Search Results - "Henke, Markus"

Macrolide antibiotics as immunomodulatory medications: proposed mechanisms of action by Shinkai, Masaharu, Henke, Markus O, Rubin, Bruce K

“…Macrolide antibiotics administered in sub-antimicrobial doses improve pulmonary function and decrease exacerbation frequency for persons with diffuse…”
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Secretory Hyperresponsiveness and Pulmonary Mucus Hypersecretion by Rubin, Bruce K., MD, MEngr, MBA, Priftis, Kostas N., MD, PhD, Schmidt, H. Joel, MD, FCCP, Henke, Markus O., MD

“…The term bronchial hyperresponsiveness is generally used to describe a heightened airway smooth muscle bronchoconstrictor response measured by…”
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A Worm-Like Biomimetic Crawling Robot Based on Cylindrical Dielectric Elastomer Actuators by Pfeil, Sascha, Henke, Markus, Katzer, Konrad, Zimmermann, Martina, Gerlach, Gerald

“…In recent years the field of soft robotics has gained a lot of interest both in academia and industry. In contrast to rigid robots, which are potentially very…”
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Challenges and Opportunities of Very Light High-Performance Electric Drives for Aviation by Henke, Markus, Narjes, Gerrit, Hoffmann, Jan, Wohlers, Constantin, Urbanek, Stefan, Heister, Christian, Steinbrink, Jörn, Canders, Wolf-Rüdiger, Ponick, Bernd

“…The demand for alternative fueling methods to reduce the need for fossil fuels is not limited to the electrification of ground vehicles. More-electric and…”
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Impact of Current Density and Cooling on the Weight Balance of Electrical Propulsion Drives for Aviation by Hoffmann, Jan, Canders, Wolf-Rüdiger, Henke, Markus

“…Through applying an exemplary design study, the dependencies between current density, temperatures, and weight in an electrical drive system for a small range…”
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Cryogenically-cooled Power Electronics for long-distance Aircraft by Schefer, Hendrik, Canders, Wolf-Rudiger, Hoffmann, Jan, Mallwitz, Regine, Henke, Markus

“…New aerodynamic aircraft concepts enable the storage of volumetric liquid hydrogen (LH2). Additionally, the low temperatures of LH2 allow technologies such as…”
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Serine Proteases Degrade Airway Mucins in Cystic Fibrosis by HENKE, Markus O, JOHN, Gerrit, RHEINECK, Christina, CHILLAPPAGARI, Shashi, NAEHRLICH, Lutz, RUBIN, Bruce K

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Impaired TLR4 and HIF expression in cystic fibrosis bronchial epithelial cells downregulates hemeoxygenase-1 and alters iron homeostasis in vitro by Chillappagari, Shashi, Venkatesan, Shalini, Garapati, Virajith, Mahavadi, Poornima, Munder, Antje, Seubert, Andreas, Sarode, Gaurav, Guenther, Andreas, Schmeck, Bernd T, Tümmler, Burkhard, Henke, Markus O

“…Hemeoxygenase-1 (HO-1), an inducible heat shock protein, is upregulated in response to multiple cellular insults via oxidative stress, lipopolysaccharides…”
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MUC5AC and MUC5B Mucins Increase in Cystic Fibrosis Airway Secretions during Pulmonary Exacerbation by Henke, Markus O, John, Gerrit, Germann, Michele, Lindemann, Hermann, Rubin, Bruce K

“…Cystic fibrosis (CF) is believed to be associated with mucus hypersecretion; thus, the principal airway gel-forming mucins, MUC5AC and MUC5B, are also expected…”
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Concept of a sensor-integrating jaw coupling for measuring operating data by Ewert, Arthur, Menning, Johannes D. M., Prokopchuk, Artem, Rosenlöcher, Thomas, Henke, E.-F. Markus, Wallmersperger, Thomas, Schlecht, Berthold

“…In recent years, industry and research (i) have driven the development and application of data-driven machines and systems and (ii) have increasingly…”
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Mucolytics in cystic fibrosis by Henke, Markus O, Ratjen, Felix

“…Summary Mucus accumulation in the lower airways is a key feature of cystic fibrosis (CF) lung disease. The major component of mucus in CF is not mucin derived…”
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TLR-4-mediated innate immunity is reduced in cystic fibrosis airway cells by John, Gerrit, Yildirim, Ali O, Rubin, Bruce K, Gruenert, Dieter C, Henke, Markus O

“…Airway epithelial cells contribute to the inflammatory response of the lung, and their innate immune response is primarily mediated via Toll-like receptor…”
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One Soft Step: Bio-Inspired Artificial Muscle Mechanisms for Space Applications by Ashby, Joseph, Rosset, Samuel, Henke, E-F Markus, Anderson, Iain A

“…Soft robots, devices with deformable bodies and powered by soft actuators, may fill a hitherto unexplored niche in outer space. All space-bound payloads are…”
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Magnetic loss measurement of surface-mounted permanent magnet synchronous machines used in explosive environments by Yogal, Nijan, Lehrmann, Christian, Henke, Markus

“…High energy-efficient permanent magnet synchronous machines (PMSMs) with low manufacturing costs and easy controllability are in high demand for the automotive…”
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Altered protease and antiprotease balance during a COPD exacerbation contributes to mucus obstruction by Chillappagari, Shashi, Preuss, Jenni, Licht, Sebastian, Müller, Christian, Mahavadi, Poornima, Sarode, Gaurav, Vogelmeier, Claus, Guenther, Andreas, Nahrlich, Lutz, Rubin, Bruce K, Henke, Markus O

“…Proteases have been shown to degrade airway mucin proteins and to damage the epithelium impairing mucociliary clearance. There are increased proteases in the…”
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Characteristics of Current Smokers versus Former Smokers with COPD and Their Associations with Smoking Cessation Within 4.5 Years: Results from COSYCONET by Alter, Peter, Stoleriu, Cosmina, Kahnert, Kathrin, Henke, Markus Oliver, Bals, Robert, Trudzinski, Franziska C, Watz, Henrik, Speicher, Tim, Söhler, Sandra, Welte, Tobias, Rabe, Klaus F, Wouters, Emiel F M, Vogelmeier, Claus F, Jörres, Rudolf A

“…Many patients with chronic obstructive pulmonary disease (COPD) continue smoking. We used data from the "real-life" COSYCONET COPD cohort to evaluate whether…”
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The Role of DNA and Actin Polymers on the Polymer Structure and Rheology of Cystic Fibrosis Sputum and Depolymerization by Gelsolin or Thymosin Beta 4 by KATER, ARNON, HENKE, MARKUS O., RUBIN, BRUCE K.

“…:  Mucus clearance is the first line of pulmonary defense against inhaled irritants, microorganisms, and allergens. In health, the gel‐forming mucins are the…”
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Immunomodulatory activity and effectiveness of macrolides in chronic airway disease by Rubin, Bruce K, Henke, Markus O

“…The use of troleandomycin as adjunctive therapy for the treatment of patients with corticosteroid-dependent asthma first suggested an immunomodulatory effect…”
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A Review on Sensor‐Integrating Machine Elements by Kirchner, Eckhard, Wallmersperger, Thomas, Gwosch, Thomas, Menning, Johannes D. M., Peters, Julian, Breimann, Richard, Kraus, Benjamin, Welzbacher, Peter, Küchenhof, Jan, Krause, Dieter, Knoll, Erich, Otto, Michael, Muhammedi, Benjamin, Seltmann, Stephanie, Hasse, Alexander, Schäfer, Günter, Lohrengel, Armin, Thielen, Stefan, Stiemcke, Yvo, Koch, Oliver, Ewert, Arthur, Rosenlöcher, Thomas, Schlecht, Berthold, Prokopchuk, Artem, Henke, Ernst‐Friedrich Markus, Herbst, Felix, Matthiesen, Sven, Riehl, David, Keil, Ferdinand, Hofmann, Klaus, Pape, Florian, Konopka, Dennis, Poll, Gerhard, Steppeler, Tobias, Ottermann, Rico, Dencker, Folke, Wurz, Marc C., Puchtler, Steffen, Baszenski, Thao, Winnertz, Martin, Jacobs, Georg, Lehmann, Benjamin, Stahl, Karsten

“…This contribution summarizes the current state of research regarding so‐called sensor‐integrating machine elements as an enabler of digitalization in…”
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A small molecule neutrophil elastase inhibitor, KRP-109, inhibits cystic fibrosis mucin degradation by Chillappagari, Shashi, Müller, Christian, Mahavadi, Poornima, Guenther, Andreas, Nährlich, Lutz, Rosenblum, Jonathan, Rubin, Bruce K, Henke, Markus O

“…Abstract Background Neutrophil elastase (NE) rapidly degrades gel-forming airway mucins in cystic fibrosis (CF) sputum. We hypothesized that KRP-109, a small…”
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