Search Results - "Henke, Tina"

Botulinum neurotoxin C mutants reveal different effects of syntaxin or SNAP-25 proteolysis on neuromuscular transmission by Zanetti, Giulia, Sikorra, Stefan, Rummel, Andreas, Krez, Nadja, Duregotti, Elisa, Negro, Samuele, Henke, Tina, Rossetto, Ornella, Binz, Thomas, Pirazzini, Marco

“…Botulinum neurotoxin serotype C (BoNT/C) is a neuroparalytic toxin associated with outbreaks of animal botulism, particularly in birds, and is the only BoNT…”
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Substrate Recognition Mechanism of VAMP/Synaptobrevin-cleaving Clostridial Neurotoxins by Sikorra, Stefan, Henke, Tina, Galli, Thierry, Binz, Thomas

“…Botulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT) inhibit neurotransmitter release by proteolyzing a single peptide bond in one of the three soluble…”
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Synaptotagmins I and II Act as Nerve Cell Receptors for Botulinum Neurotoxin G by Rummel, Andreas, Karnath, Tino, Henke, Tina, Bigalke, Hans, Binz, Thomas

“…Botulinum neurotoxins (BoNTs) induce muscle paralysis by selectively entering cholinergic motoneurons and subsequent specific cleavage of core components of…”
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Duplication of clostridial binding domains for enhanced macromolecular delivery into neurons by Leese, Charlotte, Bresnahan, Rebecca, Doran, Ciara, Simsek, Deniz, Fellows, Alexander D., Restani, Laura, Caleo, Matteo, Schiavo, Giampietro, Mavlyutov, Timur, Henke, Tina, Binz, Thomas, Davletov, Bazbek

“…Neurological diseases constitute a quarter of global disease burden and are expected to rise worldwide with the ageing of human populations. There is an…”
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Probing the Properties of PTEN-Specific Botulinum Toxin Type E Mutants by Pirazzini, Marco, Schiavone, Giorgia, Henke, Tina, Binz, Thomas

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Neutralisation of specific surface carboxylates speeds up translocation of botulinum neurotoxin type B enzymatic domain by Pirazzini, Marco, Henke, Tina, Rossetto, Ornella, Mahrhold, Stefan, Krez, Nadja, Rummel, Andreas, Montecucco, Cesare, Binz, Thomas

“…•Three specific surface carboxylates of BoNT/B were neutralised by mutation to amide.•The triple mutant expedites entry of the enzymatic domain into…”
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In vitro and in vivo evaluation of syntaxin-specific BoNT/C by Zanetti, Giulia, Pirazzini, Marco, Rossetto, Ornella, Megighian, Aram, Henke, Tina, Rummel, Andreas, Binz, Thomas, Montecucco, Cesare

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172. Effects of a syntaxin-specific botulinum neurotoxin type C on mice by Rossetto, Ornella, Zanetti, Giulia, Pirazzini, Marco, Tehran, Domenico Azarnia, Megighian, Aram, Henke, Tina, Binz, Thomas, Montecucco, Cesare

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Substrate Recognition Mechanism of VAMP/Synaptobrevin-cleaving Clostridial NeurotoxinsS by Sikorra, Stefan, Henke, Tina, Galli, Thierry, Binz, Thomas

“…Botulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT) inhibit neurotransmitter release by proteolyzing a single peptide bond in one of the three soluble…”
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Identification of the Amino Acid Residues Rendering TI-VAMP Insensitive toward Botulinum Neurotoxin B by Sikorra, Stefan, Henke, Tina, Swaminathan, Subramanyam, Galli, Thierry, Binz, Thomas

“…Botulinum neurotoxins types B, D, F, and G, and tetanus neurotoxin inhibit vesicular fusion via proteolytic cleavage of VAMP/Synaptobrevin, a core component of…”
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Substrate recognition mechanism of VAMP/synaptobrevin cleaving clostridial neurotoxins by Stefan, Sikorra, Tina, Henke, Thierry, Galli, Thomas, Binz

“…Information on the mechanism of VAMP/synaptobrevin proteolysis by BoNT/D, F, and TeNT is still fragmentary. Here, we report the analysis of the contribution of…”
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