Search Results - "Henn, Arnon"
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Myo19 is an outer mitochondrial membrane motor and effector of starvation-induced filopodia
Published in Journal of cell science (01-02-2016)“…Mitochondria respond to environmental cues and stress conditions. Additionally, the disruption of the mitochondrial network dynamics and its distribution is…”
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2
Auxiliary ATP binding sites support DNA unwinding by RecBCD
Published in Nature communications (04-04-2022)“…The RecBCD helicase initiates double-stranded break repair in bacteria by processively unwinding DNA with a rate approaching ∼1,600 bp·s −1 , but the mechanism…”
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3
ROS induced distribution of mitochondria to filopodia by Myo19 depends on a class specific tryptophan in the motor domain
Published in Scientific reports (14-09-2017)“…The role of the actin cytoskeleton in relation to mitochondria function and dynamics is only recently beginning to be recognized. Myo19 is an actin-based motor…”
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4
Synergy between RecBCD subunits is essential for efficient DNA unwinding
Published in eLife (02-01-2019)“…The subunits of the bacterial RecBCD act in coordination, rapidly and processively unwinding DNA at the site of a double strand break. RecBCD is able to…”
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Cofilin-Linked Changes in Actin Filament Flexibility Promote Severing
Published in Biophysical journal (06-07-2011)“…The actin regulatory protein, cofilin, increases the bending and twisting elasticity of actin filaments and severs them. It has been proposed that filaments…”
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6
Pathway of ATP utilization and duplex rRNA unwinding by the DEAD-box helicase, DbpA
Published in Proceedings of the National Academy of Sciences - PNAS (02-03-2010)“…DEAD-box RNA helicase proteins use the energy of ATP hydrolysis to drive the unwinding of duplex RNA. However, the mechanism that couples ATP utilization to…”
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The Conserved Lysine-265 Allosterically Modulates Nucleotide- and Actin-binding Site Coupling in Myosin-2
Published in Scientific reports (09-08-2017)“…Myosin motor proteins convert chemical energy into force and movement through their interactions with nucleotide and filamentous actin (F-actin). The…”
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Myosin Isoform Determines the Conformational Dynamics and Cooperativity of Actin Filaments in the Strongly Bound Actomyosin Complex
Published in Journal of molecular biology (26-02-2010)“…We used transient phosphorescence anisotropy to detect the microsecond rotational dynamics of erythrosin-iodoacetamide-labeled actin strongly bound to…”
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9
Vertebrate Myosin VIIb Is a High Duty Ratio Motor Adapted for Generating and Maintaining Tension
Published in The Journal of biological chemistry (25-11-2005)“…Kinetic adaptation of muscle and non-muscle myosins plays a central role in defining the unique cellular functions of these molecular motor enzymes. The…”
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10
Thermodynamics of Nucleotide Binding to Actomyosin V and VI: A Positive Heat Capacity Change Accompanies Strong ADP Binding
Published in Biochemistry (Easton) (02-08-2005)“…We have measured the energetics of ATP and ADP binding to single-headed actomyosin V and VI from the temperature dependence of the rate and equilibrium binding…”
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The unique enzymatic and mechanistic properties of plant myosins
Published in Current opinion in plant biology (01-12-2014)“…•Plant myosins have acquired unique and specific enzymatic adaptations and cellular functions.•Myosin VIII has been characterized as a slow actin-based…”
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12
Visualization of Unwinding Activity of Duplex RNA by DbpA, a DEAD Box Helicase, at Single-Molecule Resolution by Atomic Force Microscopy
Published in Proceedings of the National Academy of Sciences - PNAS (24-04-2001)“…The Escherichia coli protein DbpA is unique in its subclass of DEAD box RNA helicases, because it possesses ATPase-specific activity toward the peptidyl…”
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13
Interdependent Nutrient Availability and Steroid Hormone Signals Facilitate Root Growth Plasticity
Published in Developmental cell (02-07-2018)“…Plants acquire essential elements from inherently heterogeneous soils, in which phosphate and iron availabilities vary. Consequently, plants have developed…”
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14
Kinetic adaptation of human Myo19 for active mitochondrial transport to growing filopodia tips
Published in Scientific reports (14-09-2017)“…Myosins are actin-based molecular motors which are enzymatically adapted for their cellular functions such as transportation and membrane tethering. Human…”
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15
Communication between DNA and nucleotide binding sites facilitates stepping by the RecBCD helicase
Published in Nucleic acids research (24-04-2024)“…Double-strand DNA breaks are the severest type of genomic damage, requiring rapid response to ensure survival. RecBCD helicase in prokaryotes initiates…”
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Nucleotides Linkage Analysis of RecBCD DNA Helicase
Published in Biophysical journal (27-01-2015)Get full text
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17
An i-motif-regulated enhancer, eRNA and adjacent lncRNA affect Lhb expression through distinct mechanisms in a sex-specific context
Published in Cellular and molecular life sciences : CMLS (19-08-2024)“…Genome-wide studies have demonstrated regulatory roles for diverse non-coding elements, but their precise and interrelated functions have often remained…”
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The RNA Helicase DbpA Exhibits a Markedly Different Conformation in the ADP-bound State When Compared with the ATP- or RNA-Bound States
Published in The Journal of biological chemistry (29-11-2002)“…The motor enzymes that belong to the family of RNA helicases catalyze the strand separation of duplex RNA via ATP hydrolysis. Among these enzymes, Escherichia…”
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Characterzing the Auxiliary Nucleotide Binding Sites in RecBCD DNA Helicase, Towards Deciphering their Functional Role
Published in Biophysical journal (07-02-2020)Get full text
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20
Investigating the Role of the Auxiliary Nucleotide Binding Sites in the Recbcd DNA Helicase
Published in Biophysical journal (15-02-2019)Get full text
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