Search Results - "Henklein, P."

Proteasomes generate spliced epitopes by two different mechanisms and as efficiently as non-spliced epitopes by Ebstein, F., Textoris-Taube, K., Keller, C., Golnik, R., Vigneron, N., Van den Eynde, B. J., Schuler-Thurner, B., Schadendorf, D., Lorenz, F. K. M., Uckert, W., Urban, S., Lehmann, A., Albrecht-Koepke, N., Janek, K., Henklein, P., Niewienda, A., Kloetzel, P. M., Mishto, M.

“…Proteasome-catalyzed peptide splicing represents an additional catalytic activity of proteasomes contributing to the pool of MHC-class I-presented epitopes. We…”
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Therapeutic potential of larval excretory/secretory proteins of the pig whipworm Trichuris suis in allergic disease by Ebner, F., Hepworth, M. R., Rausch, S., Janek, K., Niewienda, A., Kühl, A., Henklein, P., Lucius, R., Hamelmann, E., Hartmann, S.

“…Background Gastrointestinal nematodes are currently being evaluated as a novel therapeutic in the treatment of chronic human inflammatory disorders, due to…”
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Changes in spatio-temporal localization of tripeptidyl peptidase II (TPPII) in murine colon adenocarcinoma cells during aggresome formation: a microscopy study based on a novel fluorescent proteasome inhibitor by Bialy, L P, Kuckelkorn, U, Henklein, P, Fayet, J, Wilczyński, G M, Kamiński, A, Mlynarczuk-Bialy, I

“…Extralysosomal proteolysis is a multistep process involving the Ubiquitin- Proteasome System (UPS) and supplementary peptidases. Tripeptidyl peptidase II…”
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PB1-F2, an Influenza A Virus-Encoded Proapoptotic Mitochondrial Protein, Creates Variably Sized Pores in Planar Lipid Membranes by CHANTURIYA, A. N, BASANEZ, G, SCHUBERT, U, HENKLEIN, P, YEWDELL, J. W, ZIMMERBERG, J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A 41 amino acid motif in importin‐alpha confers binding to importin‐beta and hence transit into the nucleus by Görlich, D., Henklein, P., Laskey, R. A., Hartmann, E.

“…The complex of importin‐alpha and ‐beta is essential for nuclear protein import. It binds the import substrate in the cytosol, and the resulting trimeric…”
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Synthesis, Characterization, and Biological Properties of Cyanine-Labeled Somatostatin Analogues as Receptor-Targeted Fluorescent Probes by Licha, Kai, Hessenius, Carsten, Becker, Andreas, Henklein, Peter, Bauer, Michael, Wisniewski, Stefan, Wiedenmann, Bertram, Semmler, Wolfhard

“…We present the synthesis and characterization of the somatostatin receptor-specific peptide H2N-(d-Phe)-cyclo[Cys-Phe-(d-Trp)-Lys-Thr-Cys]-Thr-OH, which is…”
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Analysis of mammalian 20S proteasome biogenesis: the maturation of beta‐subunits is an ordered two‐step mechanism involving autocatalysis by Schmidtke, G., Kraft, R., Kostka, S., Henklein, P., Frömmel, C., Löwe, J., Huber, R., Kloetzel, P. M., Schmidt, M.

“…Maturation of eukaryotic 20S proteasomes involves the processing of beta‐subunits by limited proteolysis. To study the processing mechanism we analysed…”
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Identification of HLA-B27-Restricted Peptides from the Chlamydia trachomatis Proteome with Possible Relevance to HLA-B27-Associated Diseases by Kuon, Wolfgang, Holzhutter, Hermann-Georg, Appel, Heiner, Grolms, Martina, Kollnberger, Simon, Traeder, Alexander, Henklein, Peter, Weiss, Elisabeth, Thiel, Andreas, Lauster, Roland, Bowness, Paul, Radbruch, Andreas, Kloetzel, Peter-Michael, Sieper, Joachim

“…The association of HLA-B27 with ankylosing spondylitis and reactive arthritis is the strongest one known between an MHC class I Ag and a disease. We have…”
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The Solid State and Solution Structure of HAPyU by Carpino, Louis A, Henklein, Peter, Foxman, Bruce M, Abdelmoty, Iman, Costisella, Burkhard, Wray, Victor, Domke, Tobias, El-Faham, Ayman, Mügge, C

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PAR-1- and PAR-3-type thrombin receptor expression in primary cultures of human renal cell carcinoma cells by Kaufmann, R, Junker, U, Nuske, K, Westermann, M, Henklein, P, Scheele, J, Junker, K

“…In this study, we report coexpression of proteinase-activated receptor (PAR)-1- and PAR-3-type thrombin receptors in primary cultures obtained from surgically…”
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The two-receptor system PAR-1/PAR-4 mediates alpha-thrombin-induced [Ca(2+)](i) mobilization in human astrocytoma cells by Kaufmann, R, Patt, S, Zieger, M, Kraft, R, Tausch, S, Henklein, P, Nowak, G

“…The proteinase-activated receptor 1 (PAR-1) was characterized as a functional receptor for thrombin in cells from different brain tumor entities. Whether PAR-1…”
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Addition of HOAt dramatically improves the effectiveness of pentafluorophenyl-based coupling reagents by Klose, J., El-Faham, A., Henklein, P., Carpino, L.A., Bienert, M.

“…In the course of comparing the effectiveness of several HOAt- and HOPfp-derived coupling reagents by cyclization and segment condensation of model sequences,…”
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Plasma and urine salsolinol in humans: effect of acute ethanol intake on the enantiomeric composition of salsolinol by Haber, H, Winkler, A, Putscher, I, Henklein, P, Baeger, I, Georgi, M, Melzig, M F

“…The tetrahydroisoquinoline (TIQ) salsolinol (SAL), a condensation product of dopamine and pyruvate or acetaldehyde, is one of the neuropharmacologically active…”
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Different signaling pathways are involved in CCK(B) receptor-mediated MAP kinase activation in COS-7 cells by Zieger, M, Oehrl, W, Wetzker, R, Henklein, P, Nowak, G, Kaufmann, R

“…Recently, the involvement of the MAP kinase ERK in mitogenic signaling of cholecystokininB (CCK(B)) receptors has been shown. However, the intracellular…”
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Replacement of fetal calf serum in cell cultures by an egg yolk factor with cholecystokinin/gastrin-like immunoreactivity by SASSE, Mirko, LENGWINAT, Thomas, HENKLEIN, Peter, HLINAK, Andreas, SCHADE, Rüdiger

“…The in vitro culture of various cell types is an important scientific tool and is becoming increasingly acceptable as a viable alternative to animal…”
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A novel influenza A virus mitochondrial protein that induces cell death by Yewdell, Jonathan W, Chen, Weisan, Calvo, Paul A, Malide, Daniela, Gibbs, James, Schubert, Ulrich, Bacik, Igor, Basta, Sameh, O'Neill, Robert, Schickli, Jeanne, Palese, Peter, Henklein, Peter, Bennink, Jack R

“…While searching for alternative reading-frame peptides encoded by influenza A virus that are recognized by CD8+ T cells, we found an abundant immunogenic…”
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Signaling effects of α-thrombin and SFLLRN in rat glioma C6 cells by Kaufmann, R., Lindschau, C., Höer, A., Henklein, P., Adomeit, A., Haller, H., Liebmann, C., Oberdisse, E., Nowak, G.

“…Effects of thrombin on brain cells, including change of neurite outgrowth and astrocyte shape, are described, but the molecular mechanisms are unclear. We…”
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Cholecystokinin B-type receptor signaling is involved in human pancreatic cancer cell growth by Kaufmann, R, Schafberg, H, Rudroff, C, Henklein, P, Nowak, G

“…Cholecystokinin (CCK) is known to stimulate pancreatic cancer cell growth, but no detailed CCK receptor subtype characterization and investigation of CCK…”
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The two-receptor system PAR-1/PAR-4 mediates α-thrombin-induced [Ca2+]i mobilization in human astrocytoma cells by KAUFMANN, R, PATT, S, ZIEGER, M, KRAFT, R, TAUSCH, S, HENKLEIN, P, NOWAK, G

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Effects of two newly synthetized cholecystokinin tetrapeptides on the activity of single hippocampal and thalamic neurons by Zippel, U, Henklein, P

“…The influence of two iontophoretically administered newly developed cholecystokinin (CCK) tetrapeptides with high selectivity and affinity to CCK-B receptors…”
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