irgm1 is particularly critical for immunity to bacteria…”
Get full text
Journal Article