Search Results - "Henry, Christelle"
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Efficient Screening of Target-Specific Selected Compounds in Mixtures by 19 F NMR Binding Assay with Predicted 19 F NMR Chemical Shifts
Published in ChemMedChem (05-07-2022)“…Ligand-based F NMR screening is a highly effective and well-established hit-finding approach. The high sensitivity to protein binding makes it particularly…”
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Efficient Screening of Target‐Specific Selected Compounds in Mixtures by 19F NMR Binding Assay with Predicted 19F NMR Chemical Shifts
Published in ChemMedChem (05-07-2022)“…Ligand‐based 19F NMR screening is a highly effective and well‐established hit‐finding approach. The high sensitivity to protein binding makes it particularly…”
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Low-dose CT with automatic tube current modulation, adaptive statistical iterative reconstruction, and low tube voltage for the diagnosis of renal colic: impact of body mass index
Published in American journal of roentgenology (1976) (01-03-2014)“…The objective of our study was to evaluate the impact of body mass index (BMI) on dose, diagnostic performance, and image quality of a low-dose CT examination…”
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Inside Cover: Comprehensive and High‐Throughput Exploration of Chemical Space Using Broadband 19F NMR‐Based Screening (Angew. Chem. Int. Ed. 35/2020)
Published in Angewandte Chemie International Edition (24-08-2020)“…19F NMR‐based fragment screening is an effective approach in pharmaceutical research to explore the chemical space for specific target–ligand interactions. In…”
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Cerebrospinal Fluid Aβ42/Aβ40 as a Means to Limiting Tube- and Storage-Dependent Pre-Analytical Variability in Clinical Setting
Published in Journal of Alzheimer's disease (2017)“…Alzheimer's disease (AD) cerebrospinal fluid (CSF) biomarkers have recently been included in the criteria for AD diagnosis. Unfortunately, their wider use in…”
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Comprehensive and High-Throughput Exploration of Chemical Space Using Broadband 19 F NMR-Based Screening
Published in Angewandte Chemie International Edition (24-08-2020)“…Fragment-based lead discovery has become a fundamental approach to identify ligands that efficiently interact with disease-relevant targets. Among the numerous…”
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Comprehensive and High‐Throughput Exploration of Chemical Space Using Broadband 19F NMR‐Based Screening
Published in Angewandte Chemie International Edition (24-08-2020)“…Fragment‐based lead discovery has become a fundamental approach to identify ligands that efficiently interact with disease‐relevant targets. Among the numerous…”
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9
Gastric Wall Fatty Infiltration in Patients Without Overt Gastrointestinal Disease
Published in American journal of roentgenology (1976) (01-04-2016)“…The purpose of this study was to evaluate the frequency of gastric wall fatty infiltration in patients without overt gastrointestinal disease. A retrospective…”
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Innentitelbild: Comprehensive and High‐Throughput Exploration of Chemical Space Using Broadband 19 F NMR‐Based Screening (Angew. Chem. 35/2020)
Published in Angewandte Chemie (24-08-2020)Get full text
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Comprehensive and High‐Throughput Exploration of Chemical Space Using Broadband 19 F NMR‐Based Screening
Published in Angewandte Chemie (24-08-2020)“…Abstract Fragment‐based lead discovery has become a fundamental approach to identify ligands that efficiently interact with disease‐relevant targets. Among the…”
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Innentitelbild: Comprehensive and High‐Throughput Exploration of Chemical Space Using Broadband 19F NMR‐Based Screening (Angew. Chem. 35/2020)
Published in Angewandte Chemie (24-08-2020)“…19F‐NMR‐basiertes Fragmentscreening ist ein effektiver Ansatz in der pharmazeutischen Forschung zur Untersuchung des chemischen Substanzraums für spezifische…”
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Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding
Published in ChemMedChem (01-11-2015)“…Farnesyl pyrophosphate synthase (FPPS) is an established target for the treatment of bone diseases, but also shows promise as an anticancer and anti‐infective…”
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Characterization of 6-deoxy-6-iodo-D-glucose: A potential new tool to assess glucose transport
Published in Nuclear medicine and biology (1997)“…6-deoxy-6-iodo- d-glucose (6-DIG) was rapidly taken up by adipocytes. Insulin increased 6-DIG transport in adipocytes isolated from both rats and mice. This…”
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Comprehensive and High‐Throughput Exploration of Chemical Space Using Broadband 19F NMR‐Based Screening
Published in Angewandte Chemie (24-08-2020)“…Fragment‐based lead discovery has become a fundamental approach to identify ligands that efficiently interact with disease‐relevant targets. Among the numerous…”
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Time efficient detection of protein-ligand interactions with the polarization optimized PO-WaterLOGSY NMR experiment
Published in Journal of biomolecular NMR (01-04-2009)“…The identification of compounds that bind to a protein of interest is of central importance in contemporary drug research. For screening of compound libraries,…”
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Innentitelbild: Comprehensive and High‐Throughput Exploration of Chemical Space Using Broadband 19F NMR‐Based Screening
Published in Angewandte Chemie (01-08-2020)“…19F‐NMR‐basiertes Fragmentscreening ist ein effektiver Ansatz in der pharmazeutischen Forschung zur Untersuchung des chemischen Substanzraums für spezifische…”
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18
Effects of pedunculopontine nucleus area stimulation on gait disorders in Parkinson's disease
Published in Brain (London, England : 1878) (01-01-2010)“…Gait disturbances are frequent and disabling in advanced Parkinson's disease. These symptoms respond poorly to usual medical and surgical treatments but were…”
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Design, characterization and processing of cellulose-S-acetyl: a precursor to an electroactive cellulose
Published in Macromolecular chemistry and physics (01-12-1998)“…The synthesis and characterization of Cell‐SAc 3, a cellulose isopentyl (IP) ether with additional pendant S‐acetyl (SAc) moieties (degree of substitution DSIP…”
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[ 123I]-6-deoxy-6-iodo- d-glucose (6DIG): A potential tracer of glucose transport
Published in Nuclear medicine and biology (01-08-1997)“…A glucose analogue labelled with iodine-123 in position 6 has been synthesized: [ 123I]-6-deoxy-6-iodo- d-glucose (6DIG). The aim of this study was to examine…”
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