Search Results - "Henriksen, Jørn"
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Preamplification with dUTP and Cod UNG Enables Elimination of Contaminating Amplicons
Published in International journal of molecular sciences (16-10-2018)“…Analyzing rare DNA and RNA molecules in limited sample sizes, such as liquid biopsies and single cells, often requires preamplification, which makes downstream…”
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2
Conditional expression of retrovirally delivered anti-MYCN shRNA as an in vitro model system to study neuronal differentiation in MYCN-amplified neuroblastoma
Published in BMC developmental biology (03-01-2011)“…Neuroblastoma is a childhood cancer derived from immature cells of the sympathetic nervous system. The disease is clinically heterogeneous, ranging from…”
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3
MYCN-regulated miRNA-92 inhibits secretion of the tumor suppressor DICKKOPF-3 (DKK3) in neuroblastoma
Published in Carcinogenesis (New York) (01-07-2011)“…The MYCN oncogene is frequently amplified in neuroblastoma. It is one of the most consistent markers of bad prognosis for this disease. Dickkopf-3 (DKK3) is a…”
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4
A Staphylococcus aureus TIR Domain Protein Virulence Factor Blocks TLR2-Mediated NF-κB Signaling
Published in Journal of innate immunity (2014)“…Signaling through Toll-like receptors (TLRs), crucial molecules in the induction of host defense responses, requires adaptor proteins that contain a…”
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5
Inhibition of mir-21, which is up-regulated during MYCN knockdown-mediated differentiation, does not prevent differentiation of neuroblastoma cells
Published in Differentiation (London) (2011)“…Neuroblastoma is a malignant childhood tumour arising from precursor cells of the sympathetic nervous system. Genomic amplification of the MYCN oncogene is…”
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6
Identification of target genes for wild type and truncated HMGA2 in mesenchymal stem-like cells
Published in BMC cancer (25-06-2010)“…The HMGA2 gene, coding for an architectural transcription factor involved in mesenchymal embryogenesis, is frequently deranged by translocation and/or…”
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7
Comparison of RNAi efficiency mediated by tetracycline-responsive H1 and U6 promoter variants in mammalian cell lines
Published in Nucleic acids research (01-05-2007)“…Conditional expression of short hairpin RNAs (shRNAs) to knock down target genes is a powerful tool to study gene function. The most common inducible…”
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Amplification and overexpression of COPS3 in osteosarcomas potentially target TP53 for proteasome-mediated degradation
Published in Oncogene (14-08-2003)“…In sarcomas, the TP53 tumour suppressor pathway may be altered either by TP53 mutations or by amplification of MDM2, encoding a protein that inhibits TP53 and…”
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Global Gene Expression Profiling of Human Osteosarcomas Reveals Metastasis-Associated Chemokine Pattern
Published in Sarcoma (2012)“…Global gene expression analysis was performed on a panel of 23 osteosarcoma samples of primary and metastatic origin using the Applied Biosystems Gene…”
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10
RNA reprogramming of α‐mannosidase mRNA sequences in vitro by myxomycete group IC1 and IE ribozymes
Published in The FEBS journal (01-06-2006)“…Trans‐splicing group I ribozymes have been introduced in order to mediate RNA reprogramming (including RNA repair) of therapeutically relevant RNA transcripts…”
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11
Inhibition of gene function in mammalian cells using short-hairpin RNA (shRNA)
Published in Methods in molecular biology (Clifton, N.J.) (2011)“…RNAi is now the preferred method for silencing gene expression in a variety of systems. In this chapter we describe the procedure for applying short-hairpin…”
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12
Amplification and overexpression of PRUNE in human sarcomas and breast carcinomas : a possible mechanism for altering the nm23-H1 activity
Published in Oncogene (18-10-2001)“…PRUNE, the human homologue of the Drosophila gene, is located in 1q21.3, a region highly amplified in human sarcomas, malignant tumours of mesenchymal origin…”
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13
Ectopic sequences from truncated HMGIC in liposarcomas are derived from various amplified chromosomal regions
Published in Genes chromosomes & cancer (01-07-2001)“…The HMGIC gene codes for an architectural transcription factor frequently rearranged by translocation in lipomas and other benign mesenchymal tumors. In…”
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14
Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma
Published in British journal of cancer (12-07-2011)“…Background: MicroRNAs (miRNAs) regulate expression of many cancer-related genes through posttranscriptional repression of their mRNAs. In this study we…”
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15
Adolescence asthma and transition
Published in The clinical respiratory journal (01-04-2009)Get more information
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16
Accuracy of whole-body plethysmography requires biological calibration
Published in Chest (01-06-2009)“…Specific airway resistance (sRaw) measured by whole-body plethysmography in young children is increasingly used in research and clinical practice. The method…”
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17
A Staphylococcus aureus TIR Domain Protein Virulence Factor Blocks TLR2-Mediated NF-[kappa]B Signaling
Published in Journal of innate immunity (01-06-2014)“…Signaling through Toll-like receptors (TLRs), crucial molecules in the induction of host defense responses, requires adaptor proteins that contain a…”
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18
RNA reprogramming of [alpha]-mannosidase mRNA sequences in vitro by myxomycete group IC1 and IE ribozymes
Published in The FEBS journal (01-06-2006)“…Trans -splicing group I ribozymes have been introduced in order to mediate RNA reprogramming (including RNA repair) of therapeutically relevant RNA…”
Get full text
Journal Article -
19
Global Gene Expression Profiling of Human Osteosarcomas Reveals Metastasis-Associated Chemokine Pattern
Published in Sarcoma (2012)“…Global gene expression analysis was performed on a panel of 23 osteosarcoma samples of primary and metastatic origin using the Applied Biosystems Gene…”
Get full text
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20
Going to extremes – a metagenomic journey into the dark matter of life
Published in FEMS microbiology letters (24-06-2021)“…ABSTRACT The Virus-X—Viral Metagenomics for Innovation Value—project was a scientific expedition to explore and exploit uncharted territory of genetic…”
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