Search Results - "Henri, T."

5‑Aminothiazoles Reveal a New Ligand-Binding Site on Prolyl Oligopeptidase Which is Important for Modulation of Its Protein–Protein Interaction-Derived Functions by Pätsi, Henri T., Kilpeläinen, Tommi P., Jumppanen, Mikael, Uhari-Väänänen, Johanna, Wielendaele, Pieter Van, De Lorenzo, Francesca, Cui, Hengjing, Auno, Samuli, Saharinen, Janne, Seppälä, Erin, Sipari, Nina, Savinainen, Juha, De Meester, Ingrid, Lambeir, Anne-Marie, Lahtela-Kakkonen, Maija, Myöhänen, Timo T., Wallén, Erik A. A.

“…A series of novel 5-aminothiazole-based ligands for prolyl oligopeptidase (PREP) comprise selective, potent modulators of the protein–protein interaction…”
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Nonpeptidic Oxazole-Based Prolyl Oligopeptidase Ligands with Disease-Modifying Effects on α‑Synuclein Mouse Models of Parkinson’s Disease by Kilpeläinen, Tommi P., Pätsi, Henri T., Svarcbahs, Reinis, Julku, Ulrika H., Eteläinen, Tony S., Cui, Hengjing, Auno, Samuli, Sipari, Nina, Norrbacka, Susanna, Leino, Teppo O., Jäntti, Maria, Myöhänen, Timo T., Wallén, Erik A. A.

“…Prolyl oligopeptidase (PREP) is a widely distributed serine protease in the human body cleaving proline-containing peptides; however, recent studies suggest…”
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2‑Imidazole as a Substitute for the Electrophilic Group Gives Highly Potent Prolyl Oligopeptidase Inhibitors by Pätsi, Henri T, Kilpeläinen, Tommi P, Auno, Samuli, Dillemuth, Pyry M. J, Arja, Khaled, Lahtela-Kakkonen, Maija K, Myöhänen, Timo T, Wallén, Erik A. A

“…Different five-membered nitrogen-containing heteroaromatics in the position of the typical electrophilic group in prolyl oligopeptidase (PREP) inhibitors were…”
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A Survey on Technologies Which Make Bitcoin Greener or More Justified by Heinonen, Henri T., Semenov, Alexander, Veijalainen, Jari, Hamalainen, Timo

“…According to recent estimates, one bitcoin transaction consumes as much energy as 1.5 million Visa transactions. Why is bitcoin using so much energy? Most of…”
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Variable residual activity of K-Othrine® PolyZone and Actellic® 300 CS in semi-field and natural conditions in the Democratic Republic of the Congo by Ngwej, Leonard M, Mashat, Emmanuel M, Mukeng, Clarence K, Mundongo, Henri T, Malonga, Françoise K, Kashala, Jean-Christophe K, Bangs, Michael J

“…Background Indoor Residual Spray (IRS) against vector mosquitoes is a primary means for combating malaria transmission. To combat increased patterns of…”
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Impact of Infant Supraglottoplasty on Quality of Life by Vandjelovic, Nathan D., Brown, Jason R., Traboulsi, Henri T., Thottam, Prasad John

“…Objectives The objective of the present study is to examine the impact of supraglottoplasty on the quality of life (QOL) of caregivers and infants with severe…”
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Complement component 3 mutations alter the longitudinal risk of pediatric malaria and severe malarial anemia by Raballah, Evans, Anyona, Samuel B, Cheng, Qiuying, Munde, Elly O, Hurwitz, Ivy-Foo, Onyango, Clinton, Ndege, Caroline, Hengartner, Nicolas W, Pacheco, Maria Andreína, Escalante, Ananias A, Lambert, Christophe G, Ouma, Collins, Obama, Henri C Jr T, Schneider, Kristan A, Seidenberg, Philip D, McMahon, Benjamin H, Perkins, Douglas J

“…Severe malarial anemia (SMA) is a leading cause of childhood morbidity and mortality in holoendemic Plasmodium falciparum transmission regions. To gain…”
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Preparation and physicochemical characterization of a novel water-soluble prodrug of carbamazepine by Hemenway, Jeffrey N, Jarho, Pekka, Henri, John T, Nair, Sajiv K, VanderVelde, David, Georg, Gunda I, Stella, Valentino J

“…N-acyl-urea derivatives of carbamazepine (CBZ) were synthesized through the reactions of iminostilbene with acyl-isocyanates to form N-glycyl-carbamazepine…”
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Urinary hyaluronic acid and hyaluronidase: markers for bladder cancer detection and evaluation of grade by Lokeshwar, V B, Obek, C, Pham, H T, Wei, D, Young, M J, Duncan, R C, Soloway, M S, Block, N L

“…Specific patterns of progression and frequent recurrence of bladder tumors determine the choice of treatment, frequency of surveillance, quality of life, and…”
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Plant natural products: Back to the future or into extinction? by McChesney, James D., Venkataraman, Sylesh K., Henri, John T.

“…Can or will plant derived natural products ever again be the foundation for new drug discovery and development? A scenario is proposed where natural products…”
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Fifth toenail clinical response to systemic antifungal therapy is not a marker of successful therapy for other toenails with onychomycosis by Avner, S, Nir, N, Henri, T

“…Background  Onychodystrophy is a major manifestation of onychomycosis. However, nail trauma may also result in onychodystrophy. The fifth toenail, due to its…”
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Appreciation of localised task lighting in shift work—A field study in the food industry by Juslén, Henri T., Verbossen, Jos, Wouters, Marius C.H.M.

“…Localised task lighting was installed in addition to the general lighting installation in the food factory. Research has been carried out to test appreciation…”
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Association of elevated levels of hyaluronidase, a matrix-degrading enzyme, with prostate cancer progression by LOKESHWAR, V. B, LOKESHWAR, B. L, PHAM, H. T, BLOCK, N. L

“…Components of extracellular matrix and the matrix-degrading enzymes are some of the key regulators of tumor metastasis and angiogenesis. Hyaluronic acid (HA),…”
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Practical syntheses of the C12–C21 epothilone subunit via catalytic asymmetric reductions: Itsuno–Corey oxazaborolidine reduction and asymmetric Noyori hydrogenation by Reiff, Emily A, Nair, Sajiv K, Narayan Reddy, B.S, Inagaki, Jun, Henri, John T, Greiner, Jack F, Georg, Gunda I

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Value Alignment in Online Reviews: A Determinant of Applicant Attitudes and Intentions by Maindidze, Henri T

“…Of interest in this study is the way organizational values communicated in online reviews are recognized and interpreted by job applicants in relation to their…”
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Total Synthesis and Evaluation of C26-Hydroxyepothilone D Derivatives for Photoaffinity Labeling of β-Tubulin by Reiff, Emily A, Nair, Sajiv K, Henri, John T, Greiner, Jack F, Reddy, Bollu S, Chakrasali, Ramappa, David, Sunil A, Chiu, Ting-Lan, Amin, Elizabeth A, Himes, Richard H, Vander Velde, David G, Georg, Gunda I

“…Three photaffinity labeled derivatives of epothilone D were prepared by total synthesis, using efficient novel asymmetric synthesis methods for the preparation…”
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Total synthesis of a potent immunosuppressant pironetin by Gurjar, Mukund K, Henri, John T, Bose, D Subhas, Rao, A V Rama

“…Total synthesis of PA-48153C Pironetin — a potent immunosuppressant is described. Total synthesis of PA-48153C pironetin (1) — a potent immunosuppressant is…”
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Total synthesis and evaluation of C25-benzyloxyepothilone C for tubulin assembly and cytotoxicity against MCF-7 breast cancer cells by Hutt, Oliver E., Reddy, Bollu S., Nair, Sajiv K., Reiff, Emily A., Henri, John T., Greiner, Jack F., Chiu, Ting-Lan, VanderVelde, David G., Amin, Elizabeth A., Himes, Richard H., Georg, Gunda I.

“…The total synthesis of C25-benzyloxy epothilone C is described. A sequential Suzuki–Aldol–Yamaguchi macrolactonization strategy was utilized employing a novel…”
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On Creation of a Stablecoin Based on the Morini's Scheme of Inv&Sav Wallets and Antimoney by Heinonen, Henri T.

“…Decentralized Finance (DeFi) is a popular topic in the blockchain and cryptocurrency industry in the early 2020s. Still, cryptocurrencies have not yet become…”
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Total synthesis and evaluation of 22-(3-azidobenzoyloxy)methyl epothilone C for photoaffinity labeling of β-tubulin by Hutt, Oliver E., Inagaki, Jun, Reddy, Bollu S., Nair, Sajiv K., Reiff, Emily A., Henri, John T., Greiner, Jack F., VanderVelde, David G., Chiu, Ting-Lan, Amin, Elizabeth A., Himes, Richard H., Georg, Gunda I.

“…The total synthesis of 22-(3-azidobenzoyloxy)methyl epothilone C is described as a potential photoaffinity probe to elucidate the β-tubulin binding site. The…”
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