Search Results - "Henning, G"
-
1
Light adaptation controls visual sensitivity by adjusting the speed and gain of the response to light
Published in PloS one (07-08-2019)“…The range of c. 1012 ambient light levels to which we can be exposed massively exceeds the <103 response range of neurons in the visual system, but we can see…”
Get full text
Journal Article -
2
GPx8 peroxidase prevents leakage of H2O2 from the endoplasmic reticulum
Published in Free radical biology & medicine (01-05-2014)“…Unbalanced endoplasmic reticulum (ER) homeostasis (ER stress) leads to increased generation of reactive oxygen species (ROS). Disulfide-bond formation in the…”
Get full text
Journal Article -
3
Electrical control of superconducting spin valves using ferromagnetic helices
Published in Applied physics letters (05-08-2024)“…The geometrical properties of a helical ferromagnet are shown theoretically to control the critical temperature of a proximity-coupled superconductor. Using…”
Get full text
Journal Article -
4
A reinterpretation of critical flicker-frequency (CFF) data reveals key details about light adaptation and normal and abnormal visual processing
Published in Progress in retinal and eye research (01-03-2022)“…Our ability to see flicker has an upper frequency limit above which flicker is invisible, known as the “critical flicker frequency” (CFF), that typically grows…”
Get full text
Journal Article -
5
Diversity-oriented synthesis: producing chemical tools for dissecting biology
Published in Chemical Society reviews (21-06-2012)“…Small molecule modulators of biological function can be discovered by the screening of compound libraries. However, it became apparent that some human disease…”
Get more information
Journal Article -
6
Endoplasmic reticulum: reduced and oxidized glutathione revisited
Published in Journal of cell science (01-04-2013)“…The reducing power of glutathione, expressed by its reduction potential EGSH, is an accepted measure for redox conditions in a given cell compartment. In the…”
Get full text
Journal Article -
7
Transient exposure of a buried phosphorylation site in an autoinhibited protein
Published in Biophysical journal (04-01-2022)“…Autoinhibition is a mechanism used to regulate protein function, often by making functional sites inaccessible through the interaction with a cis-acting…”
Get full text
Journal Article -
8
WHO guideline development of paediatric medicines: Points to consider in pharmaceutical development
Published in International journal of pharmaceutics (05-10-2012)Get full text
Journal Article -
9
Clinical vision and molecular loss: Integrating visual psychophysics with molecular genetics reveals key details of normal and abnormal visual processing
Published in Progress in retinal and eye research (01-07-2021)“…Over the past two decades we have developed techniques and models to investigate the ways in which known molecular defects affect visual performance. Because…”
Get full text
Journal Article -
10
Tidally Heated Terrestrial Exoplanets: Viscoelastic Response Models
Published in The Astrophysical journal (20-12-2009)“…Tidal friction in exoplanet systems, driven by orbits that allow for durable nonzero eccentricities at short heliocentric periods, can generate internal…”
Get full text
Journal Article -
11
Ab initio determination of the shape of membrane proteins in a nanodisc
Published in Acta crystallographica. Section D, Biological crystallography. (01-02-2021)“…New software, called Marbles, is introduced that employs SAXS intensities to predict the shape of membrane proteins embedded into membrane nanodiscs. To gain…”
Get full text
Journal Article -
12
Harmonics added to a flickering light can upset the balance between ON and OFF pathways to produce illusory colors
Published in Proceedings of the National Academy of Sciences - PNAS (24-04-2018)“…The neural signals generated by the light-sensitive photoreceptors in the human eye are substantially processed and recoded in the retina before being…”
Get full text
Journal Article -
13
A Markov chain model for N-linked protein glycosylation – towards a low-parameter tool for model-driven glycoengineering
Published in Metabolic engineering (01-01-2016)“…Glycosylation is a critical quality attribute of most recombinant biotherapeutics. Consequently, drug development requires careful control of glycoforms to…”
Get full text
Journal Article -
14
Preparation of Carbohydrate Arrays by Using Diels-Alder Reactions with Inverse Electron Demand
Published in Chemistry : a European journal (21-05-2012)“…Carbohydrate microarrays are an emerging tool for the high‐throughput screening of carbohydrate–protein interactions that represent the basis of many…”
Get full text
Journal Article -
15
The Pattern of Retinal Ganglion Cell Loss in OPA1-Related Autosomal Dominant Optic Atrophy Inferred From Temporal, Spatial, and Chromatic Sensitivity Losses
Published in Investigative ophthalmology & visual science (01-01-2017)“…Progressive retinal ganglion cell (RGC) loss is the pathological hallmark of autosomal dominant optic atrophy (DOA) caused by pathogenic OPA1 mutations. The…”
Get full text
Journal Article -
16
A strategy for the diversity-oriented synthesis of macrocyclic scaffolds using multidimensional coupling
Published in Nature chemistry (01-10-2013)“…A prerequisite for successful screening campaigns in drug discovery or chemical genetics is the availability of structurally and thus functionally diverse…”
Get full text
Journal Article -
17
Electrical stimulation of the lower esophageal sphincter to address gastroesophageal reflux disease after sleeve gastrectomy
Published in Surgery for obesity and related diseases (01-05-2018)“…Laparoscopic sleeve gastrectomy (LSG) can result in de novo and worsen preexisting gastroesophageal reflux disease (GERD). Post-LSG patients with GERD…”
Get full text
Journal Article -
18
One-Pot Procedure for Diazo Transfer and Azide−Alkyne Cycloaddition: Triazole Linkages from Amines
Published in Organic letters (04-01-2007)“…A one-pot reaction for Cu(II)-catalyzed diazo transfer and Cu(I)-catalyzed azide−alkyne 1,3-dipolar cycloaddition (sometimes called click reaction) is…”
Get full text
Journal Article -
19
Psychophysical measurements in children: challenges, pitfalls, and considerations
Published in PeerJ (San Francisco, CA) (11-05-2017)“…Measuring sensory sensitivity is important in studying development and developmental disorders. However, with children, there is a need to balance reliable but…”
Get full text
Journal Article -
20
Hue shifts produced by temporal asymmetries in chromatic signals depend on the alignment of the first and second harmonics
Published in Journal of vision (Charlottesville, Va.) (01-08-2017)“…When M- or L-cone-isolating sawtooth waveforms flicker at frequencies between 4 and 13.3 Hz, there is a mean hue shift in the direction of the shallower…”
Get full text
Journal Article