Search Results - "Henriet, Patrick"
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Regulation of matrix metalloproteinases activity studied in human endometrium as a paradigm of cyclic tissue breakdown and regeneration
Published in Biochimica et biophysica acta (01-01-2012)“…When abundant and activated, matrix metalloproteinases (MMPs, or matrixins) degrade most, if not all, constituents of the extracellular matrix (ECM). The…”
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Chronic liver injury promotes hepatocarcinoma cell seeding and growth, associated with infiltration by macrophages
Published in Cancer science (01-07-2018)“…Ninety percent of hepatocarcinoma (HCC) develops in a chronically damaged liver. Interactions between non‐tumor stromal components, especially macrophages, and…”
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Identification and implication of tissue-enriched ligands in epithelial–endothelial crosstalk during pancreas development
Published in Scientific reports (21-07-2022)“…Development of the pancreas is driven by an intrinsic program coordinated with signals from other cell types in the epithelial environment. These intercellular…”
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Targeting cholesterol impairs cell invasion of all breast cancer types
Published in Cancer cell international (10-01-2024)“…Breast cancer clinical outcome relies on its intrinsic molecular subtype and mortality is almost exclusively due to metastasis, whose mechanism remains…”
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Matrix metalloproteinase-27 is expressed in CD163+/CD206+ M2 macrophages in the cycling human endometrium and in superficial endometriotic lesions
Published in Molecular human reproduction (01-08-2014)“…Matrix metalloproteinases (MMPs) are key enzymes involved in extracellular matrix remodelling. In the human endometrium, the expression and activity of several…”
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Down-Regulation of the Histone Methyltransferase EZH2 Contributes to the Epigenetic Programming of Decidualizing Human Endometrial Stromal Cells
Published in Molecular endocrinology (Baltimore, Md.) (01-11-2011)“…Differentiation of human endometrial stromal cells (HESC) into decidual cells represents a highly coordinated process essential for embryo implantation. We…”
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Endogenous sphingomyelin segregates into submicrometric domains in the living erythrocyte membrane[S]
Published in Journal of lipid research (01-07-2014)“…We recently reported that trace insertion of exogenous fluorescent (green BODIPY) analogs of sphingomyelin (SM) into living red blood cells (RBCs), partially…”
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LRP-1 promotes cancer cell invasion by supporting ERK and inhibiting JNK signaling pathways
Published in PloS one (14-07-2010)“…The low-density lipoprotein receptor-related protein-1 (LRP-1) is an endocytic receptor mediating the clearance of various extracellular molecules involved in…”
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In-Depth Analysis of the Pancreatic Extracellular Matrix during Development for Next-Generation Tissue Engineering
Published in International journal of molecular sciences (17-06-2023)“…The pancreas is a complex organ consisting of differentiated cells and extracellular matrix (ECM) organized adequately to enable its endocrine and exocrine…”
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Variability of extracellular vesicle release during storage of red blood cell concentrates is associated with differential membrane alterations, including loss of cholesterol-enriched domains
Published in Frontiers in physiology (20-06-2023)“…Transfusion of red blood cell concentrates is the most common medical procedure to treat anaemia. However, their storage is associated with development of…”
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Conclusions, suivies d’une bibliographie de cent titres pour approfondir l’histoire du corps au Moyen Âge
Published in Revue des langues romanes (2019)Get full text
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AG-205 Upregulates Enzymes Involved in Cholesterol Biosynthesis and Steroidogenesis in Human Endometrial Cells Independently of PGRMC1 and Related MAPR Proteins
Published in Biomolecules (Basel, Switzerland) (06-10-2021)“…An inappropriate response to progestogens in the human endometrium can result in fertility issues and jeopardize progestin-based treatments against pathologies…”
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Cholesterol and Sphingomyelin Polarize at the Leading Edge of Migrating Myoblasts and Involve Their Clustering in Submicrometric Domains
Published in Biomolecules (Basel, Switzerland) (07-02-2023)“…Myoblast migration is crucial for myogenesis and muscular tissue homeostasis. However, its spatiotemporal control remains elusive. Here, we explored the…”
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Piezo1 Regulation Involves Lipid Domains and the Cytoskeleton and Is Favored by the Stomatocyte-Discocyte-Echinocyte Transformation
Published in Biomolecules (Basel, Switzerland) (01-01-2024)“…Piezo1 is a mechanosensitive ion channel required for various biological processes, but its regulation remains poorly understood. Here, we used erythrocytes to…”
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Human liver mesenchymal stem/progenitor cells inhibit hepatic stellate cell activation: in vitro and in vivo evaluation
Published in Stem cell research & therapy (05-06-2017)“…Progressive liver fibrosis leads to cirrhosis and end-stage liver disease. This disease is a consequence of strong interactions between matrix-producing…”
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Cellular uptake of proMMP-2:TIMP-2 complexes by the endocytic receptor megalin/LRP-2
Published in Scientific reports (28-06-2017)“…Matrix metalloproteinases (MMPs) are regulated at multiple transcriptional and post-transcriptional levels, among which receptor-mediated endocytic clearance…”
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Piezo1 Is Required for Myoblast Migration and Involves Polarized Clustering in Association with Cholesterol and GM1 Ganglioside
Published in Cells (Basel, Switzerland) (01-12-2023)“…A specific plasma membrane distribution of the mechanosensitive ion channel Piezo1 is required for cell migration, but the mechanism remains elusive. Here, we…”
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Spatiotemporal Coupling of Focal Extracellular Matrix Degradation and Reconstruction in the Menstrual Human Endometrium
Published in Endocrinology (Philadelphia) (01-11-2009)“…Coupling of focal degradation and renewal of the functional layer of menstrual endometrium is a key event of the female reproductive biology. The precise…”
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Rois en priere et oracle sibyllin. Une relecture de certaines scenes du reliquaire de San Millan de la Cogolla
Published in Studia historica. Ha. medieval (01-03-2016)“…Este trabajo trata de la representación de los reyes hispánicos en oración durante la plena Edad Media. El rey no se humillaba en la tradición asturiana y…”
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