Search Results - "Henricks, P A"

Airway hyper-responsiveness in allergic asthma in guinea-pigs is mediated by nerve growth factor via the induction of substance P: a potential role for trkA by De Vries, A., Engels, F., Henricks, P. A. J., Leusink-Muis, T., McGregor, G. P., Braun, A., Groneberg, D. A., Dessing, M. C., Nijkamp, F. P., Fischer, A.

“…Summary Background: The neurotrophin nerve growth factor (NGF) has been implicated as a mediator in allergic asthma. Direct evidence that inhibition of…”
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Antibodies directed against nerve growth factor inhibit the acute bronchoconstriction due to allergen challenge in guinea-pigs by De Vries, A., Engels, F., Henricks, P. A. J., Leusink-Muis, T., Fischer, A., Nijkamp, F. P.

“…Background We have previously demonstrated that the administration of nerve growth factor (NGF) to guinea‐pigs results in airway hyper‐responsiveness within 1…”
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Exogenous interleukin-16 inhibits antigen-induced airway hyper-reactivity, eosinophilia and Th2-type cytokine production in mice by De Bie, J. J., Jonker, E. H., Henricks, P. A. J., Hoevenaars, J., Little, F. F., Cruikshank, W. W., Nijkamp, F. P., Van Oosterhout, A. J. M.

“…Summary Background IL‐16 has been described as a natural soluble CD4‐ligand with immunosuppressive effects in vitro. However, little is known about the effect…”
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Cigarette smoke induces the release of CXCL-8 from human bronchial epithelial cells via TLRs and induction of the inflammasome by Mortaz, E., Henricks, P.A.J., Kraneveld, A.D., Givi, M.E., Garssen, J., Folkerts, G.

“…COPD is a chronic airway disease associated with inflammation and cigarette smoking. Airway epithelial cells are the first cells exposed to cigarette smoke…”
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Modulation of airway hyperresponsiveness and eosinophilia by selective histamine and 5‐HT receptor antagonists in a mouse model of allergic asthma by De Bie, J J., Henricks, P A J., Cruikshank, W W., Hofman, G, Jonker, E H., Nijkamp, F P., Van Oosterhout, A J M.

“…Since both histamine and 5‐hydroxytryptamine (5‐HT) can be released by murine mast cells, we investigated the possible role of these autacoids on airway…”
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A comparison of fixation methods on lung morphology in a murine model of emphysema by Braber, S, Verheijden, K A T, Henricks, P A J, Kraneveld, A D, Folkerts, G

“…Emphysema is characterized by enlargement of the alveoli, which is the most important parameter to assess the presence and severity of this disease. Alveolar…”
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Glutathione-conjugated toluene diisocyanate causes airway inflammation in sensitised mice by VALSTAR, D. L, SCHIJF, M. A, NIJKAMP, F. P, BLOKSMA, N, HENRICKS, P. A. J

“…Toluene diisocyanate (TDI) is a highly volatile compound that reacts readily with nucleophilic compounds, sulfhydryl groups in particular. Since the epithelial…”
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Increased cAMP levels in stimulated neutrophils inhibit their adhesion to human bronchial epithelial cells by Bloemen, P G, van den Tweel, M C, Henricks, P A, Engels, F, Kester, M H, van de Loo, P G, Blomjous, F J, Nijkamp, F P

“…Bronchial epithelial cells express the intercellular adhesion molecule-1 that mediates binding of activated neutrophils via interaction with Mac-1 and/or…”
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Peroxynitrite in airway diseases by SADEGHI-HASHJIN, G, FOLKERTS, G, HENRICKS, P. A. J, MUIJSERS, R. B. R, NIJKAMP, F. P

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Cell adhesion molecules and asthma by BLOEMEN, P. G. M, HENRICKS, P. A. J, NIJKAMP, F. P

“…Abstract only…”
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Mechanisms of beta-adrenergic receptor regulation in lungs and its implications for physiological responses by Nijkamp, F P, Engels, F, Henricks, P A, Van Oosterhout, A J

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Nerve Growth Factor Induces a Neurokinin-1 Receptor- Mediated Airway Hyperresponsiveness in Guinea Pigs by de VRIES, ANNICK, DESSING, MARK C, ENGELS, FERDI, HENRICKS, PAUL A. J, NIJKAMP, FRANS P

“…Because asthmatic patients show increased nerve growth factor (NGF) serum levels, we examined the effect of NGF on airway function. Intravenously administered…”
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Stimulation of both human bronchial epithelium and neutrophils is needed for maximal interactive adhesion by Bloemen, P G, Van den Tweel, M C, Henricks, P A, Engels, F, Van de Velde, M J, Blomjous, F J, Nijkamp, F P

“…It has become clear that the bronchial epithelium is not just a passive barrier but plays an active role in inflammation. It can produce several inflammatory…”
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Relaxation of guinea‐pig trachea by sodium nitroprusside: cyclic GMP and nitric oxide not involved by Sadeghi‐Hashjin, Gudarz, Folkerts, Gert, Henricks, Paul A.J., Loo, Peet G.F., Dik, Ilse E.M., Nijkamp, Frans P.

“…1 Sodium nitroprusside (SNP) completely relaxed the guinea‐pig isolated, perfused trachea in a concentration‐dependent manner. Although SNP was less potent by…”
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Peroxynitrite induces airway hyperresponsiveness in guinea pigs in vitro and in vivo by Sadeghi-Hashjin, G, Folkerts, G, Henricks, P A, Verheyen, A K, van der Linde, H J, van Ark, I, Coene, A, Nijkamp, F P

“…Peroxynitrite (ONOO-) is a cytotoxic product of the rapid reaction between nitric oxide and superoxide that may initiate inflammation. Isolated perfused…”
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Peroxynitrite: A two-faced metabolite of nitric oxide by Muijsers, Richard B.R., Folkerts, Gert, Henricks, Paul A.J., Sadeghi-Hashjin, Gudarz, Nijkamp, Frans P.

“…The discovery that nitric oxide (NO) reacts with Superoxide (O 2 −) forming peroxynitrite (ONOO −) (1) and the proof that this reaction occurs in vivo (2,3)…”
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Hypotensive effect of 13‐hydroxylinoleic acid in the rat: mediation via the release of a CGRP‐like mediator from capsaicin‐sensitive nerves by Heuven‐Nolsen, Dicky, Muis, Thea, Engels, Ferdi, Henricks, Paul A.J., Buckley, Theresa L., Nijkamp, Frans P.

“…1 The effect of 13‐hydroxylinoleic acid (13‐HODE) on changes in blood pressure in the rat was measured. 2 13‐HODE (0.1 −100 μg kg−1) had no direct eifect on…”
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Sodium cromoglycate and doxantrazole are oxygen radical scavengers by Sadeghi-Hashjin, G, Nijkamp, F.P, Henricks, P.A.J, Folkerts, G

“…The effects of two mast cell stabilisers, sodium cromoglycate (SCG) and doxantrazole, on the formation of reactive oxygen species (ROS) were studied…”
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Role of the epithelial layer in the generation of superoxide anion by the guinea-pig isolated trachea by Sadeghi-Hashjin, G., Henricks, P. A. J., Folkerts, G., Muis, T., Garssen, J., Nijkamp, F. P.

“…THE lucigenin-dependent chemiluminescence generation by guinea-pig isolated tracheal two rings preparations was studied. Tracheal preparations stimulated with…”
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Expression and modulation of adhesion molecules on human bronchial epithelial cells by Bloemen, P G, van den Tweel, M C, Henricks, P A, Engels, F, Wagenaar, S S, Rutten, A A, Nijkamp, F P

“…Epithelial damage in the airways is a feature often observed in patients with asthma and is probably caused by the interaction of epithelial cells with…”
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