Search Results - "Hennessey, Dylan"
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1
Genomic instability in early systemic sclerosis
Published in Journal of autoimmunity (01-07-2022)“…OBJECTIVESSystemic sclerosis (SSc) is associated with secondary malignancies. Previous studies have suggested that mutated cancer proteins, such as RNA…”
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2
Is Cutaneous T-Cell Lymphoma Caused by Ultraviolet Radiation? A Comparison of UV Mutational Signatures in Malignant Melanoma and Mycosis Fungoides
Published in Cells (Basel, Switzerland) (01-06-2023)“…Ultraviolet (UV) radiation is a strong environmental carcinogen responsible for the pathogenesis of most skin cancers, including malignant melanoma (MM) and…”
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3
The Neoantigen Landscape of Mycosis Fungoides
Published in Frontiers in immunology (23-11-2020)“…Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma, for which there is no cure. Immune checkpoint inhibitors have been tried in MF but the…”
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4
Clonotype pattern in T-cell lymphomas map the cell of origin to immature lymphoid precursors
Published in Blood advances (12-04-2022)“…Mature T-cell lymphomas (TCLs) are rare, clinically heterogeneous hematologic cancers with high medical need. TCLs have an inferior prognosis which is…”
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5
Skin colonization by circulating neoplastic clones in cutaneous T-cell lymphoma
Published in Blood (31-10-2019)“…Mycosis fungoides (MF) is a mature T-cell lymphoma currently thought to develop primarily in the skin by a clonal expansion of a transformed, resident memory T…”
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Branched evolution and genomic intratumor heterogeneity in the pathogenesis of cutaneous T-cell lymphoma
Published in Blood advances (09-06-2020)“…Mycosis fungoides (MF) is a slowly progressive cutaneous T-cell lymphoma (CTCL) for which there is no cure. In the early plaque stage, the disease is indolent,…”
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Independent evolution of cutaneous lymphoma subclones in different microenvironments of the skin
Published in Scientific reports (23-09-2020)“…Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma. Lesions of MF are formed by hematogenous seeding the skin with polyclonal (clonotypically…”
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Clonotypic heterogeneity in cutaneous T-cell lymphoma (mycosis fungoides) revealed by comprehensive whole-exome sequencing
Published in Blood advances (09-04-2019)“…Mycosis fungoides (MF), the most common type of cutaneous T-cell lymphoma, is believed to represent a clonal expansion of a transformed skin-resident memory T…”
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