Search Results - "Henley, Beverley M."
-
1
Chronobiology of Parkinson's disease: Past, present and future
Published in The European journal of neuroscience (01-01-2023)“…Parkinson's disease is a neurodegenerative disorder predominately affecting midbrain dopaminergic neurons that results in a broad range of motor and non‐motor…”
Get full text
Journal Article -
2
Incubator embedded cell culture imaging system (EmSight) based on Fourier ptychographic microscopy
Published in Biomedical optics express (01-08-2016)“…Multi-day tracking of cells in culture systems can provide valuable information in bioscience experiments. We report the development of a cell culture imaging…”
Get full text
Journal Article -
3
Deletion of lynx1 reduces the function of α6 nicotinic receptors
Published in PloS one (01-12-2017)“…The α6 nicotinic acetylcholine receptor (nAChR) subunit is an attractive drug target for treating nicotine addiction because it is present at limited sites in…”
Get full text
Journal Article -
4
Menthol Enhances Nicotine Reward-Related Behavior by Potentiating Nicotine-Induced Changes in nAChR Function, nAChR Upregulation, and DA Neuron Excitability
Published in Neuropsychopharmacology (New York, N.Y.) (01-11-2017)“…Understanding why the quit rate among smokers of menthol cigarettes is lower than non-menthol smokers requires identifying the neurons that are altered by…”
Get full text
Journal Article -
5
Menthol Alone Upregulates Midbrain nAChRs, Alters nAChR Subtype Stoichiometry, Alters Dopamine Neuron Firing Frequency, and Prevents Nicotine Reward
Published in The Journal of neuroscience (09-03-2016)“…Upregulation of β2 subunit-containing (β2*) nicotinic acetylcholine receptors (nAChRs) is implicated in several aspects of nicotine addiction, and menthol…”
Get full text
Journal Article -
6
Smoking-Relevant Nicotine Concentration Attenuates the Unfolded Protein Response in Dopaminergic Neurons
Published in The Journal of neuroscience (06-01-2016)“…Retrospective epidemiological studies show an inverse correlation between susceptibility to Parkinson's disease and a person's history of tobacco use. Animal…”
Get full text
Journal Article -
7
Transcriptional regulation by nicotine in dopaminergic neurons
Published in Biochemical pharmacology (15-10-2013)“…Dopaminergic neurons in the substantia nigra pars compacta (SNc) degenerate in Parkinson's disease. These neurons robustly express several nicotinic…”
Get full text
Journal Article -
8
Reliable Identification of Living Dopaminergic Neurons in Midbrain Cultures Using RNA Sequencing and TH-promoter-driven eGFP Expression
Published in Journal of visualized experiments (10-02-2017)“…In Parkinson's Disease (PD) there is widespread neuronal loss throughout the brain with pronounced degeneration of dopaminergic neurons in the SNc, leading to…”
Get full text
Journal Article -
9
The Expression of Neuroepithelial Cell Fate Determinants in Rat Spinal Cord Development
Published in Journal of molecular neuroscience (01-09-2010)“…Lineage specification is tightly regulated by a unique combination of extrinsic and intrinsic cues, but exactly how these cues coordinate the timing and…”
Get full text
Journal Article -
10
Deletion of lynx1 reduces the function of [alpha]6 nicotinic receptors
Published in PloS one (05-12-2017)“…The [alpha]6 nicotinic acetylcholine receptor (nAChR) subunit is an attractive drug target for treating nicotine addiction because it is present at limited…”
Get full text
Journal Article -
11