Search Results - "Henneberry, Annette"

The major sites of cellular phospholipid synthesis and molecular determinants of Fatty Acid and lipid head group specificity by Henneberry, Annette L, Wright, Marcia M, McMaster, Christopher R

“…Phosphatidylcholine and phosphatidylethanolamine are the two main phospholipids in eukaryotic cells comprising ~50 and 25% of phospholipid mass, respectively…”
Get full text

Loss of Subcellular Lipid Transport Due to ARV1 Deficiency Disrupts Organelle Homeostasis and Activates the Unfolded Protein Response by Shechtman, Caryn F., Henneberry, Annette L., Seimon, Tracie A., Tinkelenberg, Arthur H., Wilcox, Lisa J., Lee, Eunjee, Fazlollahi, Mina, Munkacsi, Andrew B., Bussemaker, Harmen J., Tabas, Ira, Sturley, Stephen L.

“…The ARV1-encoded protein mediates sterol transport from the endoplasmic reticulum (ER) to the plasma membrane. Yeast ARV1 mutants accumulate multiple lipids in…”
Get full text

Identification of two novel human acyl-CoA wax alcohol acyltransferases: members of the diacylglycerol acyltransferase 2 (DGAT2) gene superfamily by Turkish, Aaron R, Henneberry, Annette L, Cromley, Debra, Padamsee, Mahajabeen, Oelkers, Peter, Bazzi, Hisham, Christiano, Angela M, Billheimer, Jeffrey T, Sturley, Stephen L

“…The esterification of alcohols such as sterols, diacylglycerols, and monoacylglycerols with fatty acids represents the formation of both storage and…”
Get full text

A Functional, Genome-wide Evaluation of Liposensitive Yeast Identifies the “RE2 Required for Viability” (ARV1) Gene Product as a Major Component of Eukaryotic Fatty Acid Resistance by Ruggles, Kelly V., Garbarino, Jeanne, Liu, Ying, Moon, James, Schneider, Kerry, Henneberry, Annette, Billheimer, Jeff, Millar, John S., Marchadier, Dawn, Valasek, Mark A., Joblin-Mills, Aidan, Gulati, Sonia, Munkacsi, Andrew B., Repa, Joyce J., Rader, Dan, Sturley, Stephen L.

Get full text

Sterol homeostasis in the budding yeast, Saccharomyces cerevisiae by Henneberry, Annette L., Sturley, Stephen L.

“…Lipid related diseases, such as obesity, type 2 diabetes, and atherosclerosis are epidemics in developed civilizations. A common underlying factor among these…”
Get full text

Phosphatidylcholine synthesis influences the diacylglycerol homeostasis required for SEC14p-dependent Golgi function and cell growth by Henneberry, A L, Lagace, T A, Ridgway, N D, McMaster, C R

“…Phosphatidylcholine and phosphatidylethanolamine are the most abundant phospholipids in eukaryotic cells and thus have major roles in the formation and…”
Get full text

Cloning and expression of a human choline/ethanolaminephosphotransferase: synthesis of phosphatidylcholine and phosphatidylethanolamine by Henneberry, A L, McMaster, C R

“…Cholinephosphotransferase catalyses the final step in the synthesis of phosphatidylcholine (PtdCho) via the Kennedy pathway by the transfer of phosphocholine…”
Get full text

Cloning, Genomic Organization, and Characterization of a Human Cholinephosphotransferase by Henneberry, Annette L., Wistow, Graeme, McMaster, Christopher R.

“…A cholinephosphotransferase activity catalyzes the final step in the de novo synthesis of phosphatidylcholine via the transfer of a phosphocholine moiety from…”
Get full text

Uncoupling Farnesol-induced Apoptosis from Its Inhibition of Phosphatidylcholine Synthesis by Wright, M M, Henneberry, A L, Lagace, T A, Ridgway, N D, McMaster, C R

“…Genetic inactivation of the synthesis of phosphatidylcholine, the most abundant membrane lipid in eukaryotic cells, induces apoptosis. Administration of…”
Get full text

Identification of Two Novel Human Acyl-CoA Wax Alcohol Acyltransferases by Turkish, Aaron R., Henneberry, Annette L., Cromley, Debra, Padamsee, Mahajabeen, Oelkers, Peter, Bazzi, Hisham, Christiano, Angela M., Billheimer, Jeffrey T., Sturley, Stephen L.

“…The esterification of alcohols such as sterols, diacylglycerols, and monoacylglycerols with fatty acids represents the formation of both storage and…”
Get full text

A functional, genome-wide evaluation of liposensitive yeast identifies the "ARE2 required for viability" (ARV1) gene product as a major component of eukaryotic fatty acid resistance by Ruggles, Kelly V, Garbarino, Jeanne, Liu, Ying, Moon, James, Schneider, Kerry, Henneberry, Annette, Billheimer, Jeff, Millar, John S, Marchadier, Dawn, Valasek, Mark A, Joblin-Mills, Aidan, Gulati, Sonia, Munkacsi, Andrew B, Repa, Joyce J, Rader, Dan, Sturley, Stephen L

“…The toxic subcellular accumulation of lipids predisposes several human metabolic syndromes, including obesity, type 2 diabetes, and some forms of…”
Get full text

Cloning and expression of a human choline/ethanolaminephosphotransferase: synthesis of phosphatidylcholine and phosphatidylethanolamine by HENNEBERRY, Annette L., McMASTER, Christopher R.

“…Cholinephosphotransferase catalyses the final step in the synthesis of phosphatidylcholine (PtdCho) via the Kennedy pathway by the transfer of phosphocholine…”
Get full text

A Functional, Genome-wide Evaluation of Liposensitive Yeast Identifies the “ARE2Required for Viability” (ARV1) Gene Product as a Major Component of Eukaryotic Fatty Acid Resistance by Ruggles, Kelly V., Garbarino, Jeanne, Liu, Ying, Moon, James, Schneider, Kerry, Henneberry, Annette, Billheimer, Jeff, Millar, John S., Marchadier, Dawn, Valasek, Mark A., Joblin-Mills, Aidan, Gulati, Sonia, Munkacsi, Andrew B., Repa, Joyce J., Rader, Dan, Sturley, Stephen L.

“…The toxic subcellular accumulation of lipids predisposes several human metabolic syndromes, including obesity, type 2 diabetes, and some forms of…”
Get full text

The Role of Arv1 in Sterol Metabolism and its Contribution to the Unfolded Protein Response by Shechtman, Caryn Faith, Henneberry, Annette, Seimon, Tracie, Tabas, Ira, Sturley, Stephen L

“…Proper sterol distribution within the cell is a critical component of membrane homeostasis. The endoplasmic reticulum (ER)‐localized protein Arvl mediates…”
Get full text