Search Results - "Henkel, D."

Similarities and dissimilarities between psychiatric cluster disorders by Smail, Marissa A., Wu, Xiaojun, Henkel, Nicholas D., Eby, Hunter M., Herman, James P., McCullumsmith, Robert E., Shukla, Rammohan

“…The common molecular mechanisms underlying psychiatric disorders are not well understood. Prior attempts to assess the pathological mechanisms responsible for…”
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Identification of candidate repurposable drugs to combat COVID-19 using a signature-based approach by O’Donovan, Sinead M., Imami, Ali, Eby, Hunter, Henkel, Nicholas D., Creeden, Justin Fortune, Asah, Sophie, Zhang, Xiaolu, Wu, Xiaojun, Alnafisah, Rawan, Taylor, R. Travis, Reigle, James, Thorman, Alexander, Shamsaei, Behrouz, Meller, Jarek, McCullumsmith, Robert E.

“…The COVID-19 pandemic caused by the novel SARS-CoV-2 is more contagious than other coronaviruses and has higher rates of mortality than influenza…”
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Cellular, molecular, and therapeutic characterization of pilocarpine-induced temporal lobe epilepsy by Henkel, Nicholas D., Smail, Marissa A., Wu, Xiaojun, Enright, Heather A., Fischer, Nicholas O., Eby, Hunter M., McCullumsmith, Robert E., Shukla, Rammohan

“…Animal models have expanded our understanding of temporal lobe epilepsy (TLE). However, translating these to cell-specific druggable hypotheses is not…”
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Terebratulide brachiopod shell biomineralization by mantle epithelial cells by Simonet Roda, M., Ziegler, A., Griesshaber, E., Yin, X., Rupp, U., Greiner, M., Henkel, D., Häussermann, V., Eisenhauer, A., Laudien, J., Schmahl, W.W.

“…[Display omitted] •Cell-reorganization; commissure: muti-cell-layered, central shell: single-cell-layered.•Individual fibres are secreted by several cells at…”
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Emerging Kinase Therapeutic Targets in Pancreatic Ductal Adenocarcinoma and Pancreatic Cancer Desmoplasia by Creeden, Justin F, Alganem, Khaled, Imami, Ali S, Henkel, Nicholas D, Brunicardi, F Charles, Liu, Shi-He, Shukla, Rammohan, Tomar, Tushar, Naji, Faris, McCullumsmith, Robert E

“…Kinase drug discovery represents an active area of therapeutic research, with previous pharmaceutical success improving patient outcomes across a wide variety…”
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Association of work load and mental disorders: review of the data by Rau, R, Henkel, D

“…Currently, the two faces of work as described by Kurt Lewin (The socialization of the Taylor system. A fundamental examination of work and vocational…”
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Disparities of Mortality Trends Due to Cerebrovascular Diseases and Cerebrovascular Infarction in the United States by Doddi, Sishir, Henkel, Nicholas D., Salichs, Oscar, Burgess, Richard, Hibshman, Taryn, Wright, Jonathan, Malik, Isa, Kasab, Sami Al, Jumaa, Mouhammad A.

“…BackgroundCerebrovascular diseases are a major cause of morbidity and mortality worldwide and are the fifth leading cause of death in the United States…”
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Recurrent mucosal erosions and violaceous patches by Willenbrink, Tyler J., Henkel, Emily D., Keeling, Brett H.

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Metabolic regulation of type I interferon production by O'Carroll, Shane M., Henkel, Fiona D. R., O'Neill, Luke A. J.

“…Summary Over the past decade, there has been a surge in discoveries of how metabolic pathways regulate immune cell function in health and disease, establishing…”
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Genetic and environmental contributions to cardiovascular risk factors in Mexican Americans : The San Antonio Family Heart Study by MITCHELL, B. D, KAMMERER, C. M, VANDEBERG, J. L, STERN, M. P, MACCLUER, J. W, BLANGERO, J, MAHANEY, M. C, RAINWATER, D. L, DYKE, B, HIXSON, J. E, HENKEL, R. D, SHARP, M, COMUZZIE, A. G

“…The familial aggregation of coronary heart disease can be in large part accounted for by a clustering of cardiovascular disease risk factors. To elucidate the…”
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NLRP12 drives PANoptosis in response to heme by Henkel, Fiona D.R., O’Neill, Luke A.J.

“…PANoptosomes are large cell death-inducing complexes that drive a type of cell death called PANoptosis during infection and inflammation. Sundaram and…”
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Schizophrenia: a disorder of broken brain bioenergetics by Henkel, Nicholas D., Wu, Xiajoun, O’Donovan, Sinead M., Devine, Emily A., Jiron, Jessica M., Rowland, Laura M., Sarnyai, Zoltan, Ramsey, Amy J., Wen, Zhexing, Hahn, Margaret K., McCullumsmith, Robert E.

“…A substantial and diverse body of literature suggests that the pathophysiology of schizophrenia is related to deficits of bioenergetic function. While…”
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Macrophages acquire a TNF-dependent inflammatory memory in allergic asthma by Lechner, Antonie, Henkel, Fiona D.R., Hartung, Franziska, Bohnacker, Sina, Alessandrini, Francesca, Gubernatorova, Ekaterina O., Drutskaya, Marina S., Angioni, Carlo, Schreiber, Yannick, Haimerl, Pascal, Ge, Yan, Thomas, Dominique, Kabat, Agnieszka M., Pearce, Edward J., Ohnmacht, Caspar, Nedospasov, Sergei A., Murray, Peter J., Chaker, Adam M., Schmidt-Weber, Carsten B., Esser-von Bieren, Julia

“…Infectious agents can reprogram or “train” macrophages and their progenitors to respond more readily to subsequent insults. However, whether such an…”
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Inflammatory macrophage memory in nonsteroidal anti-inflammatory drug–exacerbated respiratory disease by Haimerl, Pascal, Bernhardt, Ulrike, Schindela, Sonja, Henkel, Fiona D.R., Lechner, Antonie, Zissler, Ulrich M., Pastor, Xavier, Thomas, Dominique, Cecil, Alexander, Ge, Yan, Haid, Mark, Prehn, Cornelia, Tokarz, Janina, Heinig, Matthias, Adamski, Jerzy, Schmidt-Weber, Carsten B., Chaker, Adam M., Esser-von Bieren, Julia

“…Nonsteroidal anti-inflammatory drug–exacerbated respiratory disease (N-ERD) is a chronic inflammatory condition, which is driven by an aberrant arachidonic…”
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Pediatric trichotillomania: Review of management by Henkel, Emily D., Jaquez, Sasha D., Diaz, Lucia Z.

“…Trichotillomania can present in childhood, with many families seeking initial evaluation by a dermatologist for hair loss. Prompt and accurate diagnosis by…”
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Effects of Early Enteral to Parenteral Protein Ratios on Brain Volume and Somatic Growth in Very Low Birth Weight Infants by Henkel, Rebecca D., Fu, Ting Ting, Barnes-Davis, Maria E., Sahay, Rashmi D., Liu, Chunyan, Hill, Crystal D., Ehrlich, Shelley R., Parikh, Nehal A.

“…To evaluate whether a higher proportion of enteral vs parenteral protein ratio (E:P ratio) in the first 28 days after birth is associated with increased brain…”
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Signature-based approaches for informed drug repurposing: targeting CNS disorders by Shukla, Rammohan, Henkel, Nicholas D, Alganem, Khaled, Hamoud, Abdul-Rizaq, Reigle, James, Alnafisah, Rawan S, Eby, Hunter M, Imami, Ali S, Creeden, Justin F, Miruzzi, Scott A, Meller, Jaroslaw, Mccullumsmith, Robert E

“…CNS disorders, and in particular psychiatric illnesses, lack definitive disease-altering therapeutics. The limited understanding of the mechanisms driving…”
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Pigmentation Disorders in the Elderly by Armenta, Andrew M., Henkel, Emily D., Ahmed, Ammar M.

“…Aging skin is subject to morphological change due to both intrinsic (skin tone, genetics, endogenous hormones) and extrinsic (chronic sun exposure,…”
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Early and consistent safe sleep practices in the neonatal intensive care unit: a sustained regional quality improvement initiative by Napolitano, Stephanie K., Boswell, Nicole L., Froese, Patricia, Henkel, Rebecca D., Barnes-Davis, Maria E., Parham, Danielle K.

“…Objective To increase compliance with standardized safe sleep recommendations for patients in a cohort of regional level III/IV neonatal intensive care units…”
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Optimizing pediatric periprocedural pain management part I-Evolving ethics and topical anesthetics by Henkel, Emily D, Haller, Courtney N, Diaz, Lucia Z, Ricles, Victoria, Wong Grossman, Ashley V, Nemergut, Michael E, Krakowski, Andrew C

“…Pediatric procedure-related pain management is often incompletely understood, inadequately addressed, and critical in influencing a child's lifelong…”
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