Search Results - "Henke, Elisa"
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Conceptual design of a generic data harmonization process for OMOP common data model
Published in BMC medical informatics and decision making (26-02-2024)“…To gain insight into the real-life care of patients in the healthcare system, data from hospital information systems and insurance systems are required…”
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How to customize common data models for rare diseases: an OMOP-based implementation and lessons learned
Published in Orphanet journal of rare diseases (14-08-2024)“…Given the geographical sparsity of Rare Diseases (RDs), assembling a cohort is often a challenging task. Common data models (CDM) can harmonize disparate…”
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Opportunities of Digital Infrastructures for Disease Management-Exemplified on COVID-19-Related Change in Diagnosis Counts for Diabetes-Related Eye Diseases
Published in Nutrients (11-05-2022)“…Retrospective research on real-world data provides the ability to gain evidence on specific topics especially when running across different sites in research…”
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An Extract-Transform-Load Process Design for the Incremental Loading of German Real-World Data Based on FHIR and OMOP CDM: Algorithm Development and Validation
Published in JMIR medical informatics (21-08-2023)“…Abstract Background In the Medical Informatics in Research and Care in University Medicine (MIRACUM) consortium, an IT-based clinical trial recruitment support…”
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Assessing the Use of German Claims Data Vocabularies for Research in the Observational Medical Outcomes Partnership Common Data Model: Development and Evaluation Study
Published in JMIR medical informatics (07-11-2023)“…Abstract Background National classifications and terminologies already routinely used for documentation within patient care settings enable the unambiguous…”
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Use of Metadata-Driven Approaches for Data Harmonization in the Medical Domain: Scoping Review
Published in JMIR medical informatics (14-02-2024)“…Multisite clinical studies are increasingly using real-world data to gain real-world evidence. However, due to the heterogeneity of source data, it is…”
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Streamlining intersectoral provision of real-world health data: a service platform for improved clinical research and patient care
Published in Frontiers in medicine (05-06-2024)“…Obtaining real-world data from routine clinical care is of growing interest for scientific research and personalized medicine. Despite the abundance of medical…”
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Secondary use of patient data within decentralized studies using the example of rare diseases in Germany: A data scientist's exploration of process and lessons learned
Published in Digital health (01-01-2024)“…Unlocking the potential of routine medical data for clinical research requires the analysis of data from multiple healthcare institutions. However, according…”
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An ETL-process design for data harmonization to participate in international research with German real-world data based on FHIR and OMOP CDM
Published in International journal of medical informatics (Shannon, Ireland) (01-01-2023)“…•German CDS is defined in HL7 FHIR for better interoperability across university hospitals.•ETL process was developed using SpringBatch to transform German CDS…”
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Predictors of improvement in disease activity in childhood and adolescent Crohn’s disease: an analysis of age, localization, initial severity and drug therapy — data from the Saxon Registry for Inflammatory Bowel Disease in Children in Germany (2000–2014)
Published in European journal of pediatrics (01-10-2024)“…The escalating worldwide prevalence of Crohn’s disease (CD) among children and adolescents, coupled with a trend toward earlier onset, presents significant…”
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A systematic review and meta-regression on international trends in the incidence of ulcerative colitis in children and adolescents associated with socioeconomic and geographic factors
Published in European journal of pediatrics (01-04-2024)“…The incidence of ulcerative colitis (UC) among children and adolescents is rising globally, albeit with notable discrepancies across countries. This systematic…”
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Towards ETL Processes to OMOP CDM Using Metadata and Modularization
Published in Studies in health technology and informatics (18-05-2023)“…OMOP common data model (CDM) is designed for analyzing large clinical data and building cohorts for medical research, which requires Extract-Transform-Load…”
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German Claims Data for Real-World Research: Content Coverage Evaluation in OMOP CDM
Published in Studies in health technology and informatics (18-05-2023)“…Research on real-world data is becoming increasingly important. The current restriction to clinical data in Germany limits the view of the patient. To gain…”
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Enhancing Patient Care: Evaluating Clinical Utility in Measurement Instruments
Published in Studies in health technology and informatics (22-08-2024)“…The evaluation of clinical utility is essential for the successful adoption of new technology in clinical practice. An approach to evaluating clinical utility…”
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Towards Efficient Resource Utilization Forecasting in Acute Heat Events Using OMOP
Published in Studies in health technology and informatics (22-08-2024)“…Predicting resource utilization can help to optimize the distribution of limited resources in the healthcare system. This requires different climatic and…”
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Fitness for Use of Anatomical Therapeutic Classification for Real World Data Research
Published in Studies in health technology and informatics (18-05-2023)“…Real-world data (RWD) is gaining importance in research. For instance, the European Medicines Agency (EMA) is currently in the process of establishing a…”
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Towards the Improvement of Clinical Guidelines Based on Real World Data
Published in Studies in health technology and informatics (25-05-2022)“…Computerized clinical guidelines (CCG) are effective instruments for standardizing, monitoring and optimizing medical treatment processes. Nevertheless, due to…”
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