Search Results - "Henrichs, Kelly F."

Outcomes Using a Conservative Versus Liberal Red Blood Cell Transfusion Strategy in Infants Requiring Cardiac Operation by Cholette, Jill M., MD, Swartz, Michael F., PhD, Rubenstein, Jeffrey, MD, Henrichs, Kelly F., MT(ASCP), Wang, Hongyue, PhD, Powers, Karen S., MD, Daugherty, L. Eugene, MD, Alfieris, George M., MD, Gensini, Francisco, MD, Blumberg, Neil, MD

“…Background The optimal hemoglobin for infants after cardiac operation is unknown. Red blood cells (RBCs) are commonly transfused to maintain high hemoglobin…”
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Providing ABO-identical platelets and cryoprecipitate to (almost) all patients: approach, logistics, and associated decreases in transfusion reaction and red blood cell alloimmunization incidence by Henrichs, Kelly F., Howk, Nedda, Masel, Debra S., Thayer, Mark, Refaai, Majed A., Kirkley, Scott A., Heal, Joanna M., Blumberg, Neil

“…BACKGROUND: There are multiple benefits to transfusing only ABO‐identical blood components. Historically our institution routinely transfused ABO‐nonidentical…”
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Prophylactic Preprocedure Platelet Transfusion Is Associated With Increased Risk of Thrombosis and Mortality by Schmidt, Amy E, Henrichs, Kelly F, Kirkley, Scott A, Refaai, Majed A, Blumberg, Neil

“…Abstract Objectives We evaluated thrombosis and mortality rates of hospitalized patients receiving prophylactic platelet transfusion prior to an invasive…”
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Total plasma heme concentration increases after red blood cell transfusion and predicts mortality in critically ill medical patients by Pietropaoli, Anthony P., Henrichs, Kelly F., Cholette, Jill M., Spinelli, Sherry L., Phipps, Richard P., Refaai, Majed A., Blumberg, Neil

“…BACKGROUND Relationships between red blood cell (RBC) transfusion, circulating cell‐free heme, and clinical outcomes in critically ill transfusion recipients…”
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Elevated free hemoglobin and decreased haptoglobin levels are associated with adverse clinical outcomes, unfavorable physiologic measures, and altered inflammatory markers in pediatric cardiac surgery patients by Cholette, Jill M., Pietropaoli, Anthony P., Henrichs, Kelly F., Alfieris, George M., Powers, Karen S., Gensini, Francisco, Rubenstein, Jeffrey S., Sweeney, Dawn, Phipps, Richard, Spinelli, Sherry L., Refaai, Majed A., Eaton, Michael P., Blumberg, Neil

“…BACKGROUND There are data suggesting that free hemoglobin (Hb), heme, and iron contribute to infection, thrombosis, multiorgan failure, and death in critically…”
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Washing red blood cells and platelets transfused in cardiac surgery reduces postoperative inflammation and number of transfusions: results of a prospective, randomized, controlled clinical trial by Cholette, Jill M, Henrichs, Kelly F, Alfieris, George M, Powers, Karen S, Phipps, Richard, Spinelli, Sherry L, Swartz, Michael, Gensini, Francisco, Daugherty, L Eugene, Nazarian, Emily, Rubenstein, Jeffrey S, Sweeney, Dawn, Eaton, Michael, Lerner, Norma B, Blumberg, Neil

“…Children undergoing cardiac surgery with cardiopulmonary bypass are susceptible to additional inflammatory and immunogenic insults from blood transfusions. We…”
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Decreased Hemolysis and Improved Platelet Function in Blood Components Washed With Plasma-Lyte A Compared to 0.9% Sodium Chloride by Refaai, Majed A, Conley, Grace W, Henrichs, Kelly F, McRae, Hannah, Schmidt, Amy E, Phipps, Richard P, Spinelli, Sherry L, Masel, Debra, Cholette, Jill M, Pietropaoli, Anthony, Eaton, Michael P, Blumberg, Neil

“…Abstract Objectives Washing cellular blood products is accepted to ameliorate repeated severe allergic reactions but is associated with RBC hemolysis and…”
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Longer RBC storage duration is associated with increased postoperative infections in pediatric cardiac surgery by Cholette, Jill M, Pietropaoli, Anthony P, Henrichs, Kelly F, Alfieris, George M, Powers, Karen S, Phipps, Richard, Spinelli, Sherry L, Swartz, Michael, Gensini, Francisco, Daugherty, L Eugene, Nazarian, Emily, Rubenstein, Jeffrey S, Sweeney, Dawn, Eaton, Michael, Blumberg, Neil

“…Infants and children undergoing open heart surgery routinely require multiple RBC transfusions. Children receiving greater numbers of RBC transfusions have…”
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Oxidation Reduction Potential (ORP) is Predictive of Complications Following Pediatric Cardiac Surgery by Schmidt, Amy E., Gore, Emily, Henrichs, Kelly F., Conley, Grace, Dorsey, Charles, Bjugstad, Kimberly B., Refaai, Majed A., Blumberg, Neil, Cholette, Jill M.

“…Oxidation reduction potential (ORP) or Redox is the ratio of activity between oxidizers and reducers. Oxidative stress (OS) can cause cellular injury and…”
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Transfusion of cell saver salvaged blood in neonates and infants undergoing open heart surgery significantly reduces RBC and coagulant product transfusions and donor exposures: results of a prospective, randomized, clinical trial by Cholette, Jill M, Powers, Karen S, Alfieris, George M, Angona, Ronald, Henrichs, Kelly F, Masel, Debra, Swartz, Michael F, Daugherty, L Eugene, Belmont, Kevin, Blumberg, Neil

“…To evaluate whether transfusion of cell saver salvaged, stored at the bedside for up to 24 hrs, would decrease the number of postoperative allogeneic RBC…”
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Improved outcomes in acute myeloid leukemia patients treated with washed transfusions by Greener, Daniel, Henrichs, Kelly F., Liesveld, Jane L., Heal, Joanna M., Aquina, Christopher T., Phillips, Gordon L., Kirkley, Scott A., Milner, Laurie A., Refaai, Majed A., Mendler, Jason H., Szydlowski, Jill, Masel, Debra, Schmidt, Amy, Boscoe, Francis P., Schymura, Maria J., Blumberg, Neil

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Isoprostane and isofuran lipid mediators accumulate in stored red blood cells and influence platelet function in vitro by Spinelli, Sherry L., Lannan, Katie L., Casey, Ann E., Croasdell, Amanda, Curran, Timothy M., Henrichs, Kelly F., Pollock, Stephen J., Milne, Ginger A., Refaai, Majed A., Francis, Charles W., Phipps, Richard P., Blumberg, Neil

“…Background Stored red blood cells (RBCs) release hemoglobin (Hb) that leads to oxidative damage, which may contribute to thrombosis in susceptible transfusion…”
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Alterations of platelet function and clot formation kinetics after in vitro exposure to anti-A and -B by Refaai, Majed A., Carter, Jessie, Henrichs, Kelly F., Davidson, Donna C., Pollock, Stephen J., Casey, Ann E., Spinelli, Sherry L., Phipps, Richard P., Francis, Charles W., Blumberg, Neil

“…BACKGROUND: ABO‐mismatched platelets (PLTs) are commonly transfused despite reported complications. We hypothesized that because PLTs possess A and B antigens…”
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An association of ABO non-identical platelet and cryoprecipitate transfusions with altered red cell transfusion needs in surgical patients by Refaai, Majed A., Fialkow, Lawrence B., Heal, Joanna M., Henrichs, Kelly F., Spinelli, Sherry L., Phipps, Richard P., Masel, Edward, Smith, Brian H., Corsetti, James P., Francis, Charles W., Bankey, Paul E., Blumberg, Neil

“…Background  Transfusion of ABO non‐identical plasma, platelets and cryoprecipitate is routine practice even though adverse effects can occur. Methods and…”
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Met-Hemoglobin Is a Biomarker for Poor Oxygen Delivery in Infants Following Surgical Palliation by Swartz, Michael F., Makhija, Pooja, Rubenstein, Jeffrey, Henrichs, Kelly F., Powers, Karen S., Wang, Hong Yue, Simon, Bartholomew V., Alfieris, George M., Blumberg, Neil, Cholette, Jill M.

“…Background: Infants with cyanotic congenital heart disease demonstrate wide fluctuations in hemoglobin (Hb), oxygen saturation, and cardiac output following…”
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Platelet Refractoriness Due to Anti-CD-36(NAKa) Ameliorated By Platelet Washing by Sahai, Tanmay, Masel, Debra, Henrichs, Kelly F, Schmidt, Amy E, Refaai, Majed A., Kirkley, Scott A., Mendler, Jason H., Blumberg, Neil

“…▪ Introduction: Platelet transfusion refractoriness in patients with hematological malignancies ranges from 7-34% (Blood 2015; 126:3484). The etiology of…”
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ABO Identical and Washed Transfusions Are Candidate Strategies to Reduce Early Mortality in Acute Promyelocytic Leukemia (APL) by Refaai, Majed A., Henrichs, Kelly F, Heal, Joanna M., Schmidt, Amy E, Mendler, Jason H., Kirkley, Scott A., Aquina, Christopher, Masel, Debra, Liesveld, Jane, Blumberg, Neil

“…▪ Background: Despite dramatically improved long term outcomes seen with all-trans retinoic acid therapy in APL, early mortality remains a substantial…”
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Decreased Hemolysis of Red Cells Washed with Plasma-Lyte As Compared with 0.9% Sodium Chloride by Kirkley, Scott A., Henrichs, Kelly F, Schmidt, Amy P., Refaai, Majed A., Phipps, Richard P., Spinelli, Sherry L, Masel, Debra, Cholette, Jill M, Pietropaoli, Anthony, Heal, Joanna M., Blumberg, Neil

“…Introduction -Washed red blood cell (RBC) and platelet transfusions have been a valuable therapeutic option for patients with repeated or severe allergic or…”
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Isoprostane and isofuran lipid mediators accumulate in stored red blood cell concentrates and influence platelet function in vitro by Spinelli, Sherry L., Lannan, Katie L., Casey, Ann E., Croasdell, Amanda, Curran, Timothy M., Henrichs, Kelly F., Pollock, Stephen J., Milne, Ginger A., Refaai, Majed A., Francis, Charles W., Phipps, Richard P., Blumberg, Neil

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Longer red blood cell storage duration is associated with increased post-operative infections in pediatric cardiac surgery by Cholette, Jill M., Pietropaoli, Anthony P., Henrichs, Kelly F., Alfieris, George M., Powers, Karen S., Phipps, Richard, Spinelli, Sherry L., Swartz, Michael, Gensini, Francisco, Daugherty, L. Eugene, Nazarian, Emily, Rubenstein, Jeffrey S., Sweeney, Dawn, Eaton, Michael, Blumberg, Neil

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