Search Results - "Henkelman, M M"

Zebrafish models of idiopathic scoliosis link cerebrospinal fluid flow defects to spine curvature by Grimes, D. T., Boswell, C. W., Morante, N. F. C., Henkelman, R. M., Burdine, R. D., Ciruna, B.

“…Idiopathic scoliosis (IS) affects 3% of children worldwide, yet the mechanisms underlying this spinal deformity remain unknown. Here we show that ptk7 mutant…”
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Magnetization transfer in MRI: a review by Henkelman, R. M., Stanisz, G. J., Graham, S. J.

“…This review describes magnetization transfer (MT) contrast in magnetic resonance imaging. A qualitative description of how MT works is provided along with…”
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High resolution three-dimensional brain atlas using an average magnetic resonance image of 40 adult C57Bl/6J mice by Dorr, A.E., Lerch, J.P., Spring, S., Kabani, N., Henkelman, R.M.

“…Detailed anatomical atlases can provide considerable interpretive power in studies of both human and rodent neuroanatomy. Here we describe a three-dimensional…”
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Neuroanatomical phenotypes in a mouse model of the 22q11.2 microdeletion by Ellegood, J, Markx, S, Lerch, J P, Steadman, P E, Genç, C, Provenzano, F, Kushner, S A, Henkelman, R M, Karayiorgou, M, Gogos, J A

“…Recurrent deletions at the 22q11.2 locus have been established as a strong genetic risk factor for the development of schizophrenia and cognitive dysfunction…”
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The Ubiquitin Ligase Nedd4-1 Is Required for Heart Development and Is a Suppressor of Thrombospondin-1 by Fouladkou, Fatemeh, Lu, Chen, Jiang, Chong, Zhou, Limei, She, Yimin, Walls, Jonathon R., Kawabe, Hiroshi, Brose, Nils, Henkelman, R.M., Huang, Annie, Bruneau, Benoit G., Rotin, Daniela

“…Nedd4 (Nedd4-1) is a Hect domain E3 ubiquitin ligase that also contains a C2 domain and three WW domains. Despite numerous in vitro studies, its biological…”
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Emotional social support and job burnout among high-school teachers: is it all due to dispositional affectivity? by Kahn, Jeffrey H., Schneider, Kimberly T., Jenkins-Henkelman, Theresa M., Moyle, Laura L.

“…The authors investigated whether the relationship between the contents of emotional social support and job burnout among high-school teachers is spurious…”
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A Three-dimensional MRI Atlas of the Mouse Brain with Estimates of the Average and Variability by Kovačević, N., Henderson, J.T., Chan, E., Lifshitz, N., Bishop, J., Evans, A.C., Henkelman, R.M., Chen, X.J.

“…Although there is growing interest in finding mouse models of human disease, no technique for quickly and quantitatively determining anatomical mutants…”
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Mouse embryonic phenotyping by morphometric analysis of MR images by Zamyadi, M, Baghdadi, L, Lerch, J P, Bhattacharya, S, Schneider, J E, Henkelman, R M, Sled, J G

“…A new method is described for automatic detection of subtle morphological phenotypes in mouse embryos. Based on high-resolution magnetic resonance imaging…”
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Age-dependent endothelial nitric oxide synthase uncoupling in pulmonary arteries of endoglin heterozygous mice by Belik, J, Jerkic, M, McIntyre, B A S, Pan, J, Leen, J, Yu, L X, Henkelman, R M, Toporsian, M, Letarte, M

“…Endoglin is a TGF-beta superfamily receptor critical for endothelial cell function. Mutations in this gene are associated with hereditary hemorrhagic…”
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Altered palmitoylation and neuropathological deficits in mice lacking HIP14 by Singaraja, Roshni R., Huang, Kun, Sanders, Shaun S., Milnerwood, Austen J., Hines, Rochelle, Lerch, Jason P., Franciosi, Sonia, Drisdel, Renaldo C., Vaid, Kuljeet, Young, Fiona B., Doty, Crystal, Wan, Junmei, Bissada, Nagat, Henkelman, R. Mark, Green, William N., Davis, Nicholas G., Raymond, Lynn A., Hayden, Michael R.

“…Huntingtin interacting protein 14 (HIP14, ZDHHC17) is a huntingtin (HTT) interacting protein with palmitoyl transferase activity. In order to interrogate the…”
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062 C-type natriuretic peptide is involved in proteoglycan-rich leaflet thickening in early aortic valve disease by Blaser, M.C, Sider, K.L, Zhou, Y, Henkelman, M, Simmons, C.A

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Ex vivo tissue-type independence in proton-resonance frequency shift MR thermometry by Peters, R D, Hinks, R S, Henkelman, R M

“…The temperature sensitivity of the proton-resonance frequency (PRF) has proven valuable for the monitoring of MR image-guided thermal coagulation therapy…”
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Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity by Ellegood, J, Anagnostou, E, Babineau, B A, Crawley, J N, Lin, L, Genestine, M, DiCicco-Bloom, E, Lai, J K Y, Foster, J A, Peñagarikano, O, Geschwind, D H, Pacey, L K, Hampson, D R, Laliberté, C L, Mills, A A, Tam, E, Osborne, L R, Kouser, M, Espinosa-Becerra, F, Xuan, Z, Powell, C M, Raznahan, A, Robins, D M, Nakai, N, Nakatani, J, Takumi, T, van Eede, M C, Kerr, T M, Muller, C, Blakely, R D, Veenstra-VanderWeele, J, Henkelman, R M, Lerch, J P

“…Autism is a heritable disorder, with over 250 associated genes identified to date, yet no single gene accounts for >1–2% of cases. The clinical presentation,…”
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An analytical model of restricted diffusion in bovine optic nerve by Stanisz, G J, Szafer, A, Wright, G A, Henkelman, R M

“…An analytical model of restricted diffusion in bovine optic nerve is presented. The nerve tissue model is composed of two different objects: prolate ellipsoids…”
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Relaxivity and magnetization transfer of white matter lipids at MR imaging: importance of cerebrosides and pH by Kucharczyk, W, Macdonald, P M, Stanisz, G J, Henkelman, R M

“…To measure the effect of the major lipid components of white matter on the relaxation times and magnetization transfer (MT) of water protons. Multilamellar…”
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Analysis of changes in MR properties of tissues after heat treatment by Graham, S.J., Stanisz, G.J., Kecojevic, A., Bronskill, M.J., Henkelman, R.M.

“…To characterize changes in the MR parameters of tissues due to thermal coagulation, a series of T1, T2, diffusion, and magnetization transfer measurements were…”
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Branching tree model with fractal vascular resistance explains fractal perfusion heterogeneity by Marxen, M, Henkelman, R M

“…Perfusion heterogeneities in organs such as the heart obey a power law as a function of scale, a behavior termed "fractal." An explanation of why vascular…”
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Delayed myelination in a mouse model of fragile X syndrome by Pacey, L. K. K., Xuan, I. C. Y., Guan, S., Sussman, D., Henkelman, R. M., Chen, Y., Thomsen, C., Hampson, D. R.

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Kctd13-deficient mice display short-term memory impairment and sex-dependent genetic interactions by Arbogast, Thomas, Razaz, Parisa, Ellegood, Jacob, McKinstry, Spencer U, Erdin, Serkan, Currall, Benjamin, Aneichyk, Tanya, Lerch, Jason P, Qiu, Lily R, Rodriguiz, Ramona M, Henkelman, R M, Talkowski, Michael E, Wetsel, William C, Golzio, Christelle, Katsanis, Nicholas

“…Abstract The 16p11.2 BP4-BP5 deletion and duplication syndromes are associated with a complex spectrum of neurodevelopmental phenotypes that includes…”
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3D visualization of the regional differences by Ellegood, J, Anagnostou, E, Babineau, B A, Crawley, J N, Lin, L, Genestine, M, DiCicco-Bloom, E, Lai, J K Y, Foster, J A, Peñagarikano, O, Geschwind, D H, Pacey, L K, Hampson, D R, Laliberté, C L, Mills, A A, Tam, E, Osborne, L R, Kouser, M, Espinosa-Becerra, F, Xuan, Z, Powell, C M, Raznahan, A, Robins, D M, Nakai, N, Nakatani, J, Takumi, T, van Eede, M C, Kerr, T M, Muller, C, Blakely, R D, Veenstra-VanderWeele, J, Henkelman, R M, Lerch, J P

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