Search Results - "Henrotin, Y.E"

Mechanical loading highly increases IL-6 production and decreases OPG expression by osteoblasts by Sanchez, C., Ph.D, Gabay, O., Ph.D, Salvat, C., B.Sc, Henrotin, Y.E., Ph.D, Berenbaum, F., M.D., Ph.D

“…Summary Objectives In osteoarthritis (OA), mechanical factors play a key role, not only in cartilage degradation, but also in subchondral bone sclerosis. The…”
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The role of reactive oxygen species in homeostasis and degradation of cartilage by Henrotin, Y.E, Bruckner, P, Pujol, J.-P.L

“…Objectives: The metabolism of cells in articular joint tissues in normal and pathological conditions is subject to a complex environmental control. In addition…”
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Subchondral bone osteoblasts induce phenotypic changes in human osteoarthritic chondrocytes by Sanchez, C., Deberg, M.A., Piccardi, N., Msika, P., Reginster, J.-Y.L., Henrotin, Y.E.

“…To determine the influence of osteoarthritic (OA) phenotype of subchondral osteoblasts on the phenotype of human chondrocytes. Human chondrocytes were isolated…”
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Association of urinary biomarker COLL2-1NO2 with incident clinical and radiographic knee OA in overweight and obese women by Landsmeer, M.L.A, Runhaar, J, Henrotin, Y.E, Middelkoop van, M, Oei, E.H.G, Vroegindeweij, D, Reijman, M, van Osch, G.J.V.M, Koes, B.W, Bindels, P.J.E, Bierma-Zeinstra, S.M.A

“…Summary Objective To investigate the association between urinary biomarker Coll2-1NO2 (uColl2-1NO2 ) and incident knee OA after 2.5 years follow-up in…”
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Coll2-1NO2: a biomarker for early knee osteoarthritis? by Landsmeer, M.L, Runhaar, J, Henrotin, Y.E, van Middelkoop, M, Oei, E.H, Vroegindeweij, D, van der Plas, P, Reijman, M, van Osch, G, Bindels, P, Bierma-Zeinstra, S.M

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One-year increase of Coll 2-1, a new marker of type II collagen degradation, in urine is highly predictive of radiological OA progression by Deberg, M.A., Labasse, A.H., Collette, J., Seidel, L., Reginster, J.-Y., Henrotin, Y.E.

“…To analyse the relationship between the levels of urinary biochemical markers of type II collagen degradation and the clinical and radiological severity and…”
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483 MATRIX METALLOPROTEINASE-3 IS A HIGLY MECHANO-SENSITIVE GENE IN HUMAN SUBCHONDRAL OSTEOBLASTS by Sanchez, C, Pesesse, L, Delcour, J.-P, Msika, P, Baudouin, C, Henrotin, Y.E

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159 COMPRESSION INDUCES THE EXPRESSION OF A SCLEROTIC PHENOTYPE IN HUMAN SUBCHONDRAL OSTEOBLASTS by Sanchez, C, Gabay, O, Pesesse, L, Msika, P, Baudouin, C, Henrotin, Y.E

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Osteoblasts from the sclerotic subchondral bone downregulate aggrecan but upregulate metalloproteinases expression by chondrocytes. This effect is mimicked by interleukin-6, -1β and oncostatin M pre-treated non-sclerotic osteoblasts by Sanchez, C., Deberg, M.A., Piccardi, N., Msika, P., Reginster, J.-Y.L., Henrotin, Y.E.

“…To determine the effects of osteoarthritic (OA) subchondral osteoblasts on the metabolism of human OA chondrocytes in alginate beads. Human chondrocytes were…”
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Association of urinary biomarker COLL2-1NO 2 with incident clinical and radiographic knee OA in overweight and obese women by Landsmeer, M.L.A., Runhaar, J., Henrotin, Y.E., Middelkoop van, M., Oei, E.H.G., Vroegindeweij, D., Reijman, M., van Osch, G.J.V.M., Koes, B.W., Bindels, P.J.E., Bierma-Zeinstra, S.M.A.

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Correlation between radiographic severity of knee osteoarthritis and future disease progression. Results from a 3-year prospective, placebo-controlled study evaluating the effect of glucosamine sulfate by Bruyere, O., Honore, A., Ethgen, O., Rovati, L.C., Giacovelli, G., Henrotin, Y.E., Seidel, L., Reginster, J.-Y.L.

“…Objective To investigate the relationship between baseline radiographic severity of knee osteoarthritis (OA) and the importance of long-term joint space…”
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Regulation by reactive oxygen species of interleukin-1β, nitric oxide and prostaglandin E2 production by human chondrocytes by Mathy-Hartert, M., Deby-Dupont, G.P., Reginster, J.-Y.L., Ayache, N., Pujol, J.-P., Henrotin, Y.E.

“…Objectives To determine the effects of two drugs, N-monomethyl-L-arginine (L-NMMA) and N-acetylcysteine (NAC), on interleukin-1β (IL-1β), nitric oxide (NO) and…”
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Modulation of human chondrocyte metabolism by recombinant human interferon by Henrotin, Y.E, Zheng, S.X, Labasse, A.H, Deby, G.P, Crielaard, J-M.R, Reginster, J-Y.L

“…Objectives Interferon gamma (IFNγ) is found to be elevated in the synovial fluid of patients with rheumatoid arthritis and osteoarthritis, suggesting its…”
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In vitro study of the antioxidant properties of nimesulide and 4-OH nimesulide: effects on HRP- and luminol-dependent chemiluminescence produced by human chondrocytes by Zheng, S.X, Mouithys-Mickalad, A, Deby-Dupont, G.P, Deby, C.M.-T, Maroulis, A.P, Labasse, A.H, Lamy, M.L, Crielaard, J.-M.R, Reginster, J.-Y.L, Henrotin, Y.E

“…Objectives Reactive oxygen species (ROS) are now recognized to play an important role in the pathogenesis of rheumatic diseases and constitute an interesting…”
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