Search Results - "Henrik Nausch"

Simulation and optimization of nutrient uptake and biomass formation using a multi-parameter Monod-type model of tobacco BY-2 cell suspension cultures in a stirred-tank bioreactor by Nausch, Henrik, Baldan, Marco, Teichert, Katrin, Lutz, Jannik, Claussen, Carsten, Bortz, Michael, Buyel, Johannes Felix

“…Tobacco ( ) cv Bright Yellow-2 (BY-2) cell suspension cultures enable the rapid production of complex protein-based biopharmaceuticals but currently achieve…”
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Direct Delivery of Health Promoting β-Asp-Arg Dipeptides via Stable Co-expression of Cyanophycin and the Cyanophycinase CphE241 in Tobacco Plants by Nausch, Henrik, Dorn, Mandy, Frolov, Andrej, Hoedtke, Sandra, Wolf, Petra, Broer, Inge

“…Feed supplementation with β-arginine-aspartate dipeptides (β-Asp-Arg DP) shows growth promoting effects in feeding trials with fish and might also be…”
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High-level transient expression of ER-targeted human interleukin 6 in Nicotiana benthamiana by Nausch, Henrik, Mikschofsky, Heike, Koslowski, Roswitha, Meyer, Udo, Broer, Inge, Huckauf, Jana

“…Tobacco plants can be used to express recombinant proteins that cannot be produced in a soluble and active form using traditional platforms such as Escherichia…”
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Recombinant production of human interleukin 6 in Escherichia coli by Nausch, Henrik, Huckauf, Jana, Koslowski, Roswitha, Meyer, Udo, Broer, Inge, Mikschofsky, Heike

“…In this study, we compared basic expression approaches for the efficient expression of bioactive recombinant human interleukin-6 (IL6), as an example for a…”
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Seed- and leaf-based expression of FGF21-transferrin fusion proteins for oral delivery and treatment of non-alcoholic steatohepatitis by Hou, Hsuan-Wu, Bishop, Christopher A., Huckauf, Jana, Broer, Inge, Klaus, Susanne, Nausch, Henrik, Buyel, Johannes F.

“…Non-alcoholic steatohepatitis (NASH) is a global disease with no effective medication. The fibroblast growth factor 21 (FGF21) can reverse this liver…”
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Expression and subcellular targeting of human complement factor C5a in Nicotiana species by Nausch, Henrik, Mikschofsky, Heike, Mischofsky, Heike, Koslowski, Roswitha, Meyer, Udo, Broer, Inge, Huckauf, Jana

“…We evaluated transgenic tobacco plants as an alternative to Escherichia coli for the production of recombinant human complement factor 5a (C5a). C5a has not…”
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Sustainable Production of the Cyanophycin Biopolymer in Tobacco in the Greenhouse and Field by Huckauf, Jana, Brandt, Boudewijn P., Dezar, Carlos, Nausch, Henrik, Hauerwaas, Antoniya, Weisenfeld, Ursula, Elshiewy, Ossama, Rua, Melina, Hugenholtz, Jeroen, Wesseler, Justus, Cingiz, Kutay, Broer, Inge

“…The production of biodegradable polymers as coproducts of other commercially relevant plant components can be a sustainable strategy to decrease the carbon…”
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Corrigendum: Sustainable production of the cyanophycin biopolymer in tobacco in the greenhouse and field by Huckauf, Jana, Brandt, Boudewijn P., Dezar, Carlos, Nausch, Henrik, Hauerwaas, Antoniya, Weisenfeld, Ursula, Elshiewy, Ossama, Rua, Melina, Hugenholtz, Jeroen, Wesseler, Justus, Cingiz, Kutay, Broer, Inge

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Paternal inheritance of plastid-encoded transgenes in Petunia hybrida in the greenhouse and under field conditions by Horn, Patricia, Nausch, Henrik, Baars, Susanne, Schmidtke, Jörg, Schmidt, Kerstin, Schneider, Anja, Leister, Dario, Broer, Inge

“…•First proof of PMGF of a plastid-encoded transgene in the field.•Transgene integration influenced pollen quality differently in greenhouse and field.•PMGF…”
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Cyanophycinase CphE from P. alcaligenes produced in different compartments of N. benthamiana degrades high amounts of cyanophycin in plant extracts by Nausch, Henrik, Broer, Inge

“…One of the major constraints in pig and poultry farming is the supply of protein-rich forage, containing sufficient amounts of key amino acids such as arginine…”
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Cryopreservation of plant cell cultures – Diverse practices and protocols by Nausch, Henrik, Buyel, Johannes F.

“…•Slow freezing can be simple but may require controlled cooling rates 9•Vitrification relies on sophisticated sample handling but no specialized equipment…”
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Peculiarities and impacts of expression of bacterial cyanophycin synthetases in plants by Nausch, Henrik, Huckauf, Jana, Broer, Inge

“…Cyanophycin (CP) can be successfully produced in plants by the ectopic expression of the CphA synthetase from Thermosynechococcus elongatus BP-1 (Berg et al…”
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Expression of CphB- and CphE-type cyanophycinases in cyanophycin-producing tobacco and comparison of their ability to degrade cyanophycin in plant and plant extracts by Ponndorf, Daniel, Broer, Inge, Nausch, Henrik

“…Increasing the arginine (Arg) content in plants used as feed or food is of interest, since the supplementation of food with conditionally essential Arg has…”
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Public funded field trials with transgenic plants in Europe: a comparison between Germany and Switzerland by Nausch, Henrik, Sautter, Christof, Broer, Inge, Schmidt, Kerstin

“…Graphical abstract…”
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Tobacco as platform for a commercial production of cyanophycin by Nausch, Henrik, Hausmann, Tina, Ponndorf, Daniel, Hühns, Maja, Hoedtke, Sandra, Wolf, Petra, Zeyner, Annette, Broer, Inge

“…•Production of cyanophycin in the commercial N. tabacum cultivars BG and VG.•Cyanophycin yielded up to 9.4% per dry weight (DW) in hyrbids of transgenic pH…”
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Stable production of cyanophycinase in Nicotiana benthamiana and its functionality to hydrolyse cyanophycin in the murine intestine by Ponndorf, Daniel, Ehmke, Sven, Walliser, Benjamin, Thoss, Kerstin, Unger, Christoph, Görs, Solvig, Daş, Gürbüz, Metges, Cornelia C., Broer, Inge, Nausch, Henrik

“…Summary Food supplementation with the conditionally essential amino acid arginine (Arg) has been shown to have nutritional benefits. Degradation of cyanophycin…”
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Correction: Expression and Subcellular Targeting of Human Complement Factor C5a in Nicotiana species by Nausch, Henrik, Mikschofsky, Heike, Koslowski, Roswitha, Meyer, Udo, Broer, Inge, Huckauf, Jana

“…(2012) Expression and Subcellular Targeting of Human Complement Factor C5a in Nicotiana species. PLoS ONE 7(12): e53023. doi:10.1371/journal.pone.0053023…”
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An endoplasmic reticulum (ER)-directed fusion protein comprising a bacterial subtilisin domain and the human cytokine interleukin 6 is efficiently cleaved in planta by Henrik, Nausch, Heike, Mikschofsky, Roswitha, Koslowski, Alain, Steinmann, Udo, Meyer, Inge, Broer, Jana, Huckauf

“…A major limitation of plant bioreactors is the lack of suitable and cost-effective purification methods for the extraction of pharmaceutical-grade proteins. In…”
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Correction: Expression and Subcellular Targeting of Human Complement Factor C5a in by Henrik Nausch, Heike Mikschofsky, Roswitha Koslowski, Udo Meyer, Inge Broer, Jana Huckauf

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