Search Results - "Henrique Nóbrega, Rafael"
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From Inflammation to Cutaneous Repair: Topical Application of Lupeol Improves Skin Wound Healing in Rats by Modulating the Cytokine Levels, NF-κB, Ki-67, Growth Factor Expression, and Distribution of Collagen Fibers
Published in International journal of molecular sciences (13-07-2020)“…Skin wound healing is a highly complex event that involves different mediators at the cellular and molecular level. Lupeol has been reported to possess…”
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Fsh Stimulates Spermatogonial Proliferation and Differentiation in Zebrafish via Igf3
Published in Endocrinology (Philadelphia) (01-10-2015)“…Growth factors modulate germ line stem cell self-renewal and differentiation behavior. We investigate the effects of Igf3, a fish-specific member of the igf…”
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Spermatogonial stem cell niche and spermatogonial stem cell transplantation in zebrafish
Published in PloS one (20-09-2010)“…Spermatogonial stem cells (SSCs) are the foundation of spermatogenesis, and reside within a specific microenvironment in the testes called "niche" which…”
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Cannabidiol improves Nile tilapia cichlid fish welfare
Published in Scientific reports (21-10-2022)“…Cannabidiol (CBD) is a substance derived from Cannabis sativa , widely studied in medicine for controlling neural diseases in humans. Besides the positive…”
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The Use of Menthol in Skin Wound Healing—Anti-Inflammatory Potential, Antioxidant Defense System Stimulation and Increased Epithelialization
Published in Pharmaceutics (09-11-2021)“…Wound healing involves inflammatory, proliferative, and remodeling phases, in which various cells and chemical intermediates are involved. This study aimed to…”
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Skin Wound Healing Potential and Mechanisms of the Hydroalcoholic Extract of Leaves and Oleoresin of Copaifera langsdorffii Desf. Kuntze in Rats
Published in Evidence-based complementary and alternative medicine (01-01-2017)“…The wound healing is a complex process which, sometimes, can be a problem in public health because of the possibility of physical disability or even death. Due…”
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Activity of the ovarian germinal epithelium in the freshwater catfish, Pimelodus maculatus (Teleostei: Ostariophysi: Siluriformes): Germline cysts, follicle formation and oocyte development
Published in Journal of morphology (1931) (01-11-2011)“…Distinct types of oogonia are found in the germinal epithelium that borders the ovarian lamellae of Pimelodus maculatus: A‐undifferentiated, A‐differentiated…”
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ceRNA crosstalk mediated by ncRNAs is a novel regulatory mechanism in fish sex determination and differentiation
Published in Genome research (01-08-2022)“…Competing endogenous RNAs (ceRNAs) are vital regulators of gene networks in mammals. The involvement of noncoding RNAs (ncRNAs) as ceRNA in genotypic sex…”
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Environmental impacts of COVID-19 treatment: Toxicological evaluation of azithromycin and hydroxychloroquine in adult zebrafish
Published in The Science of the total environment (10-10-2021)“…One of the most impact issues in recent years refers to the COVID-19 pandemic, the consequences of which thousands of deaths recorded worldwide, are still…”
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A83-01 and DMH1 effects in the zebrafish spermatogonial niche: Unraveling the roles of TGF-β and BMP signaling in the Fsh-mediated spermatogonial fate
Published in Gene (01-03-2024)“…Transforming growth factor-β (TGF-β) and bone morphogenetic protein (BMP) signaling has fundamental roles in the regulation of the stem cell niche for both…”
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Simulated climate change and atrazine contamination can synergistically impair zebrafish testicular function
Published in The Science of the total environment (10-10-2024)“…Elements that interfere with reproductive processes can have profound impacts on population and the equilibrium of ecosystems. Global warming represents the…”
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Intersex, Hermaphroditism, and Gonadal Plasticity in Vertebrates: Evolution of the Müllerian Duct and Amh Amhr2 Signaling
Published in Annual review of animal biosciences (15-02-2019)“…In vertebrates, sex organs are generally specialized to perform a male or female reproductive role. Acquisition of the Müllerian duct, which gives rise to the…”
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Estrogen-induced inhibition of spermatogenesis in zebrafish is largely reversed by androgen
Published in Journal of molecular endocrinology (01-05-2018)“…The hormonal regulation of spermatogenesis involves both gonadotropins and steroid hormones. Long-term in vivo exposure of adult zebrafish to estrogen impaired…”
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The influence of increased water temperature on the duration of spermatogenesis in a neotropical fish, Astyanax altiparanae (Characiformes, Characidae)
Published in Fish physiology and biochemistry (01-06-2021)“…In view of the established climate change scenario and the consequent changes in global temperature, it is essential to study its effects on animal…”
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Effects of GnRH and the dual regulatory actions of GnIH in the pituitary explants and brain slices of Astyanax altiparanae males
Published in General and comparative endocrinology (01-03-2019)“…[Display omitted] •cGnRH2 increased fshb and lhb mRNA levels in Astyanax altiparanae males.•zGnIH-3 decreased the cGnRH2-induced gonadotropin expression and…”
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Reproductive biology of the Amazonian amphibian fish the splash tetra Copella arnoldi with emphasis to histological characterization
Published in Acta zoologica (Stockholm) (01-07-2023)“…This study describes important components of the reproductive biology of the Amazonian amphibian fish Copella arnoldi. The species sex ratio biased to female…”
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Editorial: Animal models for pharmacological investigation of treatments and diagnostics for diseases
Published in Frontiers in cell and developmental biology (03-10-2022)Get full text
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Cyp17a1 and Cyp19a1 in the zebrafish testis are differentially affected by oestradiol
Published in Journal of endocrinology (01-03-2013)“…Oestrogens can affect expression of genes encoding steroidogenic enzymes in fish gonads. However, little information is available on their effects at the…”
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Time-efficient germ cell transplantation from goldfish ( Carassius auratus ) into adult common carp ( Cyprinus carpio )
Published in Animal reproduction (01-01-2024)“…Germ cell transplantation in fish is a promising technique for surrogate broodstock parents with broader application in aquaculture and conserving endangered…”
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Growth performance, reproductive status, and chromosomal instability in triploid Nile tilapias
Published in Animal reproduction (01-01-2024)“…Reproductive control is one of the biggest challenges in tilapia production and triploidy was developed as an alternative to sterilization. In general,…”
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