Search Results - "Henriques, Maria das Graças M. O."

Synthesis and antimycobacterial activity of N′-[( E)-(monosubstituted-benzylidene)]-2-pyrazinecarbohydrazide derivatives by Vergara, Fátima M.F., Lima, Camilo H. da S., Henriques, Maria das Graças M. de O., Candéa, André L.P., Lourenço, Maria C.S., Ferreira, Marcelle de L., Kaiser, Carlos R., de Souza, Marcus V.N.

“…The present article describes a series of twenty-six N′-[( E)-(monosubstituted-benzylidene)]-2-pyrazinecarbohydrazide ( 4– 29), which were synthesized and…”
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Anti-Inflammatory Activity and Chemical Analysis of Different Fractions from Solidago chilensis Inflorescence by de Brito, Thais Morais, Amendoeira, Fabio Coelho, de Oliveira, Temistocles Barroso, Doro, Laís Higino, Garcia, Esdras Barbosa, da Silva, Naína Monsores Felix, da Silva Chaves, Amanda, Muylaert, Flavia Fontenelle, Pádua, Tatiana Almeida, Rosas, Elaine Cruz, Henriques, Maria das Graças M. O., da Silva Frutuoso, Valber, Valverde, Simone Sacramento, Ferraris, Fausto Klabund

“…Solidago chilensis Meyen (Compositae) is a species native to South America (Brazil) popularly known as arnica. In Brazilian popular medicine, inflorescences…”
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Effects of endothelin ETA receptor antagonism on granulocyte and lymphocyte accumulation in LPS-induced inflammation by Sampaio, André L. F., Rae, Giles A., Henriques, Maria das Graças M. O.

“…Endothelin peptides play active roles in different aspects of inflammation. This study investigates the contribution of endogenous endothelins to…”
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Gedunin, a natural tetranortriterpenoid, modulates T lymphocyte responses and ameliorates allergic inflammation by Ferraris, Fausto K., Moret, Katelim Hottz, Figueiredo, Alexandre Bezerra Conde, Penido, Carmen, Henriques, Maria das Graças M.O.

“…T lymphocytes are critical cells involved in allergy. Here, we report that the natural tetranortriterpenoid gedunin impaired allergic responses primarily by…”
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Modulation of T lymphocyte and eosinophil functions in vitro by natural tetranortriterpenoids isolated from Carapa guianensis Aublet by Ferraris, Fausto K., Rodrigues, Rodrigo, da Silva, Vagner P., Figueiredo, Raquel, Penido, Carmen, Henriques, Maria das Graças M.O.

“…We have previously described the anti-allergic activities of a pooled fraction of tetranortriterpenoids (TNTPs) containing 6α-acetoxygedunin,…”
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Exposure to the UV Filter Octyl Methoxy Cinnamate in the Postnatal Period Induces Thyroid Dysregulation and Perturbs the Immune System of Mice by Ferraris, Fausto Klabund, Garcia, Esdras Barbosa, Chaves, Amanda da Silva, de Brito, Thais Morais, Doro, Laís Higino, Félix da Silva, Naína Monsores, Alves, Amanda Soares, Pádua, Tatiana Almeida, Henriques, Maria das Graças M O, Cardoso Machado, Tiago Savignon, Amendoeira, Fabio Coelho

“…Evidence demonstrates the bidirectional communication and regulation between the neuroendocrine and immune systems. Thyroid hormones play key roles in nervous…”
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Modulation of Inflammatory Processes by Leaves Extract from Clusia nemorosa Both In Vitro and In Vivo Animal Models by Farias, José Alex C., Ferro, Jamylle Nunes S., Silva, Juliane P., Agra, Isabela Karine R., Oliveira, Fernando M., Candea, André Luiz P., Conte, Fernando P., Ferraris, Fausto K., Henriques, Maria das Graças M. O., Conserva, Lucia M., Barreto, Emiliano

“…The present study was carried out to investigate the anti-inflammatory effect of the hexane extract of the leaves from Clusia nemorosa G. Mey, called HECn,…”
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Endothelins modulate inflammatory reaction in zymosan-induced arthritis: participation of LTB4, TNF-α, and CXCL-1 by Conte, Fernando de Paiva, Barja-Fidalgo, Christina, Verri, Jr, Waldiceu A, Cunha, Fernando Queiroz, Rae, Giles A, Penido, Carmen, Henriques, Maria das Graças M O

“…Endothelins (ETs) are involved in inflammatory events, including pain, fever, edema, and cell migration. ET‐1 levels are increased in plasma and synovial…”
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Artesunate Exerts a Direct Effect on Endothelial Cell Activation and NF-κB Translocation in a Mechanism Independent of Plasmodium Killing by Souza, Mariana C., Paixão, Flávio Henrique Marcolino, Ferraris, Fausto K., Ribeiro, Isabela, Henriques, Maria das Graças M. O.

“…Artemisinin and its derivates are an important class of antimalarial drug and are described to possess immunomodulatory activities. Few studies have addressed…”
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Synthesis and anti-mycobacterial activity of ( E)- N′-(monosubstituted-benzylidene)isonicotinohydrazide derivatives by Lourenço, Maria Cristina da Silva, Ferreira, Marcelle de Lima, de Souza, Marcus Vinícius Nora, Peralta, Mônica Amado, Vasconcelos, Thatyana Rocha Alves, Henriques, Maria das Graças M.O.

“…A series of 22 ( E)- N′-(monosubstituted-benzylidene)isonicotinohydrazide derivatives have been synthesized and evaluated for their in vitro antibacterial…”
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Metabonomics reveals drastic changes in anti-inflammatory/pro-resolving polyunsaturated fatty acids-derived lipid mediators in leprosy disease by Amaral, Julio J, Antunes, Luis Caetano M, de Macedo, Cristiana S, Mattos, Katherine A, Han, Jun, Pan, Jingxi, Candéa, André L P, Henriques, Maria das Graças M O, Ribeiro-Alves, Marcelo, Borchers, Christoph H, Sarno, Euzenir N, Bozza, Patrícia T, Finlay, B Brett, Pessolani, Maria Cristina V

“…Despite considerable efforts over the last decades, our understanding of leprosy pathogenesis remains limited. The complex interplay between pathogens and…”
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Synthesis and antitubercular activity of heteroaromatic isonicotinoyl and 7-chloro-4-quinolinyl hydrazone derivatives by Ferreira, Marcelle de L, Gonçalves, Raoni S B, Cardoso, Laura N de F, Kaiser, Carlos R, Candea, Andre L P, Henriques, Maria das Graças M de O, Lourenço, Maria C S, Bezerra, Flavio A F M, de Souza, Marcus V N

“…Two series of N'-(E)-heteroaromatic-isonicotinohydrazide derivatives (3a-f and 4a-b) and 1-(7-chloroquinolin-4-yl)-2-[(heteroaromatic)methylene]hydrazone…”
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Mefloquine–oxazolidine derivatives, derived from mefloquine and arenecarbaldehydes: In vitro activity including against the multidrug-resistant tuberculosis strain T113 by Gonçalves, Raoni S.B., Kaiser, Carlos R., Lourenço, Maria C.S., Bezerra, Flavio A.F.M., de Souza, Marcus V.N., Wardell, James L., Wardell, Solange M.S.V., Henriques, Maria das Graças M.de O., Costa, Thadeu

“…Ten new mefloquine–oxazolidine derivatives, 4-[(1S,8aR)-3-(aryl)hexahydro[1,3]oxazolo[3,4-a]pyridin-1-yl]-2,8-bis(trifluoromethyl)quinoline (1:…”
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Targeting endothelin ETA and ETB receptors inhibits antigen-induced neutrophil migration and mechanical hypernociception in mice by Verri Jr, Waldiceu A., Cunha, Thiago M., Magro, Danilo A., Guerrero, Ana T. G., Vieira, Silvio M., Carregaro, Vanessa, Souza, Guilherme R., Henriques, Maria das Graças M. O., Ferreira, Sérgio H., Cunha, Fernando Q.

“…Endothelin may contribute to the development of inflammatory events such as leukocyte recruitment and nociception. Herein, we investigated whether…”
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Synthesis and antitubercular activity of 7-chloro-4-quinolinylhydrazones derivatives by Candéa, André L.P., Ferreira, Marcelle de L., Pais, Karla C., Cardoso, Laura N.de F., Kaiser, Carlos R., Henriques, Maria das Graças M.de O., Lourenço, Maria C.S., Bezerra, Flávio A.F.M., de Souza, Marcus V.N.

“…A series of twenty-one quinoline derivatives have been synthesized and evaluated against Mycobacterium tuberculosis. Three compounds exhibited a significant…”
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Mitochondrial localization of non-histone protein HMGB1 during human endothelial cell– Toxoplasma gondii infection by Stumbo, Ana Carolina, Cortez, Erika, Rodrigues, Carlos Alberto, Henriques, Maria das Graças M.O., Porto, Luís Cristóvão, Barbosa, Helene S., Carvalho, Laís

“…Toxoplasma gondii is an obligate intracellular pathogen, replicating only within a specialized membrane-bounded cytoplasmic vacuole, the parasitophorous…”
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Antitubercular Activity of New Coumarins by Cardoso, Silvia H., Barreto, Milena B., Lourenço, Maria C. S., Henriques, Maria das Graças M. de O., Candéa, André L. P., Kaiser, Carlos R., de Souza, Marcus V. N.

“…The present article describes a series of 21 N ′‐benzylidene‐2‐oxo‐2H‐chromene‐3‐carbohydrazides 4a–4v, which were synthesized and evaluated for their cell…”
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Activation of human T lymphocytes via integrin signaling induced by RGD-disintegrins by Neto, Edward Helal, Coelho, Ana Lúcia J., Sampaio, André Luiz Franco, Henriques, Maria das Graças M.O., Marcinkiewicz, Cezary, De Freitas, Marta S., Barja-Fidalgo, Christina

“…Adhesive interactions play important roles in coordinating T cell migration and activation, which are mediated by binding of integrins to RGD motif found on…”
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Frutalin, a galactose-binding lectin, induces chemotaxis and rearrangement of actin cytoskeleton in human neutrophils: Involvement of tyrosine kinase and phosphoinositide 3-kinase by Brando-Lima, Aline C., Saldanha-Gama, Roberta F., Henriques, Maria das Graças M.O., Monteiro-Moreira, Ana C.O., Moreira, Renato A., Barja-Fidalgo, Christina

“…Several lectin-like molecules have been shown as potent activators of leukocytes. Galactose-binding lectins are of special interest since they could interact…”
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Involvement of phosphatidylinositol-3 kinase–Akt and nuclear factor kappa-B pathways in the effect of frutalin on human lymphocyte by Brando-Lima, Aline C., Saldanha-Gama, Roberta F., Pereira, Cristiane Ribeiro, Villela, Christina Gaspar, Sampaio, André Luiz Franco, Monteiro-Moreira, Ana C.O., Henriques, Maria das Graças M.O., Moreira, Renato A., Barja-Fidalgo, Christina

“…The mechanisms involved in the mitogenic effect of lectins are not fully understood and are thought to involve a cascade of intracellular signals related to T…”
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