Search Results - "Henk te Velthuis"
-
1
N Latex FLC - new monoclonal high-performance assays for the determination of free light chain kappa and lambda
Published in Clinical chemistry and laboratory medicine (01-08-2011)“…High serum concentrations of monoclonal free light chain (FLC) kappa or lambda are markers of plasma cell dyscrasia. We developed new, latex-enhanced, specific…”
Get more information
Journal Article -
2
State and diagnostic value of plasma tissue factor in early‐hospitalised patients with chest pain
Published in British journal of haematology (01-10-2005)“…Summary To study the state and diagnostic value of plasma tissue factor (TF) in patients with acute coronary syndromes (ACS), we quantitatively compared plasma…”
Get full text
Journal Article -
3
Impact of simvastatin on hemostatic and fibrinolytic regulators in Type 2 diabetes mellitus
Published in Diabetes research and clinical practice (01-11-2005)“…Simvastatin, a widely used 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitor, effectively reduced cardiac death and ischemic events in patients with…”
Get full text
Journal Article -
4
Simultaneous detection of 15 human cytokines in a single sample of stimulated peripheral blood mononuclear cells
Published in Clinical and diagnostic laboratory immunology (01-01-2003)“…Cytokines secreted by cells of the immune system can alter the behavior and properties of immune or other cells. At a site of inflammation, sets of cytokines…”
Get full text
Journal Article -
5
Identification of a putative binding site for negatively charged surfaces in the fibronectin type II domain of human factor XII--an immunochemical and homology modeling approach
Published in Thrombosis and haemostasis (01-12-2000)“…Monoclonal antibodies directed against functional sites of proteins provide useful tools for structure-function studies. Here we describe a mAb, KOK5, directed…”
Get more information
Journal Article -
6
Label-free assessment of high-affinity antibody–antigen binding constants. Comparison of bioassay, SPR, and PEIA-ellipsometry
Published in Journal of immunological methods (28-02-2011)“…Assessment of high-affinity antibody–antigen binding parameters is important in such diverse areas as selection of therapeutic antibodies, detection of…”
Get full text
Journal Article -
7
Clinical comparison of new monoclonal antibody-based nephelometric assays for free light chain kappa and lambda to polyclonal antibody-based assays and immunofixation electrophoresis
Published in Clinical chemistry and laboratory medicine (01-03-2012)“…New monoclonal antibody-based assays for serum-free light chains (FLC) have become available. In a clinical study with 541 patients, the new N Latex FLC assays…”
Get more information
Journal Article -
8
Intrapatient Variability in the Pharmacokinetics of Etanercept Maintenance Treatment
Published in Therapeutic drug monitoring (01-08-2017)“…Etanercept has shown to mediate a favorable effect on immune-mediated inflammatory diseases (IMID), including plaque psoriasis. Therapeutic drug monitoring…”
Get full text
Journal Article -
9
Nucleosome-releasing factor: a new role for factor VII-activating protease (FSAP)
Published in The FASEB journal (01-12-2008)“…Plasma proteins such as early complement components and IgM are involved in the removal of late apoptotic or secondary necrotic (sn) cells. We have recently…”
Get full text
Journal Article -
10
Heparin-protamine complexes and C-reactive protein induce activation of the classical complement pathway: studies in patients undergoing cardiac surgery and in vitro
Published in Thrombosis and haemostasis (01-08-2000)“…The administration of protamine to patients undergoing cardiopulmonary bypass (CPB) to neutralize heparin and to reduce the risk of bleeding, induces…”
Get more information
Journal Article -
11
Activation of the Complement system during and after cardiopulmonary bypass surgery : Postsurgery activation involves C-reactive protein and is associated with postoperative arrhythmia
Published in Circulation (New York, N.Y.) (18-11-1997)“…Complement activation during cardiopulmonary bypass (CPB) surgery is considered to result from interaction of blood with the extracorporeal circuit. We…”
Get full text
Journal Article -
12
A plasma nucleosome releasing factor (NRF) with serine protease activity is instrumental in removal of nucleosomes from secondary necrotic cells
Published in FEBS letters (27-11-2007)“…We observed that interaction of secondary necrotic (sn) cells with human serum or plasma leads to loss of DNA staining. The decrease turned out to be a result…”
Get full text
Journal Article -
13
Specific complement inhibition with heparin-coated extracorporeal circuits
Published in The Annals of thoracic surgery (01-04-1996)“…Although it is well established that heparin-coated extracorporeal circuits reduce complement activation during cardiac operations, little in vivo information…”
Get full text
Journal Article -
14
Effect of preoperative oral immune-enhancing nutritional supplement on patients at high risk of infection after cardiac surgery: a randomised placebo-controlled trial
Published in The Lancet (British edition) (01-09-2001)“…Elderly patients and those with poor ventricular function have increased morbidity and mortality rates when undergoing surgery. We aimed to ascertain whether…”
Get full text
Journal Article -
15
Glycine Does Not Add to the Beneficial Effects of Perioperative Oral Immune-Enhancing Nutrition Supplements in High-Risk Cardiac Surgery Patients
Published in JPEN. Journal of parenteral and enteral nutrition (01-05-2007)“…Background: Elderly patients and patients with a poor cardiac function have increased morbidity rates when undergoing cardiac surgery. The aim of this study…”
Get full text
Journal Article -
16
Reduced complement activation and improved postoperative performance after cardiopulmonary bypass with heparin-coated circuits
Published in The Journal of thoracic and cardiovascular surgery (01-09-1995)“…A randomized controlled trial that involved 30 patients undergoing elective coronary artery bypass grafting was done to determine the effect of heparin-coated…”
Get full text
Journal Article -
17
Heparin coating of extracorporeal circuits inhibits contact activation during cardiac operations
Published in The Journal of thoracic and cardiovascular surgery (01-07-1997)“…Objective: Heparin coating reduces complement activation on the surface of extracorporeal circuits. In this study we investigated its effect on activation of…”
Get full text
Journal Article -
18
Measurement of free light chains with assays based on monoclonal antibodies
Published in Clinical chemistry and laboratory medicine (01-06-2016)“…Recently, serum free light chain (FLC) assays incorporating anti-kappa (κ) and anti-lambda (λ) FLC monoclonal antibodies have become available: N Latex FLC…”
Get more information
Journal Article -
19
Myocardial performance in elderly patients after cardiopulmonary bypass is suppressed by tumor necrosis factor
Published in The Journal of thoracic and cardiovascular surgery (01-12-1995)“…The aim of this study was to determine whether elderly patients (aged > 65 years, n = 20) in comparison with younger patients (aged < 55 years, n = 23)…”
Get full text
Journal Article -
20
N Latex FLC serum free light-chain assays in patients with renal impairment
Published in Clinical chemistry and laboratory medicine (01-06-2014)“…The aim of this study was to establish ranges for N Latex free light-chain (FLC) monoclonal-based nephelometric assays in patients with renal impairment. In…”
Get more information
Journal Article