Isolation and enrichment of stem cells

Stem cells have the potential to revolutionize tissue regeneration and engineering. Both general types of stem cells, those with pluripotent differentiation potential as well as those with multipotent differentiation potential, are of equal interest. They are important tools to further understanding...

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Bibliographic Details
Published in:	Advances in biochemical engineering, biotechnology Vol. 114; p. 23
Main Authors:	Bosio, Andreas, Huppert, Volker, Donath, Susan, Hennemann, Petra, Malchow, Michaela, Heinlein, Uwe A O
Format:	Journal Article
Language:	English
Published:	Germany 01-01-2009
Subjects:	Adult Adult Stem Cells - cytology Adult Stem Cells - physiology Cell Differentiation Cells, Cultured Embryonic Stem Cells - cytology Embryonic Stem Cells - physiology Flow Cytometry Guided Tissue Regeneration Hematopoietic Stem Cell Transplantation Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - physiology Humans Immunomagnetic Separation - methods Multipotent Stem Cells - cytology Multipotent Stem Cells - physiology Tissue Engineering Transplantation, Homologous
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Summary:	Stem cells have the potential to revolutionize tissue regeneration and engineering. Both general types of stem cells, those with pluripotent differentiation potential as well as those with multipotent differentiation potential, are of equal interest. They are important tools to further understanding of general cellular processes, to refine industrial applications for drug target discovery and predictive toxicology, and to gain more insights into their potential for tissue regeneration. This chapter provides an overview of existing sorting technologies and protocols, outlines the phenotypic characteristics of a number of different stem cells, and summarizes their potential clinical applications.
ISSN:	0724-6145
DOI:	10.1007/10_2008_38