Search Results - "Henriques, Joao Antonio Pegas"

Cytotoxicity and genotoxicity induced by coal and coal fly ash particles samples in V79 cells by León-Mejía, Grethel, Silva, Luis F. O., Civeira, Matheus S., Oliveira, Marcos L. S., Machado, Miriana, Villela, Izabel Vianna, Hartmann, Andreas, Premoli, Suziane, Corrêa, Dione Silva, Da Silva, Juliana, Henriques, João Antônio Pêgas

“…Exposure to coal and coal ashes can cause harmful effects in in vitro and in vivo systems, mainly by the induction of oxidative damage. The aim of this work…”
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Brazilian Red Propolis Induces Apoptosis-Like Cell Death and Decreases Migration Potential in Bladder Cancer Cells by Savegnago, Lucielli, Moura, Sidnei, Padilha, Francine F., Collares, Tiago, Pêgas Henriques, João Antonio, Seixas, Fabiana K., Dellagostin, Odir A., Borsuk, Sibele, Martins Rodrigues, Fernanda, Campos, Vinicius Farias, Schultze, Eduarda, Thurow, Helena, Moura de Leon, Priscila Marques, Begnini, Karine Rech, Roesch-Ely, Mariana

“…Natural products continue to be an invaluable resource of anticancer drug discovery in recent years. Propolis is known for its biological activities such as…”
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Natural Rubber Films Incorporated with Red Propolis and Silver Nanoparticles Aimed for Occlusive Dressing Application by Garcia, Charlene Silvestrin Celi, Maddalozzo, Ana Elisa Dotta, Garcia, Paulo Miguel Celi, Fontoura, Cristian Padilha, Rodrigues, Melissa Machado, Giovanela, Marcelo, Henriques, João Antonio Pêgas, Aguzzoli, Cesar, Silva Crespo, Janaina da, Roesch-Ely, Mariana

“…Abstract In this work, NRL films were enriched with red propolis and silver nanoparticles with the aim of obtaining dressings with bactericide properties. To…”
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Nek1 silencing slows down DNA repair and blocks DNA damage-induced cell cycle arrest by Pelegrini, Alessandra Luíza, Moura, Dinara Jaqueline, Brenner, Bethânia Luise, Ledur, Pitia Flores, Maques, Gabriela Porto, Henriques, João Antônio Pegas, Saffi, Jenifer, Lenz, Guido

“…Never in mitosis A (NIMA)-related kinases (Nek) are evolutionarily conserved proteins structurally related to the Aspergillus nidulans mitotic regulator NIMA…”
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Iron intake, red cell indicators of iron status, and DNA damage in young subjects by Prá, Daniel, Ph.D, Bortoluzzi, Angelica, B.Nutr, Müller, Luiza Louzada, B.Nutr, Hermes, Liziane, B.Nutr, Horta, Jorge André, Ph.D, Maluf, Sharbel Weidner, Ph.D, Henriques, João Antonio Pêgas, Ph.D, Fenech, Michael, Ph.D, Franke, Silvia Isabel Rech, Ph.D

“…Abstract Objective This study evaluated the association between primary DNA damage and chromosomal damage with iron intake and red blood cell parameters of…”
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Chemical Composition and Biological Activity of Extracts Obtained by Supercritical Extraction and Ethanolic Extraction of Brown, Green and Red Propolis Derived from Different Geographic Regions in Brazil by Machado, Bruna Aparecida Souza, Silva, Rejane Pina Dantas, Barreto, Gabriele de Abreu, Costa, Samantha Serra, Silva, Danielle Figuerêdo da, Brandão, Hugo Neves, Rocha, José Luiz Carneiro da, Dellagostin, Odir Antônio, Henriques, João Antônio Pegas, Umsza-Guez, Marcelo Andres, Padilha, Francine Ferreira

“…The variations in the chemical composition, and consequently, on the biological activity of the propolis, are associated with its type and geographic origin…”
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Chemical characterization, antioxidant and cytotoxic activities of Brazilian red propolis by da Silva Frozza, Caroline Olivieri, Garcia, Charlene Silvestrin Celi, Gambato, Gabriela, de Souza, Marcia Denize Oliveira, Salvador, Mirian, Moura, Sidnei, Padilha, Francine Ferreira, Seixas, Fabiana Kömmling, Collares, Tiago, Borsuk, Sibele, Dellagostin, Odir Antonio, Henriques, João Antonio Pêgas, Roesch-Ely, Mariana

“…► First report using red propolis from Sergipe, a region on northeast of Brazil. ► Red propolis from Sergipe was analyzed by ESI-MS and ESI-MS/MS for the first…”
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5-Fluorouracil and its active metabolite FdUMP cause DNA damage in human SW620 colon adenocarcinoma cell line by Matuo, Renata, Sousa, Fabrício Garmus, Escargueil, Alexandre E., Grivicich, Ivana, Garcia-Santos, Daniel, Chies, José Artur Bogo, Saffi, Jenifer, Larsen, Annette K., Henriques, João Antonio Pêgas

“…5‐Fluorouracil (5‐FU) is an antineoplasic drug widely used to treat cancer. Its cytotoxic effect has been principally ascribed to the misincorporation of…”
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Genetic damage in coal miners evaluated by buccal micronucleus cytome assay by León-Mejía, Grethel, Quintana, Milton, Debastiani, Rafaela, Dias, Johnny, Espitia-Pérez, Lyda, Hartmann, Andreas, Henriques, João Antônio Pêgas, Da Silva, Juliana

“…During coal mining activities, large quantities of coal dust, ashes, polycyclic aromatic hydrocarbons and metals are released into the environment. This…”
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SnCl₂-induced DNA damage and repair inhibition of MMS-caused lesions in V79 Chinese hamster fibroblasts by Viau, C. M, Guecheva, Temenouga N, Sousa, F. G, Pungartnik, C, Brendel, M, Saffi, J, Henriques, João Antonio Pêgas

“…In order to clarify the molecular mechanisms of Sn²⁺ genotoxicity, we evaluated the induction of strand breaks, formamidopyrimidine DNA glycosylase (Fpg) and…”
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Origanum majorana Essential Oil Lacks Mutagenic Activity in the Salmonella/Microsome and Micronucleus Assays by Mello, João Roberto Braga de, Pêgas Henriques, João Antonio, Zanette, Régis A., Santos, Luciana D. dos, Guecheva, Temenouga Nikolova, Machado, Miriana, Klein-Júnior, Luiz Carlos, Dantas, Andrea dos Santos, Mello, Fernanda B. de

“…The present study aimed to investigate the in vitro mutagenic activity of Origanum majorana essential oil. The most abundant compounds identified by GC-MS were…”
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Chemical composition, immunostimulatory, cytotoxic and antiparasitic activities of the essential oil from Brazilian red propolis by Sena-Lopes, Ângela, Bezerra, Francisco Silvestre Brilhante, das Neves, Raquel Nascimento, de Pinho, Rodrigo Barros, Silva, Mara Thais de Oliveira, Savegnago, Lucielli, Collares, Tiago, Seixas, Fabiana, Begnini, Karine, Henriques, João Antonio Pêgas, Ely, Mariana Roesch, Rufatto, Luciane C, Moura, Sidnei, Barcellos, Thiago, Padilha, Francine, Dellagostin, Odir, Borsuk, Sibele

“…Most studies of Brazilian red propolis have explored the composition and biological properties of its ethanolic extracts. In this work, we chemically extracted…”
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Cytotoxic and genotoxic effects in mechanics occupationally exposed to diesel engine exhaust by León-Mejía, Grethel, Luna-Rodríguez, Ibeth, Trindade, Cristiano, Oliveros-Ortíz, Ludis, Anaya-Romero, Marco, Luna-Carrascal, Jaime, Navarro-Ojeda, Nebis, Ruiz-Benitez, Martha, Franco-Valencia, Karen, Da Silva, Juliana, Henriques, João Antônio Pêgas, Muñoz-Acevedo, Amner, Quintana-Sosa, M.

“…Diesel engine exhaust (DEE), which is the product of diesel combustion, is considered carcinogenic in humans. It comprises toxic gases, polycyclic aromatic…”
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SARS-CoV-2 mutations in Brazil: from genomics to putative clinical conditions by Timmers, Luis Fernando Saraiva Macedo, Peixoto, Julia Vasconcellos, Ducati, Rodrigo Gay, Bachega, José Fernando Ruggiero, de Mattos Pereira, Leandro, Caceres, Rafael Andrade, Majolo, Fernanda, da Silva, Guilherme Liberato, Anton, Débora Bublitz, Dellagostin, Odir Antônio, Henriques, João Antônio Pegas, Xavier, Léder Leal, Goettert, Márcia Inês, Laufer, Stefan

“…Due to the high rate of transmissibility, Brazil became the new COVID-19 outbreak epicenter and, since then, is being monitored to understand how SARS-CoV-2…”
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Titanium dioxide nanoparticles induce genotoxicity but not mutagenicity in golden mussel Limnoperna fortunei by Girardello, Francine, Custódio Leite, Camila, Vianna Villela, Izabel, da Silva Machado, Miriana, Luiz Mendes Juchem, André, Roesch-Ely, Mariana, Neves Fernandes, Andreia, Salvador, Mirian, Antonio Pêgas Henriques, João

“…•TiO2-NP can induce damage to DNA in haemocytes of Golden mussel.•No mutagenic effects were observed in Golden mussel cells after TiO2-NP exposure.•TiO2-NP…”
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Cytokinesis-block micronucleus cytome (CBMN-CYT) assay biomarkers and telomere length analysis in relation to inorganic elements in individuals exposed to welding fumes by Quintana-Sosa, Milton, León-Mejía, Grethel, Luna-Carrascal, Jaime, De moya, Yurina Sh, Rodríguez, Ibeth Luna, Acosta-Hoyos, Antonio, Anaya-Romero, Marco, Trindade, Cristiano, Narváez, Diana María, Restrepo, Helena Groot de, Dias, Johnny, Niekraszewicz, Liana, Garcia, Ana Letícia Hilario, Rohr, Paula, da Silva, Juliana, Henriques, João Antonio Pêgas

“…During the welding activities many compounds are released, several of these cause oxidative stress and inflammation and some are considered carcinogenic, in…”
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Selenium reduces bradykinesia and DNA damage in a rat model of Parkinson's disease by Ellwanger, Joel Henrique, B.Nutr, Molz, Patrícia, B.Nutr, Dallemole, Danieli Rosane, Pereira dos Santos, Ariana, Müller, Talise Ellwanger, Cappelletti, Lucas, Gonçalves da Silva, Manoela, Rech Franke, Silvia Isabel, Ph.D, Prá, Daniel, Ph.D, Pêgas Henriques, João Antonio, Ph.D

“…Abstract Objective The aim of this study was to explore the effects of selenium (Se) on locomotor activity and DNA damage in a rat model of Parkinson's disease…”
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DNA repair and metabolic gene polymorphisms affect genetic damage due to diesel engine exhaust exposure by León-Mejía, Grethel, Quintana-Sosa, Milton, de Moya Hernandez, Yurina, Rodríguez, Ibeth Luna, Trindade, Cristiano, Romero, Marco Anaya, Luna-Carrascal, Jaime, Ortíz, Ludis Oliveros, Acosta-Hoyos, Antonio, Ruiz-Benitez, Martha, Valencia, Karen Franco, Rohr, Paula, da Silva, Juliana, Henriques, João Antônio Pêgas

“…Diesel engine exhaust (DEE) is a complex mixture of toxic gases, halogenated aromatic hydrocarbons, alkyl polycyclic aromatic hydrocarbons, polycyclic aromatic…”
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Antioxidant and anti-mutagenic effects of ebselen in yeast and in cultured mammalian V79 cells by Miorelli, Simone Teresinha, Rosa, Renato Moreira, Moura, Dinara Jaqueline, Rocha, Jaqueline Cesar, Carneiro Lobo, Larissa Aline, Pêgas Henriques, João Antonio, Saffi, Jenifer

“…Ebselen has a wide spectrum of interesting therapeutic actions including antioxidant, cytoprotective, neuroprotective and anti-inflammatory activities. Since…”
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Systems chemo-biology analysis of DNA damage response and cell cycle effects induced by coal exposure by Torres-Ávila, Jose F., Espitia-Pérez, Lyda, Bonatto, Diego, Silva, Fernanda Rabaioli da, Oliveira, Iuri Marques de, Silva, Luís F.O., Corrêa, Dione Silva, Dias, Johnny Ferraz, Silva, Juliana da, Henriques, João Antonio Pêgas

“…Cell cycle alterations are among the principle hallmarks of cancer. Consequently, the study of cell cycle regulators has emerged as an important topic in…”
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