Search Results - "Hennig, Ewa"
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Polycystic Ovary Syndrome and Oxidative Stress—From Bench to Bedside
Published in International journal of molecular sciences (01-09-2023)“…Oxidative stress (OS) is a condition that occurs as a result of an imbalance between the production of reactive oxygen species (ROS) and the body’s ability to…”
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Genetic Susceptibility to Joint Occurrence of Polycystic Ovary Syndrome and Hashimoto's Thyroiditis: How Far Is Our Understanding?
Published in Frontiers in immunology (26-02-2021)“…Polycystic ovary syndrome (PCOS) and Hashimoto's thyroiditis (HT) are endocrine disorders that commonly occur among young women. A higher prevalence of HT in…”
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3
Helicobacter pylori exploits a unique repertoire of type IV secretion system components for pilus assembly at the bacteria-host cell interface
Published in PLoS pathogens (01-09-2011)“…Colonization of the human stomach by Helicobacter pylori is an important risk factor for development of gastric cancer. The H. pylori cag pathogenicity island…”
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Genes required for assembly of pili associated with the Helicobacter pylori cag type IV secretion system
Published in Infection and immunity (01-08-2014)“…Helicobacter pylori causes numerous alterations in gastric epithelial cells through processes that are dependent on activity of the cag type IV secretion…”
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Exome sequencing to explore the possibility of predicting genetic susceptibility to the joint occurrence of polycystic ovary syndrome and Hashimoto's thyroiditis
Published in Frontiers in immunology (20-07-2023)“…A large body of evidence indicates that women with polycystic ovary syndrome (PCOS) have a higher risk of developing Hashimoto's thyroiditis (HT) than healthy…”
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The N-reductive system composed of mitochondrial amidoxime reducing component (mARC), cytochrome b5 (CYB5B) and cytochrome b5 reductase (CYB5R) is regulated by fasting and high fat diet in mice
Published in PloS one (21-08-2014)“…The mitochondrial amidoxime reducing component mARC is the fourth mammalian molybdenum enzyme. The protein is capable of reducing N-oxygenated structures, but…”
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7
Human Papillomavirus Infections and the Role Played by Cervical and Cervico-Vaginal Microbiota-Evidence from Next-Generation Sequencing Studies
Published in Cancers (01-01-2024)“…This comprehensive review encompasses studies examining changes in the cervical and cervico-vaginal microbiota (CM and CVM) in relation to human papillomavirus…”
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Association of Mitochondrial Variants with the Joint Occurrence of Polycystic Ovary Syndrome and Hashimoto’s Thyroiditis
Published in Antioxidants (01-11-2023)“…Background. The prevalence of Hashimoto’s thyroiditis (HT) among women with polycystic ovary syndrome (PCOS) is higher than in the general female population,…”
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GWAS links variants in neuronal development and actin remodeling related loci with pseudoexfoliation syndrome without glaucoma
Published in Experimental eye research (01-03-2018)“…Pseudoexfoliation syndrome (PEXS) is an age-related elastosis, strongly associated with the development of secondary glaucoma. It is clearly suggested that…”
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10
Comparative kinome analysis to identify putative colon tumor biomarkers
Published in Journal of molecular medicine (Berlin, Germany) (01-04-2012)“…Kinase domains are the type of protein domain most commonly found in genes associated with tumorigenesis. Because of this, the human kinome (the protein kinase…”
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Pooled sample-based GWAS: a cost-effective alternative for identifying colorectal and prostate cancer risk variants in the Polish population
Published in PloS one (19-04-2012)“…Prostate cancer (PCa) and colorectal cancer (CRC) are the most commonly diagnosed cancers and cancer-related causes of death in Poland. To date, numerous…”
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Limited predictive value of achieving beneficial plasma (Z)-endoxifen threshold level by CYP2D6 genotyping in tamoxifen-treated Polish women with breast cancer
Published in BMC cancer (01-08-2015)“…Tamoxifen, the most frequently used drug for treating estrogen receptor-positive breast cancer, must be converted into active metabolites to exert its…”
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13
GWAS Links New Variant in Long Non-Coding RNA LINC02006 with Colorectal Cancer Susceptibility
Published in Biology (Basel, Switzerland) (25-05-2021)“…Despite great efforts, most of the genetic factors contributing to the risk of colorectal cancer (CRC) remain undetermined. Including small but homogenous…”
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14
Common low-penetrance risk variants associated with breast cancer in Polish women
Published in BMC cancer (30-10-2013)“…Breast cancer is the most common type of cancer and the second leading cause of cancer-death among women in Poland. The known high-risk mutations account for…”
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Gene Expression-Based Functional Differences between the Bladder Body and Trigonal Urothelium in Adolescent Female Patients with Micturition Dysfunction
Published in Biomedicines (17-06-2022)“…The aim of this study is to determine the molecular differences between the urothelial transcriptomes of the bladder body and trigone. The transcriptomes of…”
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Mitochondrial-related proteomic changes during obesity and fasting in mice are greater in the liver than skeletal muscles
Published in Functional & integrative genomics (01-03-2014)“…Although mitochondrial dysfunction is implicated in the pathogenesis of obesity, the molecular mechanisms underlying obesity-related metabolic abnormalities…”
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Non- CYP2D6 Variants Selected by a GWAS Improve the Prediction of Impaired Tamoxifen Metabolism in Patients with Breast Cancer
Published in Journal of clinical medicine (24-07-2019)“…A certain minimum plasma concentration of ( )-endoxifen is presumably required for breast cancer patients to benefit from tamoxifen therapy. In this study, we…”
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Extracellular matrix and cytochrome P450 gene expression can distinguish steatohepatitis from steatosis in mice
Published in Journal of cellular and molecular medicine (01-09-2014)“…One of the main questions regarding nonalcoholic fatty liver disease is the molecular background of the transition from simple steatosis (SS) to the…”
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Genetic diversity of 'Candidatus Phytoplasma mali' strains in Poland
Published in Phytopathologia mediterranea (01-01-2015)“…During 2010-2013, samples from 267 apple trees growing in six regions of Poland were tested for phytoplasma presence. 'Candidatus Phytoplasma mali' was…”
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Multiple Chromosomal Loci for the babA Gene in Helicobacter pylori
Published in Infection and Immunity (01-05-2006)“…Helicobacter pylori babA encodes an outer membrane protein that binds to fucosylated Lewis b blood group antigen. We analyzed a panel of 35 H. pylori strains…”
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