Search Results - "Henry, Jean‐Paul"

Selective Stimulation of Cardiac Lymphangiogenesis Reduces Myocardial Edema and Fibrosis Leading to Improved Cardiac Function Following Myocardial Infarction by Henri, Orianne, Pouehe, Chris, Houssari, Mahmoud, Galas, Ludovic, Nicol, Lionel, Edwards-Lévy, Florence, Henry, Jean-Paul, Dumesnil, Anais, Boukhalfa, Inès, Banquet, Sébastien, Schapman, Damien, Thuillez, Christian, Richard, Vincent, Mulder, Paul, Brakenhielm, Ebba

“…BACKGROUND—The lymphatic system regulates interstitial tissue fluid balance, and lymphatic malfunction causes edema. The heart has an extensive lymphatic…”
Get full text

Lymphatic and Immune Cell Cross-Talk Regulates Cardiac Recovery After Experimental Myocardial Infarction by Houssari, Mahmoud, Dumesnil, Anais, Tardif, Virginie, Kivelä, Riikka, Pizzinat, Nathalie, Boukhalfa, Ines, Godefroy, David, Schapman, Damien, Hemanthakumar, Karthik A., Bizou, Mathilde, Henry, Jean-Paul, Renet, Sylvanie, Riou, Gaetan, Rondeaux, Julie, Anouar, Youssef, Adriouch, Sahil, Fraineau, Sylvain, Alitalo, Kari, Richard, Vincent, Mulder, Paul, Brakenhielm, Ebba

“…OBJECTIVE:Lymphatics play an essential pathophysiological role in promoting fluid and immune cell tissue clearance. Conversely, immune cells may influence…”
Get full text

Myocardial Injury After Ischemia/Reperfusion Is Attenuated By Pharmacological Galectin-3 Inhibition by Ibarrola, Jaime, Matilla, Lara, Martínez-Martínez, Ernesto, Gueret, Alexandre, Fernández-Celis, Amaya, Henry, Jean-Paul, Nicol, Lionel, Jaisser, Frederic, Mulder, Paul, Ouvrard-Pascaud, Antoine, López-Andrés, Natalia

“…Although optimal therapy for myocardial infarction includes reperfusion to restore blood flow to the ischemic region, ischemia/reperfusion (IR) also initiates…”
Get full text

Vascular Smooth Muscle Mineralocorticoid Receptor Contributes to Coronary and Left Ventricular Dysfunction After Myocardial Infarction by Gueret, Alexandre, Harouki, Najah, Favre, Julie, Galmiche, Guillaume, Nicol, Lionel, Henry, Jean-Paul, Besnier, Marie, Thuillez, Christian, Richard, Vincent, Kolkhof, Peter, Mulder, Paul, Jaisser, Frédéric, Ouvrard-Pascaud, Antoine

“…Mineralocorticoid receptor (MR) antagonists slow down the progression of heart failure after myocardial infarction (MI), but the cell-specific role of MR in…”
Get full text

Enhanced angiogenesis and increased cardiac perfusion after myocardial infarction in protein tyrosine phosphatase 1B‐deficient mice by Besnier, Marie, Galaup, Ariane, Nicol, Lionel, Henry, Jean‐Paul, Coquerel, David, Gueret, Alexandre, Mulder, Paul, Brakenhielm, Ebba, Thuillez, Christian, Germain, Stéphane, Richard, Vincent, Ouvrard‐Pascaud, Antoine

“…The protein tyrosine phosphatase 1B (PTP1B) modulates tyrosine kinase receptors, among which is the vascular endothelial growth factor receptor type 2…”
Get full text

Ezh2 emerges as an epigenetic checkpoint regulator during monocyte differentiation limiting cardiac dysfunction post-MI by Rondeaux, Julie, Groussard, Déborah, Renet, Sylvanie, Tardif, Virginie, Dumesnil, Anaïs, Chu, Alphonse, Di Maria, Léa, Lemarcis, Théo, Valet, Manon, Henry, Jean-Paul, Badji, Zina, Vézier, Claire, Béziau-Gasnier, Delphine, Neele, Annette E., de Winther, Menno P. J., Guerrot, Dominique, Brand, Marjorie, Richard, Vincent, Durand, Eric, Brakenhielm, Ebba, Fraineau, Sylvain

“…Epigenetic regulation of histone H3K27 methylation has recently emerged as a key step during alternative immunoregulatory M2-like macrophage polarization;…”
Get full text

Role of M2-like macrophage recruitment during angiogenic growth factor therapy by Barbay, Virginie, Houssari, Mahmoud, Mekki, Malik, Banquet, Sebastien, Edwards-Lévy, Florence, Henry, Jean-Paul, Dumesnil, Anais, Adriouch, Sahil, Thuillez, Christian, Richard, Vincent, Brakenhielm, Ebba

“…Therapeutic angiogenesis has yet to fulfill its promise for the clinical treatment of ischemic diseases. Given the impact of macrophages during…”
Get full text

Toll-Like Receptors 2-Deficient Mice Are Protected Against Postischemic Coronary Endothelial Dysfunction by Favre, Julie, Musette, Philippe, Douin-Echinard, Victorine, Laude, Karine, Henry, Jean-Paul, Arnal, Jean-François, Thuillez, Christian, Richard, Vincent

“…OBJECTIVES—Toll-like receptors (TLR) 2 are expressed in cardiac and inflammatory cells, and regulate leukocyte function. Because leukocyte adhesion is a…”
Get full text

Arteriogenic Therapy by Intramyocardial Sustained Delivery of a Novel Growth Factor Combination Prevents Chronic Heart Failure by BANQUET, Sebastien, GOMEZ, Elodie, YIHAI CAO, THUILLEZ, Christian, MULDER, Paul, RICHARD, Vincent, BRAKENHIELM, Ebba, NICOL, Lionel, EDWARDS-LEVY, Florence, HENRY, Jean-Paul, CAO, Renhai, SCHAPMAN, Damien, DAUTREAUX, Brigitte, LALLEMAND, Francoise, BAUER, Fabrice

“…Therapeutic angiogenesis is a promising approach for the treatment of cardiovascular diseases, including myocardial infarction and chronic heart failure. We…”
Get full text

The IL-1β Antibody Gevokizumab Limits Cardiac Remodeling and Coronary Dysfunction in Rats With Heart Failure by Harouki, Najah, BS, Nicol, Lionel, PhD, Remy-Jouet, Isabelle, PhD, Henry, Jean-Paul, BS, Dumesnil, Anais, BS, Lejeune, Annie, BS, Renet, Sylvanie, BS, Golding, Francesca, BS, Djerada, Zoubir, PhD, Wecker, Didier, PhD, Bolduc, Virginie, PhD, Bouly, Muriel, PhD, Roussel, Jerome, PhD, Richard, Vincent, PhD, Mulder, Paul, PhD

“…Visual Abstract…”
Get full text

Mineralocorticoid receptor blockade with finerenone improves heart function and exercise capacity in ovariectomized mice by Pieronne‐Deperrois, Marie, Guéret, Alexandre, Djerada, Zoubir, Crochemore, Clément, Harouki, Najah, Henry, Jean‐Paul, Dumesnil, Anaïs, Larchevêque, Marine, Rego, Jean‐Claude, Rego, Jean‐Luc, Nicol, Lionel, Richard, Vincent, Jaisser, Frédéric, Kolkhof, Peter, Mulder, Paul, Monteil, Christelle, Ouvrard‐Pascaud, Antoine

“…Aims In post‐menopausal women, incidence of heart failure with preserved ejection fraction is higher than in men. Hormonal replacement therapies did not…”
Get full text

Reduction of heart failure by pharmacological inhibition or gene deletion of protein tyrosine phosphatase 1B by Gomez, Elodie, Vercauteren, Magali, Kurtz, Baptiste, Ouvrard-Pascaud, Antoine, Mulder, Paul, Henry, Jean-Paul, Besnier, Marie, Waget, Aurélie, Hooft Van Huijsduijnen, Rob, Tremblay, Michel L, Burcelin, Remy, Thuillez, Christian, Richard, Vincent

“…Abstract Protein tyrosine phosphatase 1B (PTP1B) regulates tyrosine kinase receptor-mediated responses, and especially negatively influences insulin…”
Get full text

Selective Vascular Endothelial Protection Reduces Cardiac Dysfunction in Chronic Heart Failure by Maupoint, Julie, Besnier, Marie, Gomez, Elodie, Bouhzam, Najime, Henry, Jean-Paul, Boyer, Olivier, Nicol, Lionel, Mulder, Paul, Martinet, Jérémie, Richard, Vincent

“…Chronic heart failure (CHF) induces endothelial dysfunction in part because of decreased nitric oxide (NO(·)) production, but the direct link between…”
Get full text

Heart Rate Reduction Induced by the If Current Inhibitor Ivabradine Improves Diastolic Function and Attenuates Cardiac Tissue Hypoxia by Fang, Yuehua, Debunne, Manuelle, Vercauteren, Magali, Brakenhielm, Ebba, Richard, Vincent, Lallemand, Francoise, Henry, Jean-Paul, Mulder, Paul, Thuillez, Christian

“…AIMSEnhanced heart rate (HR) is a compensatory mechanism in chronic heart failure (CHF), preserving cardiac output, but at the cost of increased left…”
Get full text

Transient heart rate reduction improves acute decompensated heart failure‐induced left ventricular and coronary dysfunction by Peschanski, Nicolas, Harouki, Najah, Soulie, Matthieu, Lachaux, Marianne, Nicol, Lionel, Remy‐Jouet, Isabelle, Henry, Jean‐Paul, Dumesnil, Anais, Renet, Sylvanie, Fougerousse, Françoise, Brakenhielm, Ebba, Ouvrard‐Pascaud, Antoine, Thuillez, Christian, Richard, Vincent, Roussel, Jérôme, Mulder, Paul

“…Aims Acute decompensated heart failure (ADHF), a live‐threatening complication of heart failure (HF), associates a further decrease of the already by…”
Get full text

Immunological tolerance to muscle autoantigens involves peripheral deletion of autoreactive CD8+ T cells by Franck, Emilie, Bonneau, Carole, Jean, Laetitia, Henry, Jean-Paul, Lacoume, Yann, Salvetti, Anna, Boyer, Olivier, Adriouch, Sahil

“…Muscle potentially represents the most abundant source of autoantigens of the body and can be targeted by a variety of severe autoimmune diseases. Yet, the…”
Get full text

Improvement of peripheral endothelial dysfunction by protein tyrosine phosphatase inhibitors in heart failure by VERCAUTEREN, Magali, REMY, Elise, RICHARD, Vincent, DEVAUX, Corinne, DAUTREAUX, Brigitte, HENRY, Jean-Paul, BAUER, Fabrice, MULDER, Paul, VAN HUIJSDUIJNEN, Rob Hooft, BOMBRUN, Agnès, THUILLEZ, Christian

“…Chronic heart failure (CHF) induces endothelial dysfunction characterized by a decrease in nitric oxide (NO) production in response to flow (flow-mediated…”
Get full text

Transient reduction in myocardial free oxygen radical levels is involved in the improved cardiac function and structure after long-term allopurinol treatment initiated in established chronic heart failure by Mellin, Virginie, Isabelle, Marc, Oudot, Alexandra, Vergely-Vandriesse, Catherine, Monteil, Christelle, Di Meglio, Benoit, Henry, Jean Paul, Dautreaux, Brigitte, Rochette, Luc, Thuillez, Christian, Mulder, Paul

“…Aims Oxidative stress, i.e. imbalance between reactive oxygen species (ROS) and antioxidant defences, contributes to the progression of chronic heart failure…”
Get full text

Tissue Doppler imaging differentiates physiological from pathological pressure-overload left ventricular hypertrophy in rats by DERUMEAUX, Geneviève, MULDER, Paul, RICHARD, Vincent, CHAGRAOUI, Abdeslam, NAFEH, Catherine, BAUER, Fabrice, HENRY, Jean-Paul, THUILLEZ, Christian

“…The myocardial velocity gradient (MVG) is a recent index of regional myocardial function derived from endocardial and epicardial velocities obtained by tissue…”
Get full text

NADPH oxidase inhibition prevents cocaine-induced up-regulation of xanthine oxidoreductase and cardiac dysfunction by Isabelle, Marc, Vergeade, Aurélia, Moritz, Fabienne, Dautréaux, Brigitte, Henry, Jean-Paul, Lallemand, Françoise, Richard, Vincent, Mulder, Paul, Thuillez, Christian, Monteil, Christelle

“…Abstract Oxidative stress is involved in the pathogenesis of cocaine-induced cardiomyopathy. In the present study, we aimed to determine the enzymatic sources…”
Get full text