Search Results - "Henk P. Roest"

Evaluation of RNA isolation methods for microRNA quantification in a range of clinical biofluids by Roest, Henk P, IJzermans, Jan N M, van der Laan, Luc J W

“…Extracellular microRNAs (miRNAs), released from cells into biofluids, have emerged as promising biomarkers for diagnostic and prognostic purposes. Several RNA…”
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Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks by Motegi, Akira, Liaw, Hung-Jiun, Lee, Kyoo-Young, Roest, Henk P, Maas, Alex, Wu, Xiaoli, Moinova, Helen, Markowitz, Sanford D, Ding, Hao, Hoeijmakers, Jan H.J, Myung, Kyungjae

“…Chronic stalling of DNA replication forks caused by DNA damage can lead to genomic instability. Cells have evolved lesion bypass pathways such as…”
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Liver Ischemia and Reperfusion Induce Periportal Expression of Necroptosis Executor pMLKL Which Is Associated With Early Allograft Dysfunction After Transplantation by Shi, Shaojun, Bonaccorsi-Riani, Eliano, Schurink, Ivo, van den Bosch, Thierry, Doukas, Michael, Lila, Karishma A, Roest, Henk P, Xhema, Daela, Gianello, Pierre, de Jonge, Jeroen, Verstegen, Monique M A, van der Laan, Luc J W

“…Early allograft dysfunction (EAD) following liver transplantation (LT) remains a major threat to the survival of liver grafts and recipients. In animal models,…”
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Modelling metastatic colonization of cholangiocarcinoma organoids in decellularized lung and lymph nodes by van Tienderen, Gilles S, van Beek, Marije E A, Schurink, Ivo J, Rosmark, Oskar, Roest, Henk P, Tieleman, Jantine, Demmers, Jeroen, Muntz, Iain, Conboy, James, Westergren-Thorsson, Gunilla, Koenderink, Gijsje, van der Laan, Luc Jw, Verstegen, Monique M A

“…Cholangiocarcinoma (CCA) is a type of liver cancer with an aggressive phenotype and dismal outcome in patients. The metastasis of CCA cancer cells to distant…”
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Human lymph node fibroblastic reticular cells maintain heterogeneous characteristics in culture by Roet, Janna E.G., Morrison, Andrew I., Mikula, Aleksandra M., de Kok, Michael, Panocha, Daphne, Roest, Henk P., van der Laan, Luc J.W., de Winde, Charlotte M., Mebius, Reina E.

“…Fibroblastic reticular cells (FRCs) are mesenchymal stromal cells in human lymph nodes (LNs) playing a pivotal role in adaptive immunity. Several FRC subsets…”
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Human Bile Contains Cholangiocyte Organoid-Initiating Cells Which Expand as Functional Cholangiocytes in Non-canonical Wnt Stimulating Conditions by Roos, Floris J M, Verstegen, Monique M A, Muñoz Albarinos, Laura, Roest, Henk P, Poley, Jan-Werner, Tetteroo, Geert W M, IJzermans, Jan N M, van der Laan, Luc J W

“…Diseases of the bile duct (cholangiopathies) remain a common indication for liver transplantation, while little progress has been made over the last decade in…”
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Collagen peptides in urine: a new promising biomarker for the detection of colorectal liver metastases by Bröker, Mirelle E E, Lalmahomed, Zarina S, Roest, Henk P, van Huizen, Nick A, Dekker, Lennard J M, Calame, Wim, Verhoef, Cornelis, Ijzermans, Jan N M, Luider, Theo M

“…For both patients and the outpatient clinic the frequent follow-up visits after a resection of colorectal cancer (CRC) are time consuming and due to large…”
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Preoperative fasting protects mice against hepatic ischemia/reperfusion injury: mechanisms and effects on liver regeneration by Verweij, Mariëlle, van Ginhoven, Tessa M., Mitchell, James R., Sluiter, Wim, den Engel, Sandra van, Roest, Henk P., Torabi, Elham, IJzermans, Jan N. M., Hoeijmakers, Jan H. J., de Bruin, Ron W. F.

“…We show that brief periods of fasting induce functional changes similar to those induced by long‐term dietary restriction in mice, and these changes include…”
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Inflammatory genes in rat livers from cardiac- and brain death donors by Saat, Tanja C., MSc, Susa, Denis, MD, PhD, Kok, Niels F.M., MD, PhD, van den Engel, Sandra, BSc, Roest, Henk P., PhD, van der Laan, Luc J.W., PhD, IJzermans, Jan N.M., MD, PhD, de Bruin, Ron W.F., PhD

“…Abstract Background Liver transplantation (LT) is the only life-saving treatment for patients with end-stage liver disease. The increase in patients has…”
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The Ubiquitin-Conjugating DNA Repair Enzyme HR6A Is a Maternal Factor Essential for Early Embryonic Development in Mice by Roest, Henk P., Baarends, Willy M., de Wit, Jan, van Klaveren, Jan W., Wassenaar, Evelyne, Hoogerbrugge, Jos W., van Cappellen, Wiggert A., Hoeijmakers, Jan H. J., Grootegoed, J. Anton

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Histone Ubiquitination and Chromatin Remodeling in Mouse Spermatogenesis by Baarends, Willy M, Hoogerbrugge, Jos W, Roest, Henk P, Ooms, Marja, Vreeburg, Jan, Hoeijmakers, Jan H.J, Grootegoed, J.Anton

“…Male infertility inHR6Bknockout mice is associated with impairment of spermatogenesis. TheHR6Bgene is a mammalian, autosomal homolog of theSaccharomyces…”
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Letter to the Editor: The mucosal gut signature in primary sclerosing cholangitis before and after liver transplantation. Is the dysbiosis index really predictive for the recurrence of PSC? by Mammadov, Ruslan A, Visseren, Thijmen, Roest, Henk P, van der Laan, Luc J W, Peppelenbosch, Maikel P

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Loss of HR6B Ubiquitin-Conjugating Activity Results in Damaged Synaptonemal Complex Structure and Increased Crossing-Over Frequency during the Male Meiotic Prophase by Baarends, Willy M., Wassenaar, Evelyne, Hoogerbrugge, Jos W., van Cappellen, Gert, Roest, Henk P., Vreeburg, Jan, Ooms, Marja, Hoeijmakers, Jan H. J., Grootegoed, J. Anton

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Human extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct disease by Verstegen, Monique M. A., Roos, Floris J. M., Burka, Ksenia, Gehart, Helmuth, Jager, Myrthe, de Wolf, Maaike, Bijvelds, Marcel J. C., de Jonge, Hugo R., Ardisasmita, Arif I., van Huizen, Nick A., Roest, Henk P., de Jonge, Jeroen, Koch, Michael, Pampaloni, Francesco, Fuchs, Sabine A., Schene, Imre F., Luider, Theo M., van der Doef, Hubert P. J., Bodewes, Frank A. J. A., de Kleine, Ruben H. J., Spee, Bart, Kremers, Gert-Jan, Clevers, Hans, IJzermans, Jan N. M., Cuppen, Edwin, van der Laan, Luc J. W.

“…The development, homeostasis, and repair of intrahepatic and extrahepatic bile ducts are thought to involve distinct mechanisms including proliferation and…”
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Intestinal Bacteremia After Liver Transplantation Is a Risk Factor for Recurrence of Primary Sclerosing Cholangitis by Mammadov, Ruslan A., Selten, Jasmijn W., Roest, Henk P., Verhoeven, Cornelia J., Maroni, Luca, Bril, Sandra I., Tolenaars, Dagmar, Gadjradj, Pravesh S., van de Graaf, Stan F.J., Oude Elferink, Ronald P.J., Kwekkeboom, Jaap, Metselaar, Herold J., Peppelenbosch, Maikel P., Beuers, Ulrich, IJzermans, Jan N.M., van der Laan, Luc J.W.

“…Primary sclerosing cholangitis (PSC) is a chronic progressive pathological process, related to inflammatory bowel disease and subsequent bacterial…”
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Unbiased method for spectral analysis of cells with great diversity of autofluorescence spectra by Roet, Janna E. G., Mikula, Aleksandra M., Kok, Michael, Chadick, Cora H., Garcia Vallejo, Juan J., Roest, Henk P., Laan, Luc J. W., Winde, Charlotte M., Mebius, Reina E.

“…Autofluorescence is an intrinsic feature of cells, caused by the natural emission of light by photo‐excitatory molecular content, which can complicate analysis…”
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The release of microRNA‐122 during liver preservation is associated with early allograft dysfunction and graft survival after transplantation by Selten, Jasmijn W., Verhoeven, Cornelia J., Heedfeld, Veerle, Roest, Henk P., de Jonge, Jeroen, Pirenne, Jacques, van Pelt, Jos, Ijzermans, Jan. N. M., Monbaliu, Diethard, van der Laan, Luc J. W.

“…Early allograft dysfunction (EAD) after liver transplantation (LT) is associated with inferior graft survival. EAD is more prevalent in grafts from donation…”
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Identification and Validation Model for Informative Liquid Biopsy-Based microRNA Biomarkers: Insights from Germ Cell Tumor In Vitro, In Vivo and Patient-Derived Data by Lobo, João, Gillis, Ad J M, van den Berg, Annette, Dorssers, Lambert C J, Belge, Gafanzer, Dieckmann, Klaus-Peter, Roest, Henk P, van der Laan, Luc J W, Gietema, Jourik, Hamilton, Robert J, Jerónimo, Carmen, Henrique, Rui, Salvatori, Daniela, Looijenga, Leendert H J

“…Liquid biopsy-based biomarkers, such as microRNAs, represent valuable tools for patient management, but often do not make it to integration in the clinic. We…”
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Cell-free MicroRNA miR-505-3p in Graft Preservation Fluid Is an Independent Predictor of Delayed Graft Function After Kidney Transplantation by Roest, Henk P, Ooms, Liselotte S.S, Gillis, Ad J.M, IJzermans, Jan N.M, Looijenga, Leendert H.J, Dorssers, Lambert C.J, Dor, Frank J.M.F, van der Laan, Luc J.W

“…BACKGROUNDDelayed graft function (DGF), a common complication after transplantation of deceased donor kidneys, affects both short- and long-term outcomes…”
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Cell‐free microRNAs as early predictors of graft viability during ex vivo normothermic machine perfusion of human donor livers by Matton, Alix P. M., Selten, Jasmijn W., Roest, Henk P., Jonge, Jeroen, IJzermans, Jan N. M., Meijer, Vincent E., Porte, Robert J., Laan, Luc J. W.

“…Background Cell‐free microRNAs (miRs) have emerged as early and sensitive biomarkers for tissue injury and function. This study aimed to investigate whether…”
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