Search Results - "Henrique, D.M."

Antimicrobial and enhancement of the antibiotic activity by phenolic compounds: Gallic acid, caffeic acid and pyrogallol by Lima, Valéria N., Oliveira-Tintino, Cícera D.M., Santos, Enaide S., Morais, Luís P., Tintino, Saulo R., Freitas, Thiago S., Geraldo, Yuri S., Pereira, Raimundo L.S., Cruz, Rafael P., Menezes, Irwin R.A., Coutinho, Henrique D.M.

“…The indiscriminate use of antimicrobial drugs has increased the spectrum of exposure of these organisms. In our studies, these phenolic compounds were…”
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Inhibition of Efflux Pumps by Monoterpene (α-pinene) and Impact on Staphylococcus aureus Resistance to Tetracycline and Erythromycin by Freitas, Priscilla R, de Araújo, Ana Carolina J, Barbosa, Cristina R, Muniz, Débora F, Tintino, Saulo R, Ribeiro-Filho, Jaime, Siqueira Júnior, José P, Filho, José M B, de Sousa, Gabriela R, Coutinho, Henrique D M

“…Infectious diseases have been responsible for an increasing number of deaths worldwide. Staphylococcus aureus has been recognized as one of the most notable…”
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Modulation of Drug Resistance by Limonene: Inhibition of Efflux Pumps in Staphylococcus aureus Strains RN-4220 and IS-58 by de Araújo, Ana C J, Freitas, Priscilla R, Dos Santos Barbosa, Cristina R, Muniz, Débora F, Ribeiro-Filho, Jaime, Tintino, Saulo R, Júnior, José P S, Filho, José M B, de Sousa, Gabriela R, Coutinho, Henrique D M

“…This study aimed to investigate the potential of limonene as an efflux pump (EP) inhibitor in Staphylococcus aureus strains, RN-4220 and IS-58, which carry EPs…”
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Physico-chemical characterization and antibacterial activity of inclusion complexes of Hyptis martiusii Benth essential oil in β-cyclodextrin by Andrade, Tatianny A, Freitas, Thiago S, Araújo, Francielly O, Menezes, Paula P, Dória, Grace Anne A, Rabelo, Alessandra S, Quintans-Júnior, Lucindo J, Santos, Márcio R.V, Bezerra, Daniel P, Serafini, Mairim R, Menezes, Irwin Rose A, Nunes, Paula Santos, Araújo, Adriano A.S, Costa, Maria S, Campina, Fábia F, Santos, Antonia T.L, Silva, Ana R.P, Coutinho, Henrique D.M

“…Abstract Cyclodextrins (CDs) have been used as important pharmaceutical excipients for improve the physicochemical properties of the drugs of low solubility as…”
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Antiemetic activity of trans-ferulic acid possibly through muscarinic receptors interaction pathway: In vivo and in silico study by Bhuia, Md. Shimul, Kamli, Hossam, Islam, Tawhida, Sonia, Fatema Akter, Kazi, Md. Azim, Siam, Md. Sajjad Hossain, Rahman, Naimur, Bappi, Mehedi Hasan, Mia, Md. Nayem, Hossen, Md. Munnaf, Lucetti, Daniel Luna, Oliveira, Paulo Leonardo Celestino, Coutinho, Henrique D.M., Islam, Muhammad Torequl

“…Current study was conducted to assess the effectiveness of the polyphenol trans-ferulic acid (TFA) as an antiemetic agent using in vivo and in silico methods…”
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Evaluation of the tannic acid inhibitory effect against the NorA efflux pump of Staphylococcus aureus by Tintino, Saulo R., Oliveira-Tintino, Cícera D.M., Campina, Fábia F., Silva, Raimundo L.P., Costa, Maria do S., Menezes, Irwin R.A., Calixto-Júnior, João T., Siqueira-Junior, José P., Coutinho, Henrique D.M., Leal-Balbino, Tereza C., Balbino, Valdir Q.

“…During the early periods of antibiotic usage, bacterial infections were considered tamed. However, widespread antibiotic use has promoted the emergence of…”
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LC–MS analysis and cytoprotective effect against the mercurium and aluminium toxicity by bioactive products of Psidium brownianum Mart. ex DC by Sobral-Souza, Celestina E., Silva, Ana R.P., Leite, Nadghia F., Costa, José G.M., Menezes, Irwin R.A., Cunha, Francisco A.B., Rolim, Larissa A., Coutinho, Henrique D.M.

“…•The P. brownianum extract and its fractions have cytoprotective properties against mercury toxicity.•The P. brownianum extract and its fractions have…”
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Thiazine-derived compounds in inhibiting efflux pump in Staphylococcus aureus K2068, mepA gene expression, and membrane permeability alteration by Freitas, Priscilla R., de Araújo, Ana C.J., Araújo, Isaac M., de Almeida, Ray S., Borges, João A.O., Paulo, Cícera L.R., Oliveira-Tintino, Cícera D.M., Miranda, Gustavo M., Araújo-Neto, José B., Nascimento, Igor J.S., Araújo-Júnior, João X., Silva, Julia M.A., Balbino, Tereza C.L., Silva-Júnior, Edeildo F., Aquino, Thiago M., Mendonca-Junior, Francisco J.B., Marinho, Emmanuel S., Santos, Hélcio S., Lima, Clara Mariana Gonçalves, Obaidullah, Ahmad J., Bin Emran, Talha, Cunha, Francisco A.B., Menezes, Irwin R.A., Tintino, Saulo R., Coutinho, Henrique D.M.

“…Staphylococcus aureus is a bacterium responsible for resistance to multiple drugs and the efflux system is widely studied among the resistance mechanisms…”
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Cytotoxic and anti-kinetoplastid potential of the essential oil of Alpinia speciosa K. Schum by Pereira, Pedro S., Maia, Ana J., Duarte, Antônia E., Oliveira-Tintino, Cícera Datiane M., Tintino, Saulo R., Barros, Luiz M., Vega-Gomez, Maria C., Rolón, Miriam, Coronel, Cathia, Coutinho, Henrique D.M., da Silva, Teresinha G.

“…Alpinia speciosa K. Schum, known as colônia (colony), is native to tropical Asia and found in parts of tropical America. Its leaves are used to wrap food,…”
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Berberis Plants-Drifting from Farm to Food Applications, Phytotherapy, and Phytopharmacology by Salehi, Bahare, Selamoglu, Zeliha, Sener, Bilge, Kilic, Mehtap, Kumar Jugran, Arun, de Tommasi, Nunziatina, Sinisgalli, Chiara, Milella, Luigi, Rajkovic, Jovana, Flaviana B Morais-Braga, Maria, F Bezerra, Camila, E Rocha, Janaína, D M Coutinho, Henrique, Oluwaseun Ademiluyi, Adedayo, Khan Shinwari, Zabta, Ahmad Jan, Sohail, Erol, Ebru, Ali, Zulfiqar, Adrian Ostrander, Elise, Sharifi-Rad, Javad, de la Luz Cádiz-Gurrea, María, Taheri, Yasaman, Martorell, Miquel, Segura-Carretero, Antonio, Cho, William C

“…The genus includes about 500 different species and commonly grown in Europe, the United States, South Asia, and some northern areas of Iran and Pakistan…”
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Direct antibacterial and antibiotic resistance modulatory activity of chalcones synthesized from the natural product 2-hydroxy-3,4,6-trimethoxyacetophenone by Freitas, Thiago Sampaio de, Xavier, Jayze da Cunha, Pereira, Raimundo L S, Rocha, Janaina E, Muniz, Dédora F, da Silva, Priscila T, da Hora, João P, Dos Santos, Hélcio S, Bandeira, Paulo N, Nogueira, Carlos E S, Teixeira, Alexandre M R, Coutinho, Henrique D M

“…Antibiotic for clinical use lose its effectiveness over time due to bacterial resistance. In this work, four chalcones with modifications in their ligands were…”
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Trypanocide, antileishmania and cytotoxic activities of the essential oil from Rosmarinus officinalis L in vitro by Pereira, Pedro S., Maia, Ana J., Tintino, Saulo R., Oliveira-Tintino, Cícera Datiane de M., Raulino, Iranir Sâmya de S., Vega, Maria C., Rolón, Miriam, Coronel, Cathia, Barros, Luiz Marivando, Duarte, Antônia Eliene, de Menezes, Irwin R.A., Coutinho, Henrique D.M., da Silva, Teresinha G.

“…•The essential oil of Rosmarinus officinalis present as major class of compounds monoterpens.•The main compound of the EO of R. officinalis are α-pynene…”
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Pharmacological effects of a complex α-bisabolol/β-cyclodextrin in a mice arthritis model with involvement of IL-1β, IL-6 and MAPK by Heimfarth, Luana, Rezende, Marília Matos, Pereira, Erik Willyame Menezes, Passos, Fabiolla Rocha Santos, Monteiro, Brenda Souza, Santos, Tiffany Karoline Barroso, Lima, Natália Teles, Souza, Isana Carla Leal, de Albuquerque Junior, Ricardo Luiz Cavalcanti, de Souza Siqueira Lima, Pollyana, de Souza Araújo, Adriano Antunes, Quintans Júnior, Lucindo José, Kim, Bonglee, Coutinho, Henrique D.M., de Souza Siqueira Quintans, Jullyana

“…Inflammatory arthritis is the most prevalent chronic inflammatory disease worldwide. The pathology of the disease is characterized by increased inflammation…”
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In vivo and in silico studies of membrane-stabilizing and clot lysis activities of Trachyspermum ammi by Akbor, Md. Showkoth, Haque, Mst. Farjanamul, Rahman, Ahmmed Zunaed, Shill, Manik Chandra, Kamli, Hossam, Tahim, Catarina Martins, Neto, Ivo Cavalcante Pita, Coutinho, Henrique D.M., Islam, Muhammad Torequl

“…•T. ammi showed membrane-stabilizing activity in HRBCs in an in vitro test.•This may be possible by reducing inflammatory mediators.•ETA also exhibited clot…”
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Antiparasitic effect of the Psidium guajava L. (guava) and Psidium brownianum MART. EX DC. (araçá-de-veado) extracts by Machado, Antonio J.T., Santos, Antonia T.L., Martins, Gioconda M.A.B., Cruz, Rafael P., Costa, Maria do S., Campina, Fábia F., Freitas, Maria A., Bezerra, Camila F., Leal, Antonio L.A.B., Carneiro, Joara N.P., Coronel, Cathia, Rolón, Miriam, Gómez, Celeste V., Coutinho, Henrique D.M., Morais-Braga, Maria F.B.

“…In the search for new therapeutic agents against neglected diseases, both aqueous and hydroethanolic extracts from Psidium guajava L. and P. brownianum Mart ex…”
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Enhancement of the antibiotic activity of aminoglycosides by alpha-tocopherol and other cholesterol derivates by Andrade, Jacqueline C, Morais-Braga, Maria Flaviana B, Guedes, Glaucia M.M, Tintino, Saulo R, Freitas, Maria A, Menezes, Irwin R.A, Coutinho, Henrique D.M

“…Abstract Alpha-tocopherol, one of the most abundant isoforms of vitamin E, is a biologically active liposoluble vitamin and potent antioxidant. It occurs…”
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Docking, characterization and investigation of β-cyclodextrin complexed with citronellal, a monoterpene present in the essential oil of Cymbopogon species, as an anti-hyperalgesic agent in chronic muscle pain model by Santos, Priscila L., Brito, Renan G., Oliveira, Marlange A., Quintans, Jullyana S.S., Guimarães, Adriana G., Santos, Márcio R.V., Menezes, Paula P., Serafini, Mairim R., Menezes, Irwin R.A., Coutinho, Henrique D.M., Araújo, Adriano A.S., Quintans-Júnior, Lucindo J.

“…Citronellal (CT) is a monoterpene with antinociceptive acute effect. β-Cyclodextrin (βCD) has enhanced the analgesic effect of various substances. To evaluate…”
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Enhancement of aminoglycosides and β-lactams antibiotic activity by essential oil of Lippia sidoides Cham. and the Thymol by Veras, Helenicy N.H., Rodrigues, Fabíola F.G., Botelho, Marco A., Menezes, Irwin R.A., Coutinho, Henrique D.M., Costa, José G.M.

“…Natural products from plants can alter the effect of antibiotics, by increasing or reducing its activity. Lippia sidoides Cham. (Verbenaceae) is a bush found…”
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Phytotoxicity reduction of the mercury chloride effect by natural products from Eugenia jambolana Lam.: A new strategy against the toxic metal pollution by Sobral - Souza, Celestina E., Silva, Ana R.P., Leite, Nadghia F., Rocha, Janaina E., Sousa, Amanda K., Costa, José G.M., Menezes, Irwin R.A., Cunha, Francisco A.B., Rolim, Larissa A., Coutinho, Henrique D.M.

“…The objective of this work was to evaluate the antioxidant, metal chelating and cytoprotective activity of the Eugenia jambolana Lam. extract, as well as of…”
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Enhancement of orofacial antinociceptive effect of carvacrol, a monoterpene present in oregano and thyme oils, by β-cyclodextrin inclusion complex in mice by Silva, Juliane C, Almeida, Jackson R.G.S, Quintans, Jullyana S.S, Gopalsamy, Rajiv Gandhi, Shanmugam, Saravanan, Serafini, Mairim Russo, Oliveira, Maria R.C, Silva, Bruno A.F, Martins, Anita O.B.P.B, Castro, Fyama F, Menezes, Irwin R.A, Coutinho, Henrique D.M, Oliveira, Rita C.M, Thangaraj, Parimelazhagan, Araújo, Adriano A.S, Quintans-Júnior, Lucindo J

“…Abstract Orofacial pain is associated with diagnosis of chronic pain of head, face, mouth, neck and all the intraoral structures. Carvacrol, a naturally…”
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