Search Results - "Henrici De Angelis, Lucia"
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φBO1E, a newly discovered lytic bacteriophage targeting carbapenemase-producing Klebsiella pneumoniae of the pandemic Clonal Group 258 clade II lineage
Published in Scientific reports (01-06-2017)“…The pandemic dissemination of KPC carbapenemase-producing Klebsiella pneumoniae (KPC-KP) represents a major public health problem, given their extensive…”
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Resistance and virulence features of hypermucoviscous Klebsiella pneumoniae from bloodstream infections: Results of a nationwide Italian surveillance study
Published in Frontiers in microbiology (15-08-2022)“…Among Enterobacterales, Klebsiella pneumoniae (Kp) is one of the major opportunistic pathogens causing hospital-acquired infections. The most problematic…”
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Fighting MDR- Klebsiella pneumoniae Infections by a Combined Host- and Pathogen-Directed Therapeutic Approach
Published in Frontiers in immunology (14-02-2022)“…is an opportunistic pathogen that is very difficult to treat mainly due to its high propensity to acquire complex resistance traits. Notably, multidrug…”
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Resistome and virulome accretion in an NDM-1-producing ST147 sublineage of Klebsiella pneumoniae associated with an outbreak in Tuscany, Italy: a genotypic and phenotypic characterisation
Published in The Lancet. Microbe (01-03-2022)“…Carbapenemase-producing Enterobacterales (CPE), particularly those producing metallo-β-lactamases, are among the most challenging antibiotic-resistant…”
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Combined Host- and Pathogen-Directed Therapy for the Control of Mycobacterium abscessus Infection
Published in Microbiology spectrum (23-02-2022)“…Mycobacterium abscessus is the etiological agent of severe pulmonary infections in vulnerable patients, such as those with cystic fibrosis (CF), where it…”
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Identification of a Novel Plasmid Lineage Associated With the Dissemination of Metallo-β-Lactamase Genes Among Pseudomonads
Published in Frontiers in microbiology (02-07-2019)“…Acquisition of metallo-β-lactamases (MBLs) represents one of most relevant resistance mechanisms to all β-lactams, including carbapenems, ceftolozane and…”
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The lytic bacteriophage vB_EfaH_EF1TV, a new member of the Herelleviridae family, disrupts biofilm produced by Enterococcus faecalis clinical strains
Published in Journal of global antimicrobial resistance. (01-06-2020)“…[Display omitted] •EF1TV is a newly discovered lytic bacteriophage specific for Enterococcus faecalis.•Phage EF1TV is the fourth characterized member of the…”
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The Multifunctional Role of Poloxamer P338 as a Biofilm Disrupter and Antibiotic Enhancer: A Small Step forward against the Big Trouble of Catheter-Associated Escherichia coli Urinary Tract Infections
Published in Microorganisms (Basel) (31-08-2022)“…Poloxamer 338 (P338), a nonionic surfactant amphiphilic copolymer, is herein proposed as an anti-biofilm compound for the management of catheter-associated…”
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Characterization of vB_StuS_MMDA13, a Newly Discovered Bacteriophage Infecting the Agar-Degrading Species Sphingomonas turrisvirgatae
Published in Viruses (15-08-2020)“…Members of genus have gained a notable interest for their use in a wide range of biotechnological applications, ranging from bioremediation to the production…”
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Phage Resistance Is Associated with Decreased Virulence in KPC-Producing Klebsiella pneumoniae of the Clonal Group 258 Clade II Lineage
Published in Microorganisms (Basel) (06-04-2021)“…Phage therapy is now reconsidered with interest in the treatment of bacterial infections. A major piece of information for this application is the definition…”
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Application of Bacteriophages for Human Health: An Old Approach against Contemporary "Bad Bugs"
Published in Microorganisms (Basel) (22-02-2022)“…The breadth of the antimicrobial resistance (AMR) problem exposes humankind to serious threats, which could lead, in the near future, to a worrisome raising of…”
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mcr-1.2, a New mcr Variant Carried on a Transferable Plasmid from a Colistin-Resistant KPC Carbapenemase-Producing Klebsiella pneumoniae Strain of Sequence Type 512
Published in Antimicrobial agents and chemotherapy (01-09-2016)“…A novel mcr variant, named mcr-1.2, encoding a Gln3-to-Leu functional variant of MCR-1, was detected in a KPC-3-producing ST512 Klebsiella pneumoniae isolate…”
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Large Nosocomial Outbreak of Colistin-Resistant, Carbapenemase-Producing Klebsiella pneumoniae Traced to Clonal Expansion of an mgrB Deletion Mutant
Published in Journal of clinical microbiology (01-10-2015)“…We describe a large hospital outbreak (93 bloodstream infections) of colistin-resistant Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae…”
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Management of Meningitis Caused by Multi Drug-Resistant Acinetobacter Baumannii: Clinical, Microbiological and Pharmacokinetic Results in a Patient Treated with Colistin Methanesulfonate
Published in Mediterranean journal of hematology and infectious diseases (11-10-2015)“…This paper reports on a 71- year-old Caucasian male who underwent neurosurgery for an oligodendroglioma, followed by a cranial-sinus fistula and cerebrospinal…”
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Draft Genome Sequence of Proteus mirabilis NO-051/03, Representative of a Multidrug-Resistant Clone Spreading in Europe and Expressing the CMY-16 AmpC-Type β-Lactamase
Published in Genome announcements (Washington, DC) (11-02-2016)“…Proteus mirabilis NO-051/03, representative of a multidrug-resistant clone expressing the CMY-16 AmpC-type β-lactamase and circulating in Europe since 2003,…”
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Ceftolozane-Tazobactam Pharmacokinetics during Extracorporeal Membrane Oxygenation in a Lung Transplant Recipient
Published in Antimicrobial agents and chemotherapy (01-03-2019)Get full text
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Italian nationwide survey on Pseudomonas aeruginosa from invasive infections: activity of ceftolozane/tazobactam and comparators, and molecular epidemiology of carbapenemase producers
Published in Journal of antimicrobial chemotherapy (01-03-2018)“…Pseudomonas aeruginosa is a major cause of severe healthcare-associated infections and often shows MDR phenotypes. Ceftolozane/tazobactam is a new…”
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Phosphatidylserine Liposomes Reduce Inflammatory Response, Mycobacterial Viability, and HIV Replication in Coinfected Human Macrophages
Published in The Journal of infectious diseases (04-05-2022)“…Abstract Chronic immune activation is the key pathogenetic event of Mycobacterium tuberculosis-human immunodeficiency virus (HIV) coinfection. We assessed the…”
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Colistin Resistance Caused by Inactivation of the MgrB Regulator Is Not Associated with Decreased Virulence of Sequence Type 258 KPC Carbapenemase-Producing Klebsiella pneumoniae
Published in Antimicrobial agents and chemotherapy (01-04-2016)“…Using aGalleria mellonellaanimal model, we compared the virulence of two sequence type 258 (ST258) KPC-producingKlebsiella pneumoniaestrains, which were…”
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Infections caused by carbapenem-resistant Klebsiella pneumoniae with hypermucoviscous phenotype: A case report and literature review
Published in Virulence (17-11-2017)Get full text
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