Search Results - "Hennig, U. G. G."

Genotype and the cryopreservation process affect the levels of aneuploidy and chromosome breakage in cultured human fibroblasts by Rudd, N L, Hoar, D I, Williams, S E, Hennig, U G

“…Spontaneous micronucleus frequencies were measured in 11 human fibroblast strains, with early-passage cells that had never been frozen and with cells of…”
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Spontaneous mutations and fidelogens by von Borstel, R C, Hennig, U G

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detection of chemical impurities by high pressure liquid chromatography and the genetic activity of medical grades of pyrvinium pamoate in Saccharomyces cerevisiae and Salmonella typhimurium by Hennig, U.G.G, Chatten, L.G, Pon, R.A, Von Borstel, R.C

“…The genetic activity of several medical grades of the anthelmintic drug pyrvinium pamoate, which is a dipyrvinium salt, was studied in a diploid mitotic…”
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Semiaqueous potentiometric determinations of apparent pKa1 values for benzothiadiazines and detection of decomposition during solubility variation with pH studies by Hennig, U G, Moskalyk, R E, Chatten, L G, Chan, S F

“…Apparent acidity constants obtained for various benzothiadiazine diuretics by semiaqueous potentiometric titrations gave satisfactory agreement with many…”
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Kinetochore immunofluorescence in micronuclei: a rapid method for the in situ detection of aneuploidy and chromosome breakage in human fibroblasts by Hennig, U G, Rudd, N L, Hoar, D I

“…We have developed a rapid and simple immunodetection assay for the in situ identification of aneuploidy in mitotic fibroblasts. Kinetochore…”
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Kinetochore analysis of micronuclei allows insights into the actions of colcemid and mitomycin C by Rudd, N L, Williams, S E, Evans, M, Hennig, U G, Hoar, D I

“…We have induced micronuclei in two strains of diploid human fibroblasts with a known aneugen, colcemid, and a known clastogen, mitomycin C. Using…”
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The mutator mut7-1 of Saccharomyces cerevisiae by von Borstel, R C, Ord, R W, Stewart, S P, Ritzel, R G, Lee, G S, Hennig, U G, Savage, E A

“…The mut7-1 mutant of Saccharomyces cerevisiae is a cell-division-cycle mutant, exhibiting temperature-sensitive lethality and enhancement of mutator activity…”
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A comparison of the genetic activity of pyrvinium pamoate with that of several other anthelmintic drugs in Saccharomyces cerevisiae by Hennig, U G, Galindo-Prince, O C, Cortinas de Nava, C, Savage, E A, von Borstel, R C

“…Several anthelmintic drugs that are used routinely in oxyuriasis therapy were analyzed for genotoxicity in a diploid mitotic recombination and gene conversion…”
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A rapid assay for mitochondrial DNA damage and respiratory chain inhibition in the yeast Saccharomyces cerevisiae by Barclay, Barry J., DeHaan, Carrie L., Hennig, Ursula G.G., Iavorovska, Oksana, von Borstel, Reid W., von Borstel, R.C.

“…There is a need for a rapid assay to identify agents that damage mitochondria because the mitochondrion may be an important target for numerous environmental…”
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Topical Reversion at the HIS1 Locus of Saccharomyces cerevisiae {bullet} A Tale of Three Mutants by von Borstel, R. C, Savage, Elizabeth A, Wang, Qi, Hennig, Ursula G. G, Ritzel, R. Gary, Lee, Grace S.-F, Hamilton, Michael D, Chrenek, Micah A, Tomaszewski, Robert W, Higgins, John A, Tenove, Christopher J, Liviero, Lucia, Hastings, Philip J, Korch, Christopher T, Steinberg, C. M

“…Mutants of the HIS1 locus of the yeast Saccharomyces cerevisiae are suitable reporters for spontaneous reversion events because most reversions are topical,…”
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Modification of the kinetochore immunofluorescence staining method for human fibroblasts for use with a commercially available anticentromere antibody by Hennig, U G

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The detection of chemical impurities by high pressure liquid chromatography and the genetic activity of medical grades of pyrvinium pamoate inSaccharomyces cerevisiae andSalmonella typhimurium by Hennig, U. G. G., Chatten, L. G., Pon, R. A., von Borstel, R. C.

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Micronucleus assay in human fibroblasts: a measure of spontaneous chromosomal instability and mutagen hypersensitivity by Rudd, N L, Hoar, D I, Greentree, C L, Dimnik, L S, Hennig, U G

“…By comparing fibroblast strains derived from individuals exhibiting chromosome instability and/or mutagen hypersensitivity (Cockayne syndrome, ataxia…”
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Protection and repair of gamma-radiation-induced lesions in mice with DNA or deoxyribonucleoside treatments by Hennig, U G, Wang, Q, Gee, N H, von Borstel, R C, Henning, U G

“…Mice can survive lethal doses of ionizing radiation if deoxyribonucleosides or 'highly polymerized' salmon sperm DNA (Sigma) are administered 30 min to 24 h…”
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Modulation in cytochrome P-420 and P-450 content in Saccharomyces cerevisiae according to physiological conditions and genetic background by von Borstel, R C, O'Connell, D F, Mehta, R D, Hennig, U G

“…The diploid strain D5 of Saccharomyces cerevisiae, relative to other strains of yeast, has a large amount of cytochrome P-450 present during the logarithmic…”
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Genetic activity in Saccharomyces cerevisiae and thin-layer chromatographic comparisons of medical grades of pyrvinium pamoate and monopyrvinium salts by Mehta, R D, Hennig, U G, von Borstel, R C, Chatten, L G

“…The pamoate, chloride, and iodide salts of pyrvinium, a cyanine dye with anthelmintic properties, were studied in a diploid mitotic recombination and gene…”
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