Search Results - "Henry, Johnson"

Human Milk Oligosaccharides Increase Mucin Expression in Experimental Necrotizing Enterocolitis by Wu, Richard You, Li, Bo, Koike, Yuhki, Määttänen, Pekka, Miyake, Hiromu, Cadete, Marissa, Johnson‐Henry, Kathene C., Botts, Steven R., Lee, Carol, Abrahamsson, Thomas R., Landberg, Eva, Pierro, Agostino, Sherman, Philip M.

“…Scope Necrotizing enterocolitis (NEC) is a leading cause of morbidity and death in preterm infants, occurring more often in formula‐fed than breastfed infants…”
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Required Immunoproteasome Subunit Inhibition Profile for Anti-Inflammatory Efficacy and Clinical Candidate KZR-616 ((2S,3R)‑N‑((S)‑3-(Cyclopent-1-en-1-yl)-1-((R)‑2-methyloxiran-2-yl)-1-oxopropan-2-yl)-3-hydroxy-3-(4-methoxyphenyl)-2-((S)‑2-(2-morpholinoacetamido)­propanamido)­propenamide) by Johnson, Henry W. B, Lowe, Eric, Anderl, Janet L, Fan, Andrea, Muchamuel, Tony, Bowers, Simeon, Moebius, David C, Kirk, Christopher, McMinn, Dustin L

“…Selective immuno­proteasome inhibition is a promising approach for treating autoimmune disorders, but optimal proteolytic active site subunit inhibition…”
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Vitamin D Deficiency Promotes Epithelial Barrier Dysfunction and Intestinal Inflammation by Assa, Amit, Vong, Linda, Pinnell, Lee J., Avitzur, Naama, Johnson-Henry, Kathene C., Sherman, Philip M.

“…Background. Vitamin D, an important modulator of the immune system, has been shown to protect mucosal barrier homeostasis. This study investigates the effects…”
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Island narratives in the making of Japan: The Kojiki in geocultural context by Johnson, Henry

“…Shintō, the national religion of Japan, is grounded in the mythological narratives that are found in the 8th-Century chronicle, Kojiki 古事記 (712). Within this…”
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Lactobacillus rhamnosus Strain GG Prevents Enterohemorrhagic Escherichia coli O157:H7-Induced Changes in Epithelial Barrier Function by Johnson-Henry, K.C, Donato, K.A, Shen-Tu, G, Gordanpour, M, Sherman, P.M

“…Enterohemorrhagic Escherichia coli (EHEC) O157:H7 intimately attaches to intestinal epithelial monolayers and produces attaching and effacing (A/E) lesions. In…”
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GLP-1R Agonists Modulate Enteric Immune Responses Through the Intestinal Intraepithelial Lymphocyte GLP-1R by Yusta, Bernardo, Baggio, Laurie L, Koehler, Jacqueline, Holland, Dianne, Cao, Xiemin, Pinnell, Lee J, Johnson-Henry, Kathene C, Yeung, William, Surette, Michael G, Bang, K W Annie, Sherman, Philip M, Drucker, Daniel J

“…Obesity and diabetes are characterized by increased inflammation reflecting disordered control of innate immunity. We reveal a local intestinal intraepithelial…”
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Human Milk Oligosaccharides Protect against Necrotizing Enterocolitis by Activating Intestinal Cell Differentiation by Li, Bo, Wu, Richard You, Horne, Rachael G., Ahmed, Abdalla, Lee, Dorothy, Robinson, Shaiya C., Zhu, Haitao, Lee, Carol, Cadete, Marissa, Johnson‐Henry, Kathene C., Landberg, Eva, Alganabi, Mashriq, Abrahamsson, Thomas, Delgado‐Olguin, Paul, Pierro, Agostino, Sherman, Philip M.

“…Scope Necrotizing enterocolitis (NEC) is a devastating gastrointestinal emergency and currently the leading cause of mortality in preterm infants. Recent…”
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Co-inhibition of immunoproteasome subunits LMP2 and LMP7 enables prevention of transplant arteriosclerosis by Li, Jun, Hu, Shaobo, Johnson, Henry W B, Kirk, Christopher J, Xian, Peng, Song, Yanping, Li, Yuan, Liu, Nan, Groettrup, Marcus, Basler, Michael

“…Abstract Aims The loss of vascular wall cells in allotransplanted arteries is the initial event leading to transplant arteriosclerosis (TA) and ensuing loss of…”
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Structure–Function Relationships of Human Milk Oligosaccharides on the Intestinal Epithelial Transcriptome in Caco‐2 Cells and a Murine Model of Necrotizing Enterocolitis by Wu, Richard Y., Li, Bo, Horne, Rachael G., Ahmed, Abdalla, Lee, Dorothy, Robinson, Shaiya C., Zhu, Haitao, Cadete, Marissa, Alganabi, Mashriq, Filler, Rachel, Johnson‐Henry, Kathene C., Delgado‐Olguin, Paul, Pierro, Agostino, Sherman, Philip M.

“…Scope Necrotizing enterocolitis (NEC) is a devastating gastrointestinal emergency affecting preterm infants. Breastmilk protects against NEC, partly due to…”
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Plant‐ and Fish‐Derived n‐3 PUFAs Suppress Citrobacter Rodentium–Induced Colonic Inflammation by Määttänen, Pekka, Lurz, Eberhard, Botts, Steven R., Wu, Richard Y., Robinson, Shaiya C., Yeung, C. William, Colas, Romain, Li, Bo, Johnson‐Henry, Kathene C., Surette, Marc E., Dalli, Jesmond, Sherman, Philip M.

“…Scope Marine‐derived n‐3 PUFAs may ameliorate inflammation associated with inflammatory bowel diseases. Plant‐derived n‐3 PUFAs are thought to be inferior…”
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Timing and Source of Recharge to the Columbia River Basalt Groundwater System in Northeastern Oregon by Johnson, Henry M., Ely, Kate, Maher, Anna‐Turi

“…Recharge to and flow within the Columbia River Basalt Group (CRBG) groundwater flow system of northeastern Oregon were characterized using isotopic, gas, and…”
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Probiotics prevent bacterial translocation and improve intestinal barrier function in rats following chronic psychological stress by Zareie, M, Johnson-Henry, K, Jury, J, Yang, P-C, Ngan, B-Y, McKay, D M, Soderholm, J D, Perdue, M H, Sherman, P M

“…Background and aim: Chronic psychological stress, including water avoidance stress (WAS), induces intestinal mucosal barrier dysfunction and impairs mucosal…”
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Subsurface transport of orthophosphate in five agricultural watersheds, USA by Domagalski, Joseph L., Johnson, Henry M.

“…► Phosphorus transport in groundwater was assessed at five agricultural watersheds. ► Phosphorus subsurface movement was controlled by sorption onto iron…”
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Surface‐layer protein extracts from Lactobacillus helveticus inhibit enterohaemorrhagic Escherichia coli O157:H7 adhesion to epithelial cells by Johnson‐Henry, Kathene C., Hagen, Karen E., Gordonpour, Mahsa, Tompkins, Thomas A., Sherman, Philip M.

“…Summary Adherence of intestinal pathogens, including Escherichia coli O157:H7, to human intestinal epithelial cells is a key step in pathogenesis. Probiotic…”
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Springs as hydrologic refugia in a changing climate? A remote‐sensing approach by Cartwright, Jennifer, Johnson, Henry M.

“…Spring‐fed wetlands are ecologically important habitats in arid and semi‐arid regions. Springs have been suggested as possible hydrologic refugia from droughts…”
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Discovery of a Novel Class of Highly Potent, Selective, ATP-Competitive, and Orally Bioavailable Inhibitors of the Mammalian Target of Rapamycin (mTOR) by Takeuchi, Craig S, Kim, Byung Gyu, Blazey, Charles M, Ma, Sunghoon, Johnson, Henry W. B, Anand, Neel K, Arcalas, Arlyn, Baik, Tae Gon, Buhr, Chris A, Cannoy, Jonah, Epshteyn, Sergey, Joshi, Anagha, Lara, Katherine, Lee, Matthew S, Wang, Longcheng, Leahy, James W, Nuss, John M, Aay, Naing, Aoyama, Ron, Foster, Paul, Lee, Jae, Lehoux, Isabelle, Munagala, Narsimha, Plonowski, Arthur, Rajan, Sharmila, Woolfrey, John, Yamaguchi, Kyoko, Lamb, Peter, Miller, Nicole

“…A series of novel, highly potent, selective, and ATP-competitive mammalian target of rapamycin (mTOR) inhibitors based on a benzoxazepine scaffold have been…”
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Zetomipzomib (KZR-616) attenuates lupus in mice via modulation of innate and adaptive immune responses by Muchamuel, Tony, Fan, R Andrea, Anderl, Janet L, Bomba, Darrin J, Johnson, Henry W B, Lowe, Eric, Tuch, Brian B, McMinn, Dustin L, Millare, Beatriz, Kirk, Christopher J

“…Zetomipzomib (KZR-616) is a selective inhibitor of the immunoproteasome currently undergoing clinical investigation in autoimmune disorders. Here, we…”
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Vitamin D deficiency predisposes to adherent-invasive Escherichia coli-induced barrier dysfunction and experimental colonic injury by Assa, Amit, Vong, Linda, Pinnell, Lee J, Rautava, Jaana, Avitzur, Naama, Johnson-Henry, Kathene C, Sherman, Philip M

“…Adherent-invasive Escherichia coli (AIEC) colonization has been strongly implicated in the pathogenesis of Crohn's disease. Environmental triggers such as…”
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Short-chain fructo-oligosaccharide and inulin modulate inflammatory responses and microbial communities in Caco2-bbe cells and in a mouse model of intestinal injury by Johnson-Henry, Kathene C, Pinnell, Lee J, Waskow, Alexandra M, Irrazabal, Thergiory, Martin, Alberto, Hausner, Martina, Sherman, Philip M

“…Few studies have focused on the ability of prebiotics to prevent pathogen-induced cellular changes or alter the composition of the intestinal microbiota in…”
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Variations in the Composition of Human Milk Oligosaccharides Correlates with Effects on Both the Intestinal Epithelial Barrier and Host Inflammation: A Pilot Study by Wu, Richard Y, Botts, Steven R, Johnson-Henry, Kathene C, Landberg, Eva, Abrahamsson, Thomas R, Sherman, Philip M

“…Human milk oligosaccharides are complex, non-digestible carbohydrates that directly interact with intestinal epithelial cells to alter barrier function and…”
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